Eublepharis macularius (Leopard gecko): 129345573
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Entry
129345573 CDS
T09084
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc00230
Purine metabolism
emc01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
129345573 (PDE8A)
Enzymes [BR:
emc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
129345573 (PDE8A)
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Motif
Pfam:
PDEase_I
PDE8
PAS_9
PAS
PAS_3
PAS_4
DUF5894
PAS_8
HTH_Mga
Motif
Other DBs
NCBI-GeneID:
129345573
NCBI-ProteinID:
XP_054858761
UniProt:
A0AA97KNX9
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Position
18:complement(26633121..26753759)
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AA seq
847 aa
AA seq
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MGCAPSIHISDSRVVYHSNKEPEDSNSSQQQQGHPVPGLFIKSSNTSTYKLRTNPSKKDK
RDHSRSMEVETQASRSSIKAVGTDVQFGPMRLHQDQLQVLLVFAKEDNQSNGFCWACEKA
GYRCNVARTPESALECFLDKNHEIIIIDHRHSRYFDAESLCRSIRSTKLAENTVIIGVVR
RHADREESSILPLISAGFTRRYVENANIMACYNELMQLEFGEVRAQFKLRACNSIFTALE
KNQEAIEITSEDHVIQYINPAFETMMGYQKGELIGKEITEVPINEKKADLLETINSCIKI
EKEWQGTYYAKKKSGESIQQNVKIIPVIGQGGKIRHYVSLSSPSNDNNKAERVREHVQAE
SQTDNQSSRHKDRRKGSLDVRSTTSRGSDGSSQRRHSSMARIHSMTIEAPITKVINIINA
AQESSPMPVAEALDRVLEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYI
LSAKQTHQVPGSLISPISLNDIPPRIAQAMENEEHWDFNIFELEAATHKRPLVYLGLKMF
ARFGICEFLNCSELTLRSWLQIIEANYHSSNSYHNSTHAADVLHATAYFLSKERVKQTLD
PIDEVAALLAATVHDVDHPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTRDDK
CNIFKNMERNEYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPLAALDEIGSMSSDGE
SIKNVLTSPENRILIKRMLIKCADISNPCRPVEQCVEWAGRISEEYFAQTDEEKRQGLPV
VMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFADLPNLMQHLDNNFKYWKGLDDRKLR
TLRPPPE
NT seq
2544 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtgctcccagcatccatatctcagacagcagggtggtctaccacagcaacaaa
gagcctgaggactcgaactcatcgcagcagcaacaaggccaccctgtccctgggttattc
attaaatcctccaacacctccacatacaagttaaggacgaacccctccaagaaggacaag
cgtgaccacagccggagcatggaagtagagactcaggccagcagatccagcattaaggca
gtgggaacagatgtgcagtttggccctatgagactccaccaagatcaacttcaggttctt
ttagtgtttgccaaagaagacaaccagagtaatgggttctgctgggcgtgtgagaaagct
ggatatcggtgtaacgttgccaggacacctgaatctgcccttgagtgtttcctggataag
aaccatgaaatcatcattattgatcataggcattcgcgatactttgatgcagaatcacta
tgcaggtccattagatcaacaaaattagctgaaaacactgttattattggtgtcgtgcga
agacatgcggatcgtgaagagtcctcaatattgcccctcatttctgctggcttcacaagg
aggtatgtagaaaatgccaatatcatggcctgttacaacgaactcatgcaactggaattt
ggagaagtgcgggcacaatttaaactaagggcttgtaattcaatatttacggcattagag
aaaaatcaagaagccattgagatcacaagcgaagaccatgtaatacagtacataaatcct
gcgtttgaaacaatgatgggctatcaaaaaggtgaattaataggaaaggaaataacagaa
gtgcctataaatgaaaaaaaagctgatctccttgaaactattaattcttgcatcaagata
gaaaaggaatggcaaggaacgtattatgccaaaaagaaaagcggagagagcatacagcaa
aatgtgaagatcatacctgtcattggacagggaggaaaaattagacactatgtgtcactt
agcagcccaagcaacgacaataataaggccgaaagggtacgcgaacatgttcaagctgag
tcccagacagataaccagtcctccagacacaaagacaggaggaaaggatctctagatgtc
agatcgaccacctcacggggcagtgatggcagttcacagagaaggcactcttctatggcc
agaatacattccatgactatcgaagcgcctattactaaggtgattaatataatcaatgct
gcccaagaaagcagccccatgccggttgctgaagctttagatcgcgtccttgagattctg
aggaccactgagctgtactctccgcagcttgggacaaaagatgaggatcctcatacaagc
gaccttgttggaggcttgatgacggacggtctacgaagattatcagggaatgagtatata
ttatcagcaaaacaaactcatcaggtaccaggcagcttaatctcgcctatctcccttaat
gatataccaccacgaatagcacaagcaatggaaaacgaggaacactgggactttaatatc
tttgaattggaagcagcgacccataaaaggcctttggtttatcttggtctcaaaatgttt
gctcgcttcggaatctgcgagttcctaaactgctctgaattgactctgaggtcttggctg
caaatcatcgaagccaattatcactcatctaattcctaccacaattctacccatgctgcc
gacgtcctccatgccacagcctacttcctttctaaagaaagggtaaaacaaactttggat
cccatcgatgaagtcgcagccctgcttgctgccaccgtgcatgatgtggatcacccgggt
cggacgaattccttcctgtgtaatgcaggaagtgagctggccattttgtacaatgacacg
gcagtgttggagagccatcacgccgctttggccttccagcttaccacgcgggacgataaa
tgcaatatttttaaaaacatggagcggaatgaataccgaaccctccggcaggcgattatc
gacatggtcttagccacggaaatgaccaagcactttgagcatgtcaacaagtttgtcaac
agcataaataagcctttggcagcccttgatgaaatcgggagtatgagcagcgatggcgag
tctatcaaaaacgtcctcacgtcacccgaaaaccgaatcctgattaagcgaatgctcatt
aagtgtgccgatatttccaacccatgtcggcctgtggagcagtgtgttgagtgggctggc
cgcatttctgaggaatattttgcacagacagatgaagagaaaagacaaggtttgcctgtg
gtgatgcctgtttttgacaggaatacttgtagtatccccaaatctcaaatatccttcatt
gattatttcatcaccgacatgttcgatgcttgggacgcatttgcagaccttccaaatttg
atgcaacacctggacaacaacttcaaatactggaagggtctggacgacaggaagctacgg
actcttcggcccccacctgaatag
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