Eublepharis macularius (Leopard gecko): 129330004
Help
Entry
129330004 CDS
T09084
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc00310
Lysine degradation
emc01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
129330004 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
emc03036
]
129330004 (DOT1L)
Enzymes [BR:
emc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
129330004 (DOT1L)
Chromosome and associated proteins [BR:
emc03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
129330004 (DOT1L)
HMT complexes
Dot1-containing complex
129330004 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
129330004
NCBI-ProteinID:
XP_054835797
UniProt:
A0AA97JEC7
LinkDB
All DBs
Position
5:11185501..11275081
Genome browser
AA seq
1767 aa
AA seq
DB search
MGERLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDKEFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGQIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVQ
ESKDDGAEEEKNPGANTVKKPSPSKARKKKLSKKGRKMAGRKRGRPKKMNVVNPERKTKK
SQTALELLHAQAVSQTCSSSPQDAYRSPHSPFYQLPPKVQRHSSNQLLVTPTPPALQKLL
DSFKIQYMQFMAYMKTPQYKENLQQLLEQEKEKNTHLMGKAQQLFTHCQAQKEEIKRLFQ
QKLDELGVKALTYNDLIQAQKEISAHNQQLKEQTKQLEKDNGELRNQSLQLLKARCEELK
LDWSTLSLENLLKEKQALKNQISEKQKHCLELQISIVELEKSQRQQELLQLKSCMPPDES
LPVQPRHKNHLNREPEPDHSLFQLELECPKFPVPHINGMSPELSMNGHATPYEVHHALSR
PSSKQSTPQYATSHLDQDIVPCTPNHNCRQKPDKASSLSLPDYTRFSPAKIALRRHLNQD
QTGSAKLTTNENHHRTEHIKENGITFPSPTIPNGIKMSPQEPRPSSPAAVPVANEKALRE
RTPANNGETITSLPISIPLSTVQPNKLPVSIPLASVVLPSRVEKVRNTPSPVHQNRDSFS
TLDKQCGASSHNGMSSVAANKSFTLATSGFSYTTGSGLANGTLSNSPAQLNHTVDHAALE
DVSSSGSLFSSAGSRSSTPQHPSLLMMPSRNSGQNSPAHQHSASPRMNGASQGLGGVLQY
MDSQKVFTEGTRGDAQADAAFSDPESEGKRRIIFTISPATGTIKHSPSSKHSSLTASIRM
ECGQAYVQDGKKRGRRKRSSTGTPNMNSGVSPKRKSLPAVAGLFAQPSGSPLNISSMVSN
INQPLEITAISSPENSLKNSPVPYQDNDQPPVLKKEKPIAQTNGIHYSPLTSDEEQGSED
DHNSTRIERKIATISLDSKSPQKPMESSISLAGRKQASENMNSSKWKSTFSPISDINLTK
TTDSSLQAPSSLSQNSLFTFRPSSEDTGDGPKVAAHSRKHMAMSATGTEGLHQNTSSMNG
FAYSGGLSADIGLHSFIDGALLPHKTNDATTLGSSSLGFLVQRNKEPGVSEANPFLSKRQ
LESLGALKGEDLNWPGAKGKEAGELNVRLGGSSEKALVLHNGKTSKGREREAELKNGHNL
FISATAAVPSGGLLNGKSLATSVSAAGSLAGPAVSAQAHHPFLNSLTAGSQFPLGPVALQ
ANLNSVTNSSVLQSLFNSMPAAAGLVHVSSAATRLTNSHAMGGFSPGVTGGTVGGIFNHV
VPCASSSSSSSTPSSSTPSFSSSSSAPLHFGAALSNSSVSSCAILNLNPLQVAASTSSFH
VPPNVVTSSETQPAQPLHRAMVQPSLLTPPPPPPPPNVSLPPPPPLRGSSNSESSVLLQS
LSSLQTAEAFLPPSSTANAALSIKLASLQHKPSRPTFTIHHPPLPRMALAQATPANPQSN
SAAAPAMWVSLGMQSPYASHLSGVKPR
NT seq
5304 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagaggctggagctccggctcaagtcgcccgtcggagccgagccggccgtctac
ccctggcccctgcccgtctacgacaaacaccacgatgctgctcatgaaatcattgagaca
attcggtgggtctgtgaagaaattccggacctcaagcttgctatggaaaactacgtttta
attgactatgatactaaaagctttgaaagcatgcaaaggctttgtgacaaatacaatcgc
gccattgacagcattcaccagttgtggaaaggaaccacccagcccatgaaactgaacacg
cgcccctccaacgggcttctccgccatatccttcagcaagtgtataaccactcagtaacg
gacccagaaaaactcaacaactatgagcccttttctccagaagtgtacggagagacttcc
tttgacttggtggcccaaatgatagatgagatcaaaatgacagaagatgatttgtttgtg
gacttgggcagtggtgtgggtcaagttgttctgcaagttgctgcagccacaaactgcaaa
catcactatggggtggagaaagctgatattcctgccaaatatgcagagaccatggacaaa
gaattcagaaaatggatgaaatggtatgggaaaaaacacgcagaatacacactggaaaga
ggtgatttcctctcagaagaatggcgagagagaatcgctaacacaagcgttatttttgtg
aataattttgcctttggacctgaggtggatcaccagttaaaggaacgatttgcaaacatg
aaggaaggtggccaaattgtatcatcaaaaccgtttgcaccgctaaacttcagaataaac
agtcgaaacttgagtgatattggcactataatgagagttgtggaattatcaccactgaaa
gggtctgtttcatggaccgggaaaccagtttcttactacctgcatactattgatcgaacc
atacttgaaaactacttctctagtctcaaaaatccaaaactcagggaggaacaagaggca
gctaggcgccggcagcagagagagaacaagagcaacacgacaaccccaactaaagtccaa
gaaagcaaggatgatggtgctgaagaagagaagaatcctggggccaacactgtcaaaaag
ccatctccgtccaaagcacgcaagaagaaactgagcaaaaagggaaggaaaatggcaggc
cggaagcgcgggcgccccaagaaaatgaatgttgtgaatccggagcgcaagaccaagaag
agccaaaccgcactggagcttctccatgctcaagctgtgtcacagacatgctcatcctct
cctcaggatgcatacaggtcacctcatagtccattttaccaactacctcctaaagtgcag
cggcattcatcaaaccagctcttggtgactcctaccccacctgcactgcagaagctgcta
gactctttcaagatccagtacatgcaattcatggcatacatgaagactcctcagtacaaa
gagaaccttcagcaactgctggaacaggaaaaggaaaagaatacacacttgatggggaaa
gcacagcagttgtttactcattgccaagctcagaaagaagaaataaagcggctgttccag
cagaagctagatgagctgggagttaaggcgttgacctacaatgacctaattcaagctcag
aaagagatttctgctcacaaccagcagcttaaagagcagaccaagcagctggagaaagac
aacggggaactcaggaaccagagtctgcagctgctgaaggccaggtgcgaagaattgaag
ctggactggtccacactgtccctggagaacctgctgaaagaaaagcaggcactgaagaac
cagatctccgagaagcaaaagcattgcttggaattgcagattagcatcgtggaacttgag
aaaagccaaaggcagcaagaactcctgcagctgaaatcgtgcatgcctcctgacgaatcg
ctgccggtgcagccacgccacaaaaaccatctgaatcgtgagccagagcctgaccacagc
ctgttccaactggagctggagtgccccaagttcccagtaccccatatcaatggtatgagc
cctgagctgtccatgaacggtcacgccacaccgtatgaggtccatcatgctctcagcagg
ccctcctccaagcagagcacccctcagtatgcaacatcacacctggaccaagacatcgtc
ccttgtaccccaaaccacaactgtaggcagaaaccagacaaggcctcaagcttgtcctta
ccggattacaccagattctccccagccaagatagccctacggaggcacttgaaccaggac
caaacaggcagtgcaaaattgacaacgaatgaaaaccatcacagaacagagcatataaaa
gagaacggcattacatttccgagccctacaataccaaatggcataaagatgagccctcag
gaaccccgtccctcttcaccggcagctgtgccagttgctaatgagaaggctttgcgagag
aggacgcctgcgaataacggggagaccatcaccagccttcccatcagtattcccctcagc
acagtgcagcccaataaactccctgttagtatccccctggccagcgtagttctacctagc
cgtgttgagaaggtgagaaacacacccagccctgtccaccagaaccgtgactccttttca
acgcttgataaacaatgtggtgctagttcccataacggcatgagcagtgtcgctgcaaac
aagtcatttactttggctacctcaggtttttcatacacgacaggctctgggttggccaat
gggactctttcaaacagccctgcccagcttaaccacactgttgaccatgctgctctggag
gatgtgtccagttcgggaagcttgtttagttcagcgggatctcggagttccactccacag
cacccttccttgctgatgatgccatcacggaattcagggcagaactcccctgctcaccag
cactcggcgagccccaggatgaatggggcctctcagggtctgggaggggtactgcagtac
atggactcgcagaaagtgttcactgaagggacacggggggatgcacaggctgacgcagca
ttctctgatcctgaaagtgagggcaagcgaaggatcatcttcaccatctctcctgccaca
ggaaccataaagcattctccttccagtaagcacagctcccttactgcaagcatacggatg
gagtgtgggcaggcctatgtacaggatgggaagaagcgtggccggaggaagcggtcctcc
acgggaacacctaatatgaactccggggtctcaccaaaacgcaaatcgttgccagcagtg
gctggactcttcgctcagccttcggggtctccactgaatatcagttcaatggtcagtaat
attaaccagcctttagaaatcaccgccatttcttcccctgaaaactccctgaagaactcc
cctgtcccgtaccaggacaacgaccagccccctgtgctgaagaaggagaaacccattgct
cagaccaacggtattcattactcaccgctgacttctgacgaggagcagggctcggaggac
gaccataatagcacccgaattgaaagaaaaattgcaacaatatcactggacagcaaatct
ccacaaaagccaatggagagcagcatcagcttagctgggagaaagcaagccagcgaaaac
atgaatagcagcaaatggaagtccaccttttccccaatatctgacatcaacctgaccaaa
accacagacagttctctgcaggcgccatcatccctgagccagaactccctcttcaccttc
aggccctcttctgaggacaccggcgacggtcccaaggttgccgctcactcgaggaagcac
atggccatgtctgctacagggactgagggtctccaccaaaacaccagttccatgaatgga
tttgcttacagtggtgggctgtcggcggacattggtttacatagctttatcgatggtgct
ttgcttccacataaaaccaacgatgcgacaacactggggagctcctcactggggttcctg
gtgcagcgaaacaaagagcctggggtttccgaggcaaacccattcttgagcaaaaggcag
ctagagagcttgggtgccctgaaaggggaagacttaaactggccaggggccaaaggcaaa
gaggctggtgaattgaatgtccgtttggggggctcttcagaaaaggccttggtgctacac
aatggcaaaaccagcaaagggcgggagcgggaggcggagctcaagaacggccacaatctc
ttcatctctgccacggcagccgtcccttctggtggccttctgaatggtaaaagccttgcc
acgtctgtctctgccgctggtagcctggctgggccagctgtctctgctcaggcgcaccac
cccttcttgaactccttgaccgctggctcgcagtttcccctcggccccgtggccttgcaa
gcgaacctcaactctgtgacaaactcctcggtactgcagtccttatttaactcaatgcca
gctgctgctggcctggtccacgtgtcatcggctgcaacacgcctgaccaactcgcatgcc
atggggggcttctctccgggggttacaggtggaacagttggaggtatttttaaccatgtg
gtgccttgtgcctcctcctcttcctcctcctccactccctcttcttccactccctctttc
tcctcctcctcctctgctcctctgcactttggggctgccctcagtaacagctctgtttcc
agctgtgcgatattaaatttaaatcctctgcaggtggcagccagcacctcatccttccat
gtaccccctaatgtggtgacatccagcgaaacccagccagctcagcccctccaccgagca
atggtgcagccctctcttctcacccctccgccccctcctccccctcctaatgtctcatta
ccacctccacctcccctccgcggatcttctaactctgagtcgtctgtccttctgcagagc
ttatcctctttgcaaacagccgaggctttcttgccaccatcctccactgctaatgccgct
ttgtctatcaaactagcttctcttcagcacaaaccctcccgccccacctttaccatccac
cacccacctttgccccgcatggcgctggcgcaggctacacccgcgaacccgcaatccaac
tcggcggctgcgccggctatgtgggtctcccttggcatgcagtctccttacgcttcgcac
ctctctggggttaaaccacgataa
DBGET
integrated database retrieval system
