Enhydra lutris kenyoni (northern sea otter): 111161798
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Entry
111161798 CDS
T05871
Name
(RefSeq) insulin receptor isoform X1
KO
K04527
insulin receptor [EC:
2.7.10.1
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk04010
MAPK signaling pathway
elk04014
Ras signaling pathway
elk04015
Rap1 signaling pathway
elk04022
cGMP-PKG signaling pathway
elk04066
HIF-1 signaling pathway
elk04068
FoxO signaling pathway
elk04072
Phospholipase D signaling pathway
elk04150
mTOR signaling pathway
elk04151
PI3K-Akt signaling pathway
elk04152
AMPK signaling pathway
elk04211
Longevity regulating pathway
elk04213
Longevity regulating pathway - multiple species
elk04520
Adherens junction
elk04910
Insulin signaling pathway
elk04913
Ovarian steroidogenesis
elk04923
Regulation of lipolysis in adipocytes
elk04930
Type II diabetes mellitus
elk04931
Insulin resistance
elk04932
Non-alcoholic fatty liver disease
elk04960
Aldosterone-regulated sodium reabsorption
elk05010
Alzheimer disease
elk05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
111161798
04014 Ras signaling pathway
111161798
04015 Rap1 signaling pathway
111161798
04066 HIF-1 signaling pathway
111161798
04068 FoxO signaling pathway
111161798
04072 Phospholipase D signaling pathway
111161798
04022 cGMP-PKG signaling pathway
111161798
04151 PI3K-Akt signaling pathway
111161798
04152 AMPK signaling pathway
111161798
04150 mTOR signaling pathway
111161798
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
111161798
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
111161798
04923 Regulation of lipolysis in adipocytes
111161798
04913 Ovarian steroidogenesis
111161798
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
111161798
09149 Aging
04211 Longevity regulating pathway
111161798
04213 Longevity regulating pathway - multiple species
111161798
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
111161798
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
111161798
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
111161798
04932 Non-alcoholic fatty liver disease
111161798
04931 Insulin resistance
111161798
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
elk01001
]
111161798
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
elk04090
]
111161798
Enzymes [BR:
elk01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
111161798
Protein kinases [BR:
elk01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
111161798
CD molecules [BR:
elk04090
]
Proteins
111161798
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
Insulin_TMD
fn3
Kinase-like
DUF4476
B2
Motif
Other DBs
NCBI-GeneID:
111161798
NCBI-ProteinID:
XP_022381471
UniProt:
A0A2Y9L682
LinkDB
All DBs
Position
Unknown
AA seq
1369 aa
AA seq
DB search
MGAGAGRGAATAPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTSCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTSEGLCCHSECL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG
CHQYVIHSNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGC
TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL
EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
RQAEDSELYELDYCLKGLKLPSRTWSPPFEAEGSPKHNQSEHEESAGECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFVPRPSRKRRALRDVANVTAAVPTAPGFPNTSTSTPTSLE
EHKPFEKVVNKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYVSARTMPEAKADDI
VGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRRHFALERGCRL
RGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIG
SIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGS
FGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVV
SKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAK
KFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVF
TTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCW
QFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMESVPLDRAS
HSQREEAGGRDGGSSLGLKRNYEEHIPYTHMNGGKKNGRILTLPRSNPS
NT seq
4110 nt
NT seq
+upstream
nt +downstream
nt
atgggcgccggggctgggcggggggcggcgaccgcgccgctgctggtggcggtggccgcg
ctgctgctgggtgccgcgggccacctgtaccctggagaggtgtgtcccggcatggatatc
cggaacaacctcacaaggttgcacgagctggccaactgctcggtcattgaaggacatttg
cagatactgttgatgttcaaaacgaggcccgaggatttccgagacctcagtttccccaaa
ctcatcatgatcactgattacttgctgctcttccgggtctatgggctggagagcctgaag
gacctgttccccaacctcacggtcatccggggctcgcgcctcttcttcaactacgcactg
gtcatcttcgagatggttcacctgaaggaactcggcctctatagcttgatgaacattacc
cggggctccgtccgcatcgagaaaaataacgagctgtgctacctggccaccatcgactgg
tcgcgcatcctggattctgtggaggataattacattgtgctgaacaaagacgacaacgag
gagtgtggggacatttgtccaggcacggcgaagggcaagaccagctgccctgccactgtg
atcaacgggcagtttgtcgagcggtgttggacacacagccactgccagaaagtttgtccc
accatctgcaagtcgcacggctgcacctcggagggcctctgctgccacagcgagtgctta
ggcaattgctccgagcccgacgaccccaccaagtgcgtggcctgtcgcaacttctacctg
gacggcaggtgcgtggagacctgcccgcccccctactaccacttccaggactggcgctgc
gtgaacttcagcttttgccaggacctacacaacaagtgcaagaactcccggaggcagggc
tgccaccagtacgtcattcacagcaacaagtgcatccccgagtgcccctctggttacacg
atgaattccagcaacctgatgtgcactccatgcctgggcccctgtcccaaggtctgccac
atcctggaaggcgagaagaccattgactcggtgacgtccgcccaggagcttcgaggctgc
actgtggtcaacggaagcctcatcatcaacatccgagggggcaacaacctggcagctgag
ctggaggccaaccttggactcattgaggaaatttccgggtatctgaaaatccggagatcc
tacgctcttgtgtcactttcctttttccggaagttacggctgattcgaggagagaccttg
gaaatcgggaactactctttctacgccttggacaaccagaacctaaggcagctttgggat
tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataatcccaaa
ctctgcttgtcagaaattcacaagatggaggaagtttcgggaaccaaggggcgccaggag
aggaacgacattgccctgaagaccaacggggaccaggcgtcttgtgagaatgaactcctt
aaattttcttacattcggacatcatacgacaagatcttgctgaaatgggagccatactgg
ccccctgacttccgagacctcctggggttcatgcttttctacaaagaggccccttaccag
aatgtgacagagttcgacgggcaggatgcgtgtggctccaacagctggaccgtggtggac
attgacccccctctgcggtccaatgaccccaagtcgcagaaccacccagggtggttgatg
cggggtctcaagccctggacccagtatgccatctttgtcaagaccttggttaccttttct
gatgaacgccgcacatatggggccaagagtgacatcatctatgtgcagacagatgccact
aacccttccgtccccctggatccaatctccgtttctaattcctcgtcccagattatcctg
aagtggaaacctccctcggaccccaatggcaacatcacacactacctggttttctgggag
aggcaggcggaagacagtgagctgtacgagctggattattgcctcaaagggttgaagctg
ccatcccggacctggtctccgccgttcgaggctgagggctccccgaagcacaaccagagt
gaacacgaggagtccgccggcgagtgctgctcctgccccaagacagactcccagatcctc
aaggagctggaggagtcctcttttaggaagacctttgaggattacctgcacaatgtggtg
ttcgtccccaggccatcgcggaaacgcagggccctcagggacgttgccaacgtgacagcg
gccgtgcccacagctccaggtttccccaacacctcgactagcacgcctacaagcctggag
gagcacaagcctttcgagaaagtggtgaacaaggagtccctggtcatctctgggctgcgt
catttcaccggctaccgtatcgagcttcaggcttgcaaccaggacgcccccgaggagagg
tgcagcgtggcggcctacgtcagcgccaggaccatgcccgaagccaaggcagacgacatc
gttggccctgtgacccacgaaatcttcgagaacaatgtcgttcacttgatgtggcaggag
ccaaaggaacccaacggtctgattgtgctgtatgaagtgagttaccgacgctatggtgat
gaggagctgcacctctgtgtctcccgcagacacttcgctctggagcggggctgcaggctg
cgcgggctaccgccggggaattacagcgtgcgagtccgggccacctccctggcaggcaac
ggctcctggacagaagccacctatttctacgtgacagattatttagatgtcccatcgaat
attgcaaaaatcatcatcggccccctgatctttgtctttctcttcagtgttgtgattgga
agtatttacctgttcctgcggaagaggcagccggatgggccgctgggaccgctgtatgcg
tcttcaaaccctgagtacctcagtgccagtgatgtgtttccatgttctgtgtatgtgccg
gacgagtgggaggtgcctcgggagaagatcactctcctgcgggagctggggcagggctcc
ttcggcatggtgtacgagggcaacgccagggacatcgtcaagggcgaggcggagacccgt
gtggcggtgaagacggtcaacgagtcggccagtctgcgggagaggattgagtttctcaac
gaggcctcagtcatgaagggcttcacctgtcatcacgtggtccgcctcctgggggtggtg
tccaaaggccagccgacgctggtggtgatggagctgatggcccatggggacctcaagagc
tacctccgctccctgcggccggaggctgagaataaccccggccgccctccccctaccctg
caagagatgattcagatggcggcggagatcgccgatgggatggcctacctgaatgccaag
aagttcgtgcaccgggatctcgcagctcgcaactgcatggtggcccacgatttcaccgtc
aaaattggagactttgggatgaccagagacatctatgaaacggattactaccggaaagga
ggcaagggtctgctccctgtgcggtggatggcaccggaatccctgaaggacggggtcttt
accacttcttctgacatgtggtcctttggcgtggtcctttgggaaatcaccagcttggca
gaacagccttaccaaggcctgtcaaatgaacaggtgttgaaatttgtcatggatggaggg
tatctggaccaacccgacaattgtccagagagagtcaccgacctgatgcgtatgtgctgg
caattcaatcccaagatgcggcccaccttcctggagatcgtcgacctgctcaaggatgac
ctgcaccccagctttccggaagtttccttcttccacagcgaggagaacaaggcacctgag
agcgaggagctggagatggagtttgaggacatggagagtgtccccctggatcgggcctcc
cactctcagagggaggaggccgggggccgggatggagggtcctccctgggcctaaagcgg
aactacgaggagcacatcccctatacccacatgaatgggggcaagaaaaacggacggatt
ctgactctgcccaggtcgaatccttcttaa
DBGET
integrated database retrieval system
