Esox lucius (northern pike): 105011979 Help Entry 105011979         CDS       T04894                                  Symbol hmcn1 Name (RefSeq) hemicentin-1 isoform X1   KO K17341   hemicentin Organism els  Esox lucius (northern pike) Brite KEGG Orthology (KO) [BR:els00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:els04990]     105011979 (hmcn1) Domain-containing proteins not elsewhere classified [BR:els04990]  EGF-like domain-containing proteins   hEGF / cEGF domain-containing proteins    105011979 (hmcn1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 Ig_2 ig V-set C2-set_2 TSP_1 EGF_CA G2F cEGF TSP1_spondin Receptor_2B4 Izumo-Ig FXa_inhibition EGF_3 TSP1_ADAMTS EGF Coilin_N hEGF Motif Other DBs NCBI-GeneID:  105011979 NCBI-ProteinID:  XP_010870816 LinkDB All DBs Position LG08:30761669..30927342 Genome browser AA seq 5628 aa AA seqDB search MGNRLDSFLLVQILLLVTVSSGLRTEDTIEEIPEGASTLAFVFDVTGSMYDDLVQVIEGA SKILEMSQSRTKRPLYNYALVPFHDPEIGPVIITTDPKKFQFELRELYVQGGGDCPEMSI GAIKIALEISLPGSFIYVFTDARSKDYKLTHQVLQLIQQKQSQVVFVLTGDCDDRAHIGY KVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQSSKVHLLSTDHYDGISNTWQIPFDPS LKEVTVALSGPGPDIEIYNPLGNLVGKNDNLTELLHIPNSAKVVNIKDPEPGMWSIKTSS EGRHSVRISGVSTIDFRAGFSRKPTLDFKMTSSRPVQGIPTYILLNTTGLFHPALADRLE LLSITGGVIKTLPVRYYPDTGRGRTSTGSIWNITEFVPPNEAFFLRVTGYDMDGFLFQRV SSVSYSSIVPDAPKVVMPPTTPGYYLQKGAISCQVDSLIPFTLRFSREGRRLGIDQLFSE SANALWELAQVTLKDEGFYECIAISSAGTGRSRTFLDVSEPPPAITVDGNVTVTPGSRAV LTCHVVSTVQFNLTWHRGGVDAQQDPNLHLLTNHSLELRNVGIAAAGWYECIAANDGGTS IERIYLNVQEPPRVTVNPQNQTFTTGQEVRIRCSAKGYPDPRLVWTHNGMFIMGSSRQRT TSDGSLLIRNMNQKDAGVYGCLASNVAGTDSDRSILTYIESPVVTVVQSEILIGLGETTV LACTASGIPKPEIKWYKGDLQLRPSSFMDMDPQVGTLTIKETQDVDAGDYTCVAVNLAGT SSPGKITLDVGSAPQFTREPSDVGSDIGSNVTLPCNAQGYPQPQVTWRREDNAPLFIRHT THSTITQNSAGDLQIRNLWVEDDTVYVCDAENQFGKIQARARVTVTGLVSPLIGHSPSVL SVIEEQQVTLPCVLLAGNPLPERRWLHNHGLVISSPYVTVRRDGSLHIERVRLEDGGDYT CLAENVLGFSNHTTTLNVYVMPTIQHGPQVFSTIEGTPVTLPCHANGVPVPDITWSKRGE LLNLGGPSFSLWSDGSLHITSPTGGESGEFVCTATNAAGYSSRKVHLTVYVRPRQIGGSG GAGGDGEALEVSVIVGEDVTLPCEVQSVPPPIITWAKERQLISPFSPRHTQLASGSMKIL ESRVSDSGLYVCVASNIAGNLTQNVLLSVLVPPSIQAGPRVMKVQVGHPVDLPCVVLGAP QPSLAWLKDGTSLAEGGAQYRIAPDGSLTLGQVGLSDEGTYTCVATNIAGEDQTSIQLQV QVPPVVDVLEPPFNSPHQERVANQRIAFPCPAKGIPTPVIKWLRNGQELTGNEPGLTIME DGTLLILASVSQLDNGEYVCMAANEAGTTEKKYQLKVNVPPNVHDSGLPNNVSVVLNLPA NLVCDVTGSPTPVITWYKDGLPVVPSSSVQILQQGKTLRLLKTTTADTGRYSCKAINIAG SSEKVFLLDVLVPPTIIGTSSSPEVSAVLNQEVNLECKVKGTPFPTIQWYKDRKLVFLGD PNLEVSNRDQNLKIKSARLGDQARYQCSVTNAAGKQTKDFNLSVYVPPTIKGGNVTSEVT ALLDTVVTLECEARGVPLPTITWYRNGEAILSSRQVQYVDRGHFLRIPRTQASDAGQFTC RVTSVAGTAEKNFELDVYLPPSIVGGQDTPTVRKVVLSDPLTLECKAEGHPPPTLTWLKD GIPVRNGESVSILERGRKIEILSIHMSDAGRYVCVATSVAGEKEMKYDVSVLVPPVVEGG DDVTDTTVVINNPLELECRATGTPSPAFRWFKDGQLIRQGDGVRVTANGRRLIISRPQIT DTGRFQCVATNDAGDHERDFNVAVHVPPSIRSTGLSERAVVLHKPIRFQCVHSGIPLPSL TWLKDGRPVDTSKEHLKLESAGRTLHISEARLEDAGKYTCVATNAAGEAQLHIRLSVHEP PSIPFSGETFNETIIAGYPTQLECKALGNPLPAITWYKDGRPLTSAAGVTILKRGQLLEI DRAQLSDAGLYRCIAVNVAGSVEVSHRLQVYVPPSISSRSGLVTVVVNNPASLECEATGI PLPSLTWLKDGSPVASLSESIQVLFGGRVLSLTSAQVTDTGKYTCVAINAGGEQQKDYDL TVYVPPNIMGEEVNATAMLGRVVELRCESDAIPPPTLSWRKDGRPFFRKPGLTVSEDGSV LKIDSAQVQDSGRYTCEATNIAGKTEKNYNLNVWVSPSIRGSEEVSSITVMEGNLITLVC ESSGIPPPSLVWHMDGSELKSDSRVRILSGGRQLQISSAERTDSASYTCTASNVAGNTTK EYTMQVYVRPSIRRSDRPEGNYITVTRGGDVTLQCEADGVPRPAVTWLKDGRPIIGQRGA QVLNEGRLLQIKDAKVSDTGRYTCVAVNVVGQADDKHDVSVHVPPSISGQNQDPENVSVV VKNPVALTCEASGIPLPAITWLKDGQAIKASSSVRVLSGGRSLRLMHAAVEDAGRYSCIV SNTAGEERKNFDLDILVPPSIVNEGTVHDTKVMEKHNVTLSCEVTGNPVPEITWLKDGES LGTDRRHQILSHGRFLQISGAQVSDTGRYSCLAHNSAGDRSRHFNVNVLVSPTIVGSGPE GSAEEVTVTLSSPTSLVCEVQSYPPAVITWFKDGKPFESSRNVRVLPGGRTLQIMNAQEE DAGKYTCVATNEAGDSLKNYEVKVYIPPQINKNDVPGMGLSPKEVKIKVNNTLTLECVAQ AIPTPSLQWYKDGQVLRADDHLNITANGRIVRIKQAQVSDTGRYTCVATNVAGEDEKDFD VNIQVPPSVQRPGGVRDPGSGGDVKDVVLNSPISLYCETNAVPPPTLTWYKDGRPLASSD KVLIMPGGRVLQIPRAQAEDSGRYTCVAVNEAGEDSIRYDVRVFLPPSIRGGGGDLPEEV VVRVNRSTVLECQVSGSPAPKVTWLKDNQPLSADGFHILLSNGRSLQVSNAQVTDTGRYV CVAVNLAGSAEKSFNLNVHVPPTIVGVSPENVTVVVNNFVSLTCEATGFPPPSLSWLKDK GPVQPHTNTLIMPGGRTLQILRAKMSDGGKYSCVATNPAGEARKPIHLSVFVPPSIRDSS GDTPVVVNVLVGNSVTLACESNAVPPPTITWLKNGRMVTESASLRILAEGQMLELKGAEV SDTGQYVCKAKNVAGQVDKNFHLNIYVPPSISGSVEEKVVETISNPVTFACDATGIPPPS LAWQKNGRTIENSESLELYILSGGSKLQISRSQLSDSGNYTCVASNVEGKARKSYHLTIQ VPPSISGSEIPGEVGVLLNDSVQLVCRAQGTPPPSIQWLKDGMALEAGLRGLRISPDGST LTLSGAQTSDSGKYTCVASNRAGEEDRIFNLNVYVPPAIEGNSDGPVELTTMLDSTVNIE CVASGSPPPQLNWLKNGLPLPVSSQTRVLSAGQVLRIARAQVSDGGIFTCVASNRAGVDN RHFNLQVHVPPRLDGAGSTEDVTVVRGNLASLLCIADGTPSPSMSWLREGETLVPDTHIK LLNLGTTVQIPQVRVEDTGRYTCWAVNTAGRASRHFNLKVLAPPRINGSGIAAEVSVVVN HVLELLCEATGIPTPTLTWLKDGRPLPHTDSLRLLRGGEVLRISSPQVEATGRYTCLANS PAGDDDKEFLVRVHVPPNIAGESTPQNMSVLQNRQVTLECKSDAVPPPTLTWLKDGKTLQ ASPRVRVLSSGRYLQINMAELGDGAQYTCVASNVAGKTTRQFNLAVNVAPIIAEGPDVVS VHIDQPVVLECVVSGVPAPRVSWRKHGAILAGTNPRYQFTEDGSLRIHSAQVTDTGRYLC MATNQAGTQRKRFDLQVYVPPSIAHGPTNITVTVNIQTTLSCEASGIPKPTVTWSKNGRS LNTDQNQNMYRLLSSGSLVVIAPTVEDTAYYKCIVSNEAGKDTRVIQLSVQVPPSIADEA TELVVTRLSPLVIGCTTSGVPEPTLHWSKDGMILPREGRGYSILPSGPLEITSAELSHTG HYSCVAENAAGSAHRHVQLTVQEIPVIQTHPSSLDVILNNPITLPCRATGSPWPTITWQK EGINIATNAGVFTVLPDGGLQISRAATADSGTYMCVAQNPAGTALGKIKLKVQVPPTISS QTQNYLVPLDSSVTLLCQAEGSPSPTVTWHKDGQPLSESVRQRFLSSGSLQIVFAQPGDT GRYTCTAVNTAGTSSLEMSLSVQIPPSIRGGEAEVSVVENSQAQLMCVAEGVPQPTLSWE KEGTPVSDAAGEYTVLPSGALVIDIAQPDDAGSYTCVASNTVGQDSRTVSLSVHTHPVFT ELPGDMALNKGERLLLVCGVAGIPPPKITWTFNNNIKPAHYNHVNGHSEMVIERVSKDDS GTYSCVAENRVGTIKSLAYVYVKEPPIIDGDFHPNRIEPLGGNAVLNCGVRGDPLPTIQW SKKGVNIQTSKRIHQLDNGSLAIYSTVNEDAGKYVCVATNDAGVVERIVTLTLQSSPSIT VEPEETVVDAGTTVLLNCHASGEPIPVIEWSRQGSPLIGNERFTILSNGSLRVTSAQIED TAEYECVARNLMGSVLARVTLTVRVHGGFSEWTAWGPCSVSCGVGAHRRLRQCNNPLPAN GGRHCQDSDIETRSCQGKPCPVDGNWSEWSSWEECSSTCGQGNRTRVRTCTNPPAQHEGR PCEGKAVEAVVCNIRPCPVSGNWGTWLPWSSCSETCSKGMQTRVRLCNNPPPSFDGPQCE GTDSQTQLCEERQCPVDGNWSSWVSWGTCSVSCGGGTRQRTRLCTSPAPQHGGRLCEGVD MHIDFCNSDLCPVHGNWGPWSSWGSCSRTCNGGQMRRYRTCDNPRPANGGRACAGADSQI QRCSTANCPVDGNWGAWQAWGDCSASCGGGERTRVRLCNNPSASKQGHPCPGDFTQLSRC NSQACPGGPRRAKGSIIGNINDVEFGIAILNATISDNQSGGRFIQAFISNVPRSLGPAMR KIISILNPIYWTTAQELEEAVNGYSLTSGVFRRETQVEFATGEILRMTHVVRGMDSDGTL LLDVVVNGHVLQLPSNADLSIKDYTEDYIQTGPGQLYALSDRMFSVDRVSVPYSWNHTIT YDPEKGKMPYLVETLYASAISTHYHPLEEVLEYTIHATITKGDRSNQCPRGFRLDPAGPY CSDEDECTEGNPCSHACHNAMGTYYCSCPRGLTISADGRTCQDIDECSLGGHMCHGGQDC ENTIGSYRCVMHCGRGFRRTADGHSCQDINECQEFNPCNQHCLNTIGSYRCACEPGYQLR NRRCIDINECRQRVCRSDQQCKNTRGSYTCIDLCPTGMTKGANGTCLDIDECRDGTHQCR YNQICENSRGSYHCSCPRGYRSQGVGRPCLDVNECERSPQPCAYRCLNTLGSFECVCPPG RHLLGDGKSCAGLERLSPSYESFSYGYHSSQASSERSSFRRQYHSLASQSYPSYAATGGR YRQRSRKEALFCPQGYEARVGICLDINECEVKDTCQHECMNTPGSHRCLCPAGYRLMTNG KTCQDIDECLEQNIQCGNNRMCFNMRGSYQCIDTPCPPNYQRDPATGFCLKNCPPNDLEC ALSPYALEYKLLSLPFGIAANQDLIRLVAYTQDSVVHPRTSFLVVDEDMMLPFALRDENL KGVLFTTRALREPHTYRMKVRSLSYSADGGIEYQTTFIVYIAVSAYPY NT seq 16887 nt NT seq  +upstreamnt  +downstreamnt atgggaaatcggcttgattcatttttgctggtacagatacttctcctggtcactgtatcc tccgggctcagaactgaggacacaatagaggagatcccagagggagcgtcaaccctggcg tttgtctttgatgtcactggctccatgtacgatgatctcgtgcaggttattgagggggca tccaagattctggagatgtcgcagagtagaactaagagaccactctataactatgcattg gtgccattccacgacccagagattggaccggtaatcatcactacagatccaaagaagttc cagtttgaactcagggagctgtatgtccagggaggtggagactgcccagagatgagcatt ggtgccatcaagattgccctggagatctccctgccggggtcctttatttatgtctttaca gatgccagatccaaagattacaaactaacgcaccaagtcctgcagctaatccagcagaaa caatctcaggttgtgtttgtgctgacaggggattgtgatgaccgagctcacattgggtac aaggtctacgaagagatcgcctccaccagctctgggcaggtgttccatcttgacaagaaa caagtcaatgaagtgttgaaatgggtggaagaggcggtgcagtcatccaaggtccatctg ctgtccacagaccactacgatgggatcagcaacacctggcagatcccatttgaccccagt ctgaaggaggtcactgtggccctcagtggccctggacctgacatcgagatatacaacccc ttggggaaccttgtcggaaagaacgataatctgacggaactgctgcatattcccaactct gcaaaggtcgtcaacatcaaggacccggagcctggaatgtggtccataaagacatcaagt gagggcagacactctgtacgaatatctggtgtaagcactattgacttccgggctggattt tccaggaagcccaccctggactttaagatgacctctagtcgacccgttcaaggtatccct acctatatcctattgaacacaactgggctgttccatccagcgctagcagatagactggag cttctgtcaataaccggtggtgtgattaaaaccctcccagtgcggtactaccctgacact ggtaggggtagaacctcgacaggaagcatctggaacatcacagaatttgttccgcccaat gaggccttcttcctacgggtcacaggatatgacatggatggcttcctgttccagagggtc tccagtgtgtcctattccagtattgttcctgatgcacccaaggttgtgatgccccccacc accccagggtactacctccagaaaggggccatatcctgccaggtagacagcctcatcccc ttcaccctccgcttcagccgggaagggagacgcctcggcattgaccagctatttagcgag tcagccaatgccctgtgggagctggctcaggtgactttgaaggatgagggcttctatgag tgcattgccatcagcagtgccggaacaggacgctccagaaccttcctggacgtttcagag ccaccaccagccatcacagtggacggtaacgtaactgtaactccaggctccagagctgtc ctgacctgtcatgtggtcagtacggtccagttcaacctgacctggcacagagggggtgtg gacgcacaacaggacccaaaccttcacctcctgaccaaccactccctggagttacgcaac gttggcatcgccgctgctggctggtatgagtgtattgccgccaacgatggaggaacctcc attgaacgcatctacctcaacgtgcaagagccaccccgggtgacagtgaacccccaaaac cagacctttaccacaggacaggaagtgaggatcaggtgctcggccaaaggttaccctgac cccagactagtctggacccacaacggcatgttcatcatgggctccagcagacaaaggacg acctccgatgggagtctgcttatcagaaacatgaatcagaaggatgctggggtgtatggg tgtcttgccagcaatgtggccgggacagattcagacagatccatcctcacctacattgaa tcccctgtggtgaccgtggtgcagagtgagattctgattggtctaggtgagaccaccgtc ttggcttgcaccgcctctgggatccccaaacctgaaatcaagtggtacaaaggtgacctg cagttaaggccatcctccttcatggacatggacccccaggtagggactctgacaatcaag gagacgcaggacgttgatgcaggagactacacctgtgtagctgtcaaccttgctgggacg tcctcacctgggaagatcaccctggatgtaggatctgcaccccagtttaccagagaacca tccgatgtggggtcagacattggctctaacgtgacactgccgtgcaatgcgcagggttac cctcaacctcaggtcacttggaggagggaggacaacgcaccccttttcattagacacacc acacacagcaccataacgcagaacagtgcaggagacctgcaaatcaggaatctgtgggtg gaagatgatacagtgtatgtgtgtgatgccgagaaccagtttgggaaaatacaggcccgt gccagagtcactgtcaccggactggtgtccccattgatcggccacagcccaagtgtgttg agtgtaattgaggagcagcaggtgactctgccttgtgtgctgctggctggtaaccctctt cctgagagacgctggttacacaaccacgggctggtgatctcaagcccctatgtgacggtg cgtagggatggcagtctgcatatagagcgtgttcggctggaggatgggggggactacacc tgcctggctgagaatgtgctggggttcagcaaccacaccaccaccctcaacgtctacgtg atgccaactatacagcatggtccgcaggtcttcagcaccatagaaggcacccctgtcacc ttgccatgccatgctaatggtgtacccgtgcccgacatcacctggtccaagcgaggggag ctgttgaacctgggtggtccttctttttctctgtggtctgatggcagtctccacatcacc tcccccactgggggggagtctggggagttcgtctgcacggccaccaacgcggcaggctac agctccaggaaggtccatctcaccgtgtacgttcgtcccaggcagatcgggggctccgga ggggccggaggcgacggcgaggccctggaggtgtctgtcatcgtgggggaggatgttacc ctgccctgtgaggtccagagtgtcccccctccaatcatcacttgggccaaggagaggcag ctcatatcccccttctcacccagacacactcagctggcctctggttccatgaagatcctg gagagtagggtgtcagacagtggtctgtacgtgtgtgttgcctccaacatcgcggggaac ctcacccagaatgttctcctcagtgtccttgtgccccccagtatccaagctgggccacgg gtgatgaaggtgcaagtggggcatcctgtagacctgccctgtgtggtgctgggggcaccc cagccttccctggcctggctaaaggatggcacctccctggcggagggcggggcacagtac aggatcgcccccgatggctctctgactctaggtcaggtggggctgagtgacgaggggacc tatacctgtgtggccactaacatcgctggagaagatcagaccagtatacagttgcaggtg caagttccccctgtggtggatgtgctggagcccccattcaacagcccccaccaggagaga gtggccaaccagcgcatcgcctttccctgtcccgccaaaggcattcctacgcccgtcata aagtggttgcgtaacgggcaggagctgacagggaacgagccaggtctgaccattatggag gacggaacccttctcatcctagcatcggtttctcagttggacaacggagagtatgtctgc atggccgccaacgaggctggcaccactgagaagaagtaccagctcaaagtcaacgtgcca cccaacgtccatgactctgggttaccgaacaatgtgtcagtggtactgaatctacctgcc aacctggtgtgtgatgtcacaggaagtcccaccccagtcatcacctggtacaaggatggt cttcctgtggttcccagtagcagtgttcagattctccagcaaggaaagaccctgaggtta ctgaagaccaccacagcagacactggacgttatagctgcaaggccatcaacatcgcagga agttcagagaaggtcttcctcctggacgtgctggttccccccactatcattgggacaagc tcctctcccgaagtgtcagcagtgctaaaccaggaggtcaatctggaatgtaaggtcaaa ggaactccatttcccacaatccagtggtacaaagacaggaaactggtgttcctgggtgac cccaacttagaggtcagcaacagggatcagaacctgaagataaagagtgctcgtctggga gaccaggcacgctaccaatgtagtgttactaatgcggcgggcaaacagaccaaagacttc aacctcagtgtctacgtccctcccaccataaagggtggcaacgtgacctcagaggtaact gccctcctggatactgtggtaacactggagtgtgaggcacgtggggtgccgttgcccacc atcacctggtatcgcaatggagaggccatcctgtccagccgccaggtgcaatacgttgac cgaggtcatttccttcggatcccacgcacccaggcatcagatgctggtcagttcacctgt agggttaccagtgtggccgggactgcagagaagaattttgagcttgacgtttaccttcct ccctccatcgtggggggtcaggacactcctacagtgaggaaggtggtgctcagtgatccc ctgaccttggaatgtaaagctgaaggtcaccccccccccacactgacctggctgaaggac ggcattcctgtccggaatggggagagcgtcagcattctggagcgaggccgtaaaatcgag atcctctccatccacatgtctgacgctgggcgctatgtctgcgtggcaaccagcgtcgcc ggggagaaggagatgaagtacgatgtcagtgttttagttccccctgtggtggagggaggg gatgatgtcacagacaccacggttgtcattaacaaccctctagagctagagtgtcgtgct acgggtacaccttcacctgccttcaggtggtttaaggatggtcaactaatcaggcaaggt gacggagttcgggtcacagctaacggccgtcggctgatcatctctcggccccagatcaca gacacaggacgcttccagtgtgtggccaccaatgacgccggggaccatgagagggacttc aatgtggccgtccatgtccctccttccatccgatccactggtctctctgagcgtgccgtg gtcctccataagcctatcagattccagtgtgtccacagcggcattcctcttcccagtctc acctggctcaaagatggccgccctgtggacacttccaaggagcacctgaagcttgagtcg gctggtaggactctacacatatcagaggccagactagaggatgctggaaaatatacctgt gtcgcaaccaatgcagcaggagaagcccagctacacatccgcctcagtgttcatgagcct ccaagcattcctttctctggtgagacctttaatgagaccatcatagcaggttaccccacc cagttggagtgcaaggccttagggaatccactgcctgccattacttggtacaaggatggt cgaccactaaccagtgccgctggagttactatcctcaaacgtggtcagctgctggagatt gaccgtgctcagctgtctgacgctgggttataccgttgtatagcggtcaacgtggccgga tccgtagaggtctctcacaggctgcaggtttatgtgcccccttctatttctagccgcagt ggcctagtgacggtggtggtgaacaaccctgccagcctggagtgtgaggccactggcatt cctctgcccagccttacttggctcaaagatggcagcccggttgccagtctgtcagaaagc atacaggtgttgtttggtggtagagtgttgagtctgactagtgcccaagtcactgacaca ggcaagtatacctgtgttgccattaacgcaggaggagagcagcagaaagattatgacctt acggtgtatgttccaccaaacattatgggagaggaggtgaatgccacagcaatgctgggt cgagtggtggagttgcgttgcgagagcgatgccatccctcctcccacattgtcatggcgg aaagatggccgtccattttttaggaagccgggactgaccgtgtctgaggacgggagtgta ctgaagattgacagtgctcaggtgcaggattctggcagatacacctgtgaggccaccaac attgccggcaagacagagaaaaactacaatctcaatgtctgggtgtctcccagtatccgc ggttcagaagaggtgtcttccataacggtgatggagggaaacctgatcaccctggtgtgt gagtccagtggcattcctcctcccagcctcgtctggcatatggatggttcggagttgaag tcagactcaagggttcggatcctgtctggtgggcgtcagctccagatctccagtgctgaa aggacagactctgcttcctacacatgtactgcctccaatgttgccgggaatacaaccaag gagtacaccatgcaggtgtacgtccgcccttccatcagacgcagcgatcggccggaagga aattacatcactgtgaccagaggcggagatgtcaccctacagtgtgaggctgacggcgtg ccacgcccggcggtcacatggctgaaagacggtcggccgattatagggcaacgtggggcg caggtactgaatgaggggcggctcctacaaatcaaggacgccaaggtttcggacacaggg cggtacacgtgtgtggcagtgaatgtcgtgggacaggccgacgacaagcatgacgtcagc gttcatgttcccccaagtatcagcggtcagaaccaggacccagagaatgtaagtgtggta gtgaagaaccctgtggcgctgacctgcgaggcctctggcatccctcttcctgctatcacc tggctaaaggatggccaggcaataaaagcctccagctctgtccgtgtcctctcaggaggg cggagtcttcgtctgatgcatgcagcagtggaggatgctgggagatacagctgcatagtg tccaacacggccggagaggagaggaagaactttgacctggacatcctggtcccccctagc attgtgaatgaaggcacagtgcatgacaccaaggtcatggagaaacacaatgtgacactg agctgtgaagtcacaggtaacccagtgcctgagatcacctggctgaaggatggagagtca ctgggaacagacagacgtcaccagatattgtctcacggaaggttcctccaaatatctggc gcccaggtgtcagacacaggcagatacagctgcttggcacacaacagcgcaggagaccgt agcagacacttcaacgtcaatgttctggtgtctcccaccatcgtcggctcgggtcctgag ggttcagcagaggaggtgaccgtcaccctgagcagccccacgtctctggtgtgtgaggtg cagtcttacccccccgctgttatcacatggttcaaggatgggaaaccgtttgagtccagt cgcaatgtcagagtgctgccaggtgggcgaaccctgcagatcatgaacgcccaagaggag gatgctgggaagtacacctgcgtggccactaatgaggccggggacagcctgaagaactac gaggttaaagtttacattcctccccagatcaataaaaacgatgtcccaggtatggggctg tcccctaaagaggtcaagatcaaggtcaacaacaccttgaccctagagtgtgtggcccag gccatccctacaccctccttgcagtggtacaaagatggacaggtgctgagggcagatgat cacctgaacattacagccaacggccgtattgtcaggatcaaacaggctcaggtgtccgac actggacgctacacctgcgtcgcaaccaacgtggctggggaggatgagaaggactttgat gtaaatatacaagtcccccctagcgtccagcgtcctgggggggtgagagacccaggcagt gggggtgatgtaaaggacgtggtgctgaacagccctatctctttgtactgtgagaccaac gctgtgccaccaccaactctcacctggtacaaagatggacgcccactggcctccagtgac aaagtgcttataatgcctggtgggcgcgtattacagatccccagggctcaggcggaggat tccggaaggtatacatgtgtggcagtgaacgaggcgggagaggactccatccggtacgac gtccgagtgttcctgcccccatcgatccgcgggggaggcggggatctacctgaggaggtg gtggtccgggttaataggagcacagtgttggagtgccaggtgtctggtagccccgcccct aaggtcacctggctgaaggacaaccagccccttagcgctgacggattccacatcctgctg tcaaacggacgctccttgcaggtgtcgaacgcccaagtgacggacacaggtcgctacgtg tgcgtggccgttaacctggcgggaagtgccgagaaatccttcaacctcaacgtacatgtc cccccaaccatagtgggtgtcagcccagagaatgtgacagtggtggtcaataactttgtg tctctgacgtgtgaggccacagggttcccccctccctctctgagttggctcaaagacaag gggccagttcagcctcataccaacacactcatcatgccaggtggacgcaccttgcagatc ctgagggctaagatgtctgacggggggaagtacagctgtgtagccacaaaccctgccggg gaggccaggaaaccaatccacctctcagtgtttgtgcctcccagtatcagggacagcagt ggggacactccggttgtggtgaatgtgcttgtgggtaactcagtgaccctggcatgtgag tctaacgctgtgcctccccccaccatcacctggttgaagaatggccgaatggtgacagag tctgccagcctccgcatcctggcagagggacagatgctggagctgaagggggccgaggtg tctgacactggccagtatgtctgcaaggccaagaatgtggctggacaggtggacaagaac ttccacctaaacatctacgttccccccagtataagtggttcagttgaggagaaggtagtg gagaccatcagtaaccctgtgaccttcgcctgtgacgctacgggcatcccccctcccagt ctcgcctggcagaaaaacggtcggaccatcgagaactcagaatctctggagctctacatc ctgtctggaggcagtaagctgcaaataagccgctcccagctctcggactctggaaactac acctgtgtggcctccaatgtggaaggcaaggctcgcaaaagttaccatctcaccatacaa gttcctcccagcatctcaggttcggagattcccggtgaggtgggggtgctgctgaatgac agtgtccagctggtgtgccgtgcccagggaacaccgcccccatccatccagtggctgaag gatggcatggcccttgaggcagggttaagaggactcaggatcagtccagatggcagcact ctcaccctgtccggagctcagacctctgacagtggcaagtacacttgtgtagccagcaac agggcaggagaggaggaccggatattcaacctcaatgtgtatgtacctcctgcgattgaa gggaacagtgacgggcccgtggagttgaccaccatgctagacagcaccgtcaatatagag tgcgttgcttcgggatcgcctccaccacaactcaactggctgaagaacggcctgcctctc cctgtctcttcacagacacgcgtgctgtctgccggacaggtgctcaggattgccagagct caggtttcggacggcggcatctttacctgtgtggcctccaacagggctggtgtggacaac agacacttcaacttacaggtgcacgttcccccccgcctggacggtgcgggcagtacagag gacgtgacggtggtgagagggaacctggcttcactgctgtgtatagctgatgggaccccc agcccctccatgtcttggctgagggagggggagaccttggtccctgacacccacatcaag ttgctgaacctgggcaccaccgtgcagatccctcaggtcagagtggaggataccggacgc tacacatgttgggctgtcaacacagcaggccgagccagccgccactttaacctcaaagta ctggcccctccccgtatcaacggttcgggcatagcagccgaggtgtctgtggtggtgaac catgttctagagttgctgtgtgaggccacaggaatccccaccccgacacttacctggtta aaagatggacggccgctaccccacacagacagcctgcgcctcctcagaggaggggaggtg ctcaggatctcctcgccgcaggttgaggccacagggaggtacacctgtctggccaacagt cctgcaggagacgacgataaagagttcctggtccgagtgcatgttccccctaacattgca ggggagagcactccacagaacatgtcagtgctgcagaacagacaggtgactctggagtgc aagtctgacgctgtccctcccccaacactcacctggctcaaagatggcaagacactccag gcatcccctcgcgtgcgtgtcctgtccagtggacgttacctccagatcaacatggctgag ctgggggatggggctcagtacacctgtgtagccagcaacgttgctggcaagaccacacga cagtttaacctggcagtgaatgttgctcccatcatagcggagggtcctgatgtagtgtcc gtccacatagaccagcctgtggtgttggagtgtgttgtgagtggagttcctgctccccgc gtgtcctggagaaaacatggagctatattggcaggaaccaaccccaggtaccagttcacg gaggatggctctctccgcatccactcagcccaggtaactgacacaggacggtacctgtgt atggccaccaaccaggcagggacccagcgcaaaaggttcgacctgcaggtctacgtgcca ccctctattgcccatggtcccaccaacatcacagtgacagtgaatattcagaccaccctc tcctgtgaggcgtctggcataccaaaacccacggtcacctggtccaagaacggtcgatca ctcaacactgaccagaaccagaatatgtacagattgttgtcgtcgggttctctggtggtc atcgcacccacggtggaggacacggcttactacaagtgtatcgtgtctaacgaggccggg aaggacaccagggtcatccagctctctgtccaggttcctccctccatagcagatgaagcc actgagctggtagtgacaagactgtccccgctggtgattggatgcactacgtcaggcgtc ccagagcccaccctgcactggagcaaagacggcatgatactcccaagggaggggagaggc tacagcatcctgccatcaggcccattagagatcacatctgcagagctgagtcatacagga cactactcctgtgtggccgagaacgcggcaggctccgcccatcgccacgtccagctcact gtacaggagattcctgtgatccagacccacccctcttctctggatgtgattttgaacaac cccattacccttccctgcagagccaccggctccccctggcccactatcacctggcagaaa gagggcatcaacattgctactaacgcaggtgtgttcaccgtgctgcctgatggtggcctg cagatctccagggccgcaacagcagactcaggaacatacatgtgtgtggcccagaacccc gctggcacagccctgggcaaaataaaactcaaagtacaagtccctccgacaatcagctcc cagacccagaactaccttgtgcccctggattcctctgtcaccctgctgtgccaggctgaa ggttctccctcgcccaccgtgacctggcataaagacgggcagcctctcagcgaatctgtg cgccaacggttcctcagctcggggtctctgcagatagtgttcgcccaacctggcgacacg ggccgatacacctgcactgcggtgaacacggctggcacaagcagcctggagatgagcctt agcgtacagatccccccctctatccgaggaggggaggcagaggtttctgtagtagagaat agccaggcccagctgatgtgtgtggcagagggggtcccacaacccaccctgtcctgggaa aaggaggggacacctgtgagcgacgctgctggggagtacactgtccttccctctggggcg ctcgtcattgacatcgctcagccagatgatgcaggcagttacacctgtgtagccagtaat acagtaggtcaggacagtcggacggtcagtctttcagtccacacccaccctgtcttcact gagctacccggagacatggccctgaataagggagagcgcctcctactggtctgtggggtc gctggcatcccacctcctaaaatcacttggactttcaacaacaacattaaaccagctcat tacaaccatgtgaacggccatagtgagatggtcatcgagcgggtctccaaagacgactca ggcacctactcctgtgtagctgagaaccgtgtgggaaccattaagtccctggcctatgtc tatgttaaagagcctcccatcattgatggggacttccatccaaaccgcattgaaccactg ggcggtaacgctgtcctgaactgtggggtacgaggagaccccctgcccaccatccagtgg agcaagaagggagtcaacattcagaccagcaaacgcatacatcagctggacaacggctct ttggccatctacagcactgtgaatgaagatgctgggaagtatgtgtgtgtggccaccaat gatgctggggtggtcgagaggattgtcacacttaccctgcagagttctccctctatcaca gtggagccagaagagacagtggttgacgctggcaccacggtgcttctgaactgccacgca tcgggggagcccatacctgtcattgagtggtcccgccaggggagccctctaataggcaac gagcgcttcaccatcttgtccaatggctctctgagagtcaccagtgcccagatagaggac acggccgagtacgaatgtgtggccaggaacctcatgggctctgtgctagccagagtaact ctcactgtacgagtgcatggagggttctcagagtggacggcctggggcccctgcagtgtg tcctgtggtgtcggggcccatcggagattgaggcagtgtaacaaccctctcccagccaat ggggggcgtcactgtcaagactcagacatagaaacacgcagctgccagggcaagccttgt ccagtggacggtaactggtcagagtggtcatcgtgggaggaatgttcttctacctgtggt caggggaacagaactagggtgcgcacctgtaccaaccccccagcgcagcacgagggaaga ccatgtgagggcaaggcagttgaggccgttgtgtgtaatatcagaccgtgtcctgtgtcg ggtaactgggggacctggttgccatggagttcgtgcagtgagacatgcagtaaagggatg cagaccagggttcgtctgtgcaacaatccccctccgtcatttgatgggccacagtgtgaa gggactgactcacagacacaactctgtgaggagagacagtgtcctgtggatgggaattgg tcttcgtgggtgagttgggggacctgcagcgtctcctgcgggggaggaaccagacagcgc acacgactttgtaccagtcccgctccccagcatgggggcaggctatgtgagggtgtcgac atgcacattgacttctgtaacagtgacctatgccctgtccatggtaactggggtccatgg agtagctggggcagctgcagcaggacgtgtaatggaggacagatgagacgctacagaaca tgtgacaaccccaggcctgccaatgggggcagagcatgtgctggggcagactcacagatc cagaggtgcagcacagccaactgccccgtggatggtaactggggggcatggcaggcctgg ggagactgctctgcctcttgtggagggggagagagaactcgtgtcagactttgtaataac ccgtcggctagcaaacaaggccatccctgccccggagatttcacccagctgtccaggtgt aacagccaggcttgtccaggcgggcccaggagggcgaaaggcagtatcataggtaacatc aacgacgtagagtttggaatcgccatcctcaatgccaccatctctgacaaccaatcagga ggcaggtttatacaggcctttatctccaatgtgccccggagcctaggtccggccatgaga aaaattatctccatcctgaaccctatctactggaccacggctcaggagctagaggaggct gtcaatggttactctttgaccagtggggtcttcagacgggagactcaggtggagtttgcc acaggtgagatcttgaggatgacccacgtggttcgggggatggactcggatggaacgctg ctattggatgtcgtggtgaacggacacgtcctgcagctgccctctaatgctgacctcagc atcaaggactacacagaagactacatccagactggtccaggccagctctatgctctgtct gaccggatgttcagtgtagaccgggtcagtgtgccctactcctggaaccacaccattacc tacgacccagagaagggcaaaatgccctacctggtggagacactctatgcctcagccatc agtacccactaccaccccctagaggaggtcttggaatacactatccacgccaccatcact aaaggagatcgtagtaaccagtgtccacgcggtttcaggctggaccctgcagggccctac tgctctgatgaggatgagtgtacggaggggaacccatgttctcacgcctgtcacaacgcc atgggaacctactactgctcctgtcctcggggactcaccatctctgctgatggcagaact tgtcaggacattgatgagtgttctctgggtgggcacatgtgccatggtggacaagactgt gagaacaccataggctcttaccgctgtgtgatgcactgtgggaggggcttcaggaggaca gctgatggacatagctgccaagacattaatgagtgccaggagttcaacccatgcaaccag cactgtctgaacactattggcagctatcgatgtgcgtgtgagcccggttaccaactcagg aaccgccgctgcatagacataaacgagtgcaggcaaagggtgtgtcgttccgaccagcag tgtaaaaacactcgaggcagctacacttgtattgacctgtgccccacaggcatgactaaa ggggccaatgggacatgtctggacattgatgagtgcagagacgggacccaccagtgcaga tacaaccagatctgtgagaacagcagagggagctaccactgtagctgcccccggggttac cgctctcagggtgtaggacgcccgtgtctggacgttaacgagtgcgagcgttcaccccag ccctgcgcctaccggtgcctcaacacgctgggcagcttcgagtgtgtttgcccgccgggg cgccacctgctaggggatgggaagtcctgcgccgggctggagaggctctcacccagctac gagagcttttcgtacggctaccactcctcccaggcctcttccgagcggagctccttccgg cggcagtaccacagcctggcctcccagagctacccctcctatgctgccacgggggggagg tataggcagcgtagccgcaaggaggccctgttctgtccacaggggtacgaggccagggtc ggcatttgcctagacatcaacgagtgtgaggtgaaggacacatgtcagcatgagtgtatg aatactccagggagccacaggtgtctgtgccctgctggctaccgccttatgaccaacggc aagacctgccaagacatagatgagtgtttagagcagaacatccagtgtggaaacaacagg atgtgctttaacatgagaggaagttaccagtgtatcgacacaccctgcccacccaactac cagagagacccagcaacaggattctgcctgaagaactgcccgcccaacgatctggaatgt gccctgagcccttacgcgctggagtacaagctgctgtccctccccttcggcatagcagcg aatcaggaccttatccggctggtggcgtacacacaggacagcgtggtgcacccgcggact tccttcctagtggtggacgaggacatgatgctacccttcgccttgcgagacgagaacctg aagggggtgctgttcacaacccgggccctcagagagccccacacctaccgaatgaaggtc cgctccctgtcctacagcgccgacggcggcatcgagtaccagaccaccttcattgtctat atcgctgtctccgcctacccctactga

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