Echinops telfairi (small Madagascar hedgehog): 101650368
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Entry
101650368 CDS
T08707
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X2
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf00010
Glycolysis / Gluconeogenesis
etf00020
Citrate cycle (TCA cycle)
etf00620
Pyruvate metabolism
etf00785
Lipoic acid metabolism
etf01100
Metabolic pathways
etf01200
Carbon metabolism
etf01210
2-Oxocarboxylic acid metabolism
etf04066
HIF-1 signaling pathway
etf04922
Glucagon signaling pathway
etf05230
Central carbon metabolism in cancer
etf05415
Diabetic cardiomyopathy
Module
etf_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
101650368 (PDHA1)
00020 Citrate cycle (TCA cycle)
101650368 (PDHA1)
00620 Pyruvate metabolism
101650368 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
101650368 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
101650368 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101650368 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101650368 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101650368 (PDHA1)
Enzymes [BR:
etf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
101650368 (PDHA1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
101650368
NCBI-ProteinID:
XP_004709984
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLLGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPETTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLTVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAHCRAGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLTDRMVNNDLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgggtgctgttgggcgccgcccagaagccggct
agcagagtgctggtggcatcacgtaacttcgccaatgatgctacatttgaaattaagaaa
tgcgatcttcaccggctggaagaagggccgcccgagaccaccgtgctcacccgggaggac
gggctccgctactacagaatgatgcagacagtgcgccgcatggagctgaaggccgaccag
ctctacaagcagaagatcatccggggcttctgccacctgtgcgatgggcaggaagcgtgc
tgtgtggggctcgaggctggtattaatcccacggatcatcttatcactgcctaccgggct
catggcttcacctttacccgggggctcaccgtccgagagattctggcagagctaacagga
cggagaggaggttgtgcaaagggcaaaggcggctcaatgcacatgtacgccaagaacttt
tatgggggcaatggcatcgtcggcgcccaggtgcccctgggagctggaatcgctctggcc
tgcaaatacaacggcaaagatgaggtctgcctgactctctacggggatggtgctgctaac
cagggtcagatatttgaagcttataatatggcggctttgtggaaattaccctgtattttc
atctgtgaaaataaccgctatggaatgggaacgtctgtggagagagccgctgccagcaca
gactactacaagcgaggcgacttcatcccggggctccgggtagatgggatggatatcctg
tgcgtccgggaagctacaaagtttgcagctgctcactgcagggctggaaaggggcccata
ctgatggagctgcagacctaccgctaccatggccacagcatgagcgatcctggagtcagt
tatcgtacccgagaagaaattcaggaagtcagaagcaagagtgaccctatcatgcttctc
acggacaggatggtgaacaatgaccttgccagcgttgaagaactgaaggagatcgatgtg
gaagtgagaaaggaaattgaggacgcagcccagtttgctacagcagatccggagccacca
ctggaagaactagggtaccacatctattccagcgacccaccctttgaagttcgtggtgca
aatcagtggatcaagttcaaatccatcagttaa
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