Candidatus Protofrankia datiscae: FsymDg_4048
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Entry
FsymDg_4048 CDS
T01530
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
fsy
Candidatus Protofrankia datiscae
Pathway
fsy00860
Porphyrin metabolism
fsy01100
Metabolic pathways
fsy01110
Biosynthesis of secondary metabolites
fsy01120
Microbial metabolism in diverse environments
fsy01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
fsy00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
FsymDg_4048
Enzymes [BR:
fsy01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
FsymDg_4048
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
FsymDg_4048
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AEH11321
UniProt:
F8AVK7
LinkDB
All DBs
Position
complement(4748987..4750861)
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AA seq
624 aa
AA seq
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MATRRTKKPLTPVALVGAGPRDPGLLTVLAAETLAGADSIIVDPDVAPEIVARLPGEVLR
IGDTDVAKPILDATAATTAVVARARAGERVVRLYSSDPWLTGIGTADAQALAKAKIPFRV
VPGIPTGAAVATYSGISTGLPVTFASTQGVFSASGMRPTVAPAADTPTTGLGSPSFGAGR
LGGRGLSSLGSSGSGLGGPGLGGPGLGGSGLGGSGLGAGLAASPLGSSLGLGGLAGSGSL
DAAGSGSDLDWAALAQAPGTLVVTAVSNEVGKVAAALVEHGRAGDTPVSVTVDGTTTDQR
TVASTLDRIEADAAPVVGNAPSVVISIGAAVTGRNKLSWWESRALFGWTVLVPRTKEQAA
ILSDLLRSHGASPLEVPTIAVEPPRTAAPMERAITGLVSGRYQWVAFTSVNAVRAVQEKV
EERSLDARAFAGVKVAAIGEATADALRAFGIRPDLVPSGQQSSEGLLADWPDYDDVFDPL
DRVLLPRADIATETLVAGLKDRGWNVDDVTAYRTVRAAPPPAPIREALKGGRVDAVVFTS
SSTVRNLVGIAGKPHETTVIAVIGPQTAATAAELGLRVDVQATEASIPSLVQALADFAAE
HREELGKVGPLAARLPKPRRGSRR
NT seq
1875 nt
NT seq
+upstream
nt +downstream
nt
atggccacccgccgcacaaagaagcctctgaccccggtcgccctcgttggagcaggcccg
cgcgaccccggtttgctgacagttctcgccgccgagacactggccggggccgattcgata
atcgtcgatccggacgtcgccccggagattgtcgccaggctgcccggcgaggtgctacgg
atcggcgataccgacgtggcaaaaccaatcctggacgcgaccgcggcgaccaccgccgtc
gtcgcccgggcccgtgccggtgagcgggtcgtacggctgtactcctcggatccgtggctg
accggaatcggcaccgccgacgcgcaggcactggccaaggcgaagattcctttccgggtc
gtgccggggattccgaccggcgcggcagtcgccacctattccgggatctccaccggcctg
ccggtcaccttcgcgagcacccagggggtcttctccgccagcgggatgcggcccaccgtg
gcccccgcggcggacacgcccaccacggggctgggctccccgtccttcggggcgggccgc
ctcggcgggcgcggcctatccagcctcggcagctccggctccggtctcggtggtcctggg
ctgggcggcccagggctcggcgggtccggactgggcggatccgggctcggcgcggggctt
gcggcctcgccgctgggctcctcgctgggactcggcggcctcgccgggagcgggagcctg
gacgccgccggctccggctcggacctcgactgggcggcgctcgcccaggcaccgggcacc
ctcgtggtgacggcggtctccaacgaggtcggcaaggtcgcggcggcgctggtcgagcac
ggccgggccggtgacacccccgtgtcggtgacggtggacggcaccaccaccgaccagcgc
acggtcgcctccaccctggaccggatcgaggccgacgccgcgcccgtcgtcgggaacgcc
ccctccgtggtgatctccatcggggccgcggtcacaggtcgtaacaagctgtcctggtgg
gagtcgcgcgcgctgttcggctggacggtgctggtgccccggacgaaggagcaggcggcg
atcctgtcggatctgctgcgctcgcacggcgcgagcccgctggaggtgcccacgatcgcg
gtggagccgccgcggacggccgctcccatggaacgcgccatcaccggtctggtgtccgga
cgctaccagtgggtggccttcacctcggtcaacgcggtccgggccgtccaggagaaggtc
gaggagcgcagcctggacgcgcgggcgttcgccggcgtcaaggtggccgcgatcggcgag
gcgaccgcggacgccctgcgcgccttcggcatccgccccgacctcgtcccctccggccag
cagtccagcgagggcctgctcgccgactggcccgactacgacgacgtgttcgacccgctc
gaccgggtgctgctgccccgggccgacatcgccaccgagaccctggtggccggcctgaag
gaccgcggctggaacgtcgacgacgtcaccgcgtaccgcacggtacgggccgcgccgccg
ccagccccgatccgggaggcgctcaagggcggccgggtggacgcggtggtgttcacctcc
tcctcgaccgtgcgcaacctggtcgggatcgccggcaagccgcacgagaccacggtgatc
gcggtgatcggcccgcagaccgcggccaccgcggccgagctgggcctgcgggtcgacgtc
caggcgaccgaggcgtcgatcccgtcgctggtgcaggcgctggccgacttcgccgccgag
caccgggaggaactgggcaaggtcggcccgctcgcggcccggctgcccaagcctcggcgc
ggttctcggcggtga
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