Echinops telfairi (small Madagascar hedgehog): 101650051
Help
Entry
101650051 CDS
T08707
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X2
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf00230
Purine metabolism
etf01100
Metabolic pathways
etf04927
Cortisol synthesis and secretion
etf04934
Cushing syndrome
etf05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101650051 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
101650051 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
101650051 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101650051 (PDE8A)
Enzymes [BR:
etf01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
101650051 (PDE8A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PAS_9
PAS
PAS_3
PAS_4
MiaE
UBA_E1_SCCH
PAS_8
Response_reg
Motif
Other DBs
NCBI-GeneID:
101650051
NCBI-ProteinID:
XP_004708146
LinkDB
All DBs
Position
Unknown
AA seq
759 aa
AA seq
DB search
MRFHQDQLQVLLVFTKEDSQCNGFYRACEKAGFMCSVTKEPQAALACFLDKHHDIIIIDH
RHPRQLDADVLCRTIRASNISENTVIVAVVCRTEKEEPSVLPFVNAGFTRRYFENSSIMA
CYNELIQLEYGEVRSQLKLRACNSIFIALEKSQEAIEITSEDHIIQYANPAFETTMGYQA
GELIGKELAEVPINEKKADLLDTINSYIRIGKEWQGNYCTKKKNGDNIQQHVKIIPVIGQ
GGKIRHYVSIIRVCNGSNKAEKIAECVQPEGLSDMQTSNLIKDKRKDSLDVKSLVSRSGN
EVTHQRRHSSLARIHSMTIDAPITKVINIINAAQESSPMPVTEALDRVLEILRTTELYSP
QFGVKDDDPHANDLVGGLMCDGLRRLSGNEYILSSKNLHQVSSRIINPIALQDIPPRIAK
TMEKEEFWDFNIFELEAATHKRPLIYLGLKIFSRFGICEFLNCSESTLRSWLQIIESNYH
SYNPYHNSTHAADVLHATAYFLSKERIKQTLDPVDEVAALLAATIHDVDHPGRTNSFLCN
AGSKLAILYNDVAVLENHHAALGFQLTIQDDKCNIFKNMEKNDYRMLRQGIVDMVLATEM
TKHFEHVNKFVNSVNKPLESLEENKETNKHAETINTMLRTPENRTLIKRMLIKCADVSNP
CRSLEFCIEWAARISEEYFCQTDEERQKGLPVVMPIFDRQTCSIPKSQISFIDYFITDMF
DSWDAFVDLPDLMQHLDNNFKYWKGLDEMQLRSLRPPPQ
NT seq
2280 nt
NT seq
+upstream
nt +downstream
nt
atgagatttcatcaagatcaacttcaggtacttttagtgtttaccaaagaagatagccag
tgtaatggattctatagggcatgtgaaaaagcagggtttatgtgctcagtaaccaaggag
cctcaggctgcccttgcctgcttcctggacaaacatcatgatatcatcatcatagaccac
agacatcctcgacagctggatgcagacgtgctttgtagaactatcagagcatcaaatatc
tcagaaaacacagttattgttgctgttgtatgcaggacggaaaaagaagaaccatctgta
ttgcccttcgttaatgctggctttacaaggagatatttcgaaaactccagcatcatggcc
tgttacaatgagctcatccagctggagtatggagaagttcgatcccaactgaaactcagg
gcttgtaattcaatattcattgcattagagaaaagtcaagaagcaattgaaattactagt
gaagatcacattatacagtatgcaaatcctgcttttgaaacaacaatgggctatcaggcc
ggtgaattaataggcaaggagttagctgaagtgcctataaatgaaaaaaaggctgacttg
ctcgatactataaattcatacatcaggattggcaaggagtggcaaggaaattactgcacc
aaaaagaaaaatggagataacatacaacaacatgtgaagataatacctgtcattggacag
gggggaaaaattaggcactatgtgtccattatcagagtgtgcaatggcagcaataaggct
gagaaaatagctgaatgtgttcagccagaaggtctttcagatatgcagacaagcaacctt
attaaagacaagagaaaagattcactagatgtcaagtcccttgtcagtcgatcaggaaat
gaagtgactcaccagagacgacactcttccttggcccggatacattccatgacgatcgac
gcacccatcacaaaggtaattaatattatcaatgctgcccaagaaagcagtcccatgcct
gtgacagaagccttagaccgtgtgctggaaattctgcgaaccactgaattatattcacca
cagtttggtgttaaggatgatgatcctcatgccaacgacctcgtcggaggcttaatgtgt
gatggtttgagaagactgtcagggaatgaatatattctttcatcgaagaaccttcaccag
gtctcaagcaggataatcaatcccatcgccctccaagacatcccaccacggatagctaaa
accatggaaaaggaggaattctgggactttaatatttttgaactggaggctgccacccac
aagaggcctttaatttacctaggcctcaaaatattttctcgctttggaatctgtgaattc
ttaaactgctctgaatcaacactccgatcctggttacaaattattgaaagcaattatcat
tcttataacccctaccacaactctacacatgccgctgatgtactgcatgcgacagcctat
ttcctgtccaaagagaggatcaagcaaactttagatccagttgacgaagtcgctgccctg
cttgcagccaccatccatgatgtggatcaccctgggagaaccaactctttcttgtgtaac
gccgggagcaagctggccattttgtataatgacgttgctgtcctggagaatcaccatgca
gccttgggtttccagctgaccattcaagatgataaatgcaatatctttaaaaacatggag
aagaatgactatcggatgctgcgccagggtattgttgacatggtcctagccacagagatg
acaaagcactttgaacatgtcaacaagtttgtcaacagtgtcaacaagcccctggaatca
ctagaagaaaacaaggaaacaaataaacatgcggaaacaataaacactatgcttaggaca
ccagagaaccggactctgatcaaacgaatgctgattaagtgtgctgatgtgtccaacccc
tgtcggtcccttgagttctgcattgagtgggctgcgcgcatctcagaggagtatttctgt
cagactgatgaagagaggcagaaaggcttacctgtggtgatgccaatttttgacagacag
acctgcagcatccccaaatcccagatctccttcattgactacttcatcacagacatgttt
gactcctgggacgcctttgtcgatctgccggacctaatgcagcaccttgacaacaacttc
aagtactggaaaggcctggatgagatgcagctgcgcagcctccggccccctccccagtag
DBGET
integrated database retrieval system
