Francisella tularensis subsp. novicida U112: AW25_507
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Entry
AW25_507 CDS
T03874
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
ftx
Francisella tularensis subsp. novicida U112
Pathway
ftx00010
Glycolysis / Gluconeogenesis
ftx00020
Citrate cycle (TCA cycle)
ftx00620
Pyruvate metabolism
ftx00785
Lipoic acid metabolism
ftx01100
Metabolic pathways
ftx01110
Biosynthesis of secondary metabolites
ftx01120
Microbial metabolism in diverse environments
ftx01200
Carbon metabolism
ftx01210
2-Oxocarboxylic acid metabolism
Module
ftx_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ftx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
AW25_507 (aceE)
00020 Citrate cycle (TCA cycle)
AW25_507 (aceE)
00620 Pyruvate metabolism
AW25_507 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AW25_507 (aceE)
Enzymes [BR:
ftx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
AW25_507 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AJI61489
UniProt:
A0Q7Z6
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Position
539371..542052
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AA seq
893 aa
AA seq
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MSDFTKDIDVLETQEWLEAFEDVVKREGADRAKFLFEQLLAKGSELGIKSAYSTAKVKNY
VNSIDVSEQPSYPGDIELEQKIEAINRWNSTVIVAAANKKDGSIGGHIGTGAGAMTLYEV
GFNHFWKAPNDEHAGDLIFYQGHLSPIVYARSFLEGRITAEQLENFRKQAFNGQNAVSSY
PHPYLQPTYWQFPTVSMGLGPLQAIYQARFMKYLEARGLAKTSDRKVWAFCGDGEMDEPE
SIGSITRAGREGLDNLIFVVNCNLQRLDGLVNGNGNIVEELADVFAGAGWNVIKVLWSSD
WDKLLQDPRGGKKLAQRLSELNDGQFHTIKAHGGAECRRVVFSGDEDLEALAKDMTDDDI
QALRRGGHDPLKIYAAYKKAVENPNGRPTLILPMTVKGYGLGEWGESKNIAHNVKKLDTD
ALEHIKNRFNVPASKEDIENYRLIKLDENSPEMKYLHSKRKDLGGYIPKRLENKQALEIP
SYKDFAKSLLDDSGDREFSTTTAFVRILSHLAKDKNLGKHIVPITVDESRTFGMEGLFRQ
LGIYNPHGQQYVPEDKQQVMFYKESVDGQILQEGINEQGGFCSWIAAATSYSVHKVPMIP
FMIYYSMFGFQRFGDLAWAAGDSMAKGFVIGGTSGRTTLNGEGLQHEDGHSHIQAGLIPN
CISYDPTYAYELAVILGEGMKRMYVDGDHVYYYITVMNENYSHRAMPEGCEEGIIKGLYK
LDEEKKPAAKHVQLLGSGSILREVEAAAKMLKEEYGITSNVWSMTSANELYREAKDVART
NMLHPTAEKKESYIEKCFKNEQGPVIASTDYIKLYTDQLREFIPHTFVNLGTDGFGRSDT
RAALRSFFEVDRYHVVVASLYALYLDGKVEASEVKAAIEKYNIDPERMAPFYS
NT seq
2682 nt
NT seq
+upstream
nt +downstream
nt
atgtcggatttcactaaagatattgatgttttagaaacccaagaatggcttgaggctttt
gaagatgtcgtaaaaagagaaggtgctgatagagccaagtttttatttgaacaattactt
gctaaaggttccgagcttggtataaaaagtgcttactcaactgctaaagttaagaactat
gtcaactctatagatgtctctgaacaaccaagttatccaggagatatagagcttgaacaa
aagattgaagctatcaatagatggaactctacagttatagtagctgcagctaataagaaa
gatggctctataggtgggcatattggtactggtgccggcgctatgacgctttatgaagta
ggcttcaaccatttttggaaagcaccaaatgatgaacatgctggtgatttgatattctat
caaggacatctttctcctattgtttatgcgcgttcattcctagaaggtagaataactgca
gaacagttagaaaactttagaaagcaagcatttaatgggcaaaatgcggtatcttcatat
cctcatccttatctacaaccgacttattggcagttcccaactgtttctatggggttagga
ccacttcaagctatttatcaagctagatttatgaagtatctagaggctagaggtttagca
aaaacatctgatcgcaaagtttgggcattctgtggtgatggcgagatggatgagccagaa
tcaattggttctatcactagagcaggtcgtgaagggctagataaccttatatttgtagtt
aattgtaatctacaaaggctagatggtctggtaaatggtaatggtaatattgttgaagaa
ttagcagatgtatttgctggtgctggttggaatgttatcaaggtgttgtggagtagtgac
tgggataaattattacaagacccaagaggtggtaaaaaacttgctcaaaggttgagtgaa
ttaaatgatggacaattccatacaattaaagctcatggtggtgctgagtgtcgtagagtt
gtctttagtggtgatgaagatttagaagcgctagctaaggatatgacagatgatgatatt
caagcattacgtcgtggtggacatgatccattgaaaatttatgcagcatataagaaggca
gtagagaatccaaatggtcgtccaacactaattcttcctatgactgttaagggctatggt
ttaggtgagtggggtgagtcaaaaaatattgcccacaatgtcaaaaaacttgatactgat
gcacttgagcacatcaaaaatagattcaatgtcccggcttcaaaagaggatatcgaaaac
tatagactcatcaagctagatgaaaattcgcctgagatgaaatatctacactctaagaga
aaagacctaggtggttatattcctaagagattagagaataagcaagcattagagattcca
agctataaagattttgctaagagcttattggatgatagtggtgacagagagttttcaact
actaccgcatttgtaagaatattatcccacttggcaaaagataagaatctagggaagcat
attgtaccaatcacggtagacgagtcacgtacttttggtatggagggcttgtttaggcaa
ttaggtatctataacccacatggtcagcaatatgtaccagaagataaacagcaagtaatg
ttctataaagaatctgtagatggtcagattttacaagaaggtattaatgagcaaggaggt
ttttgttcttggattgccgcagctacttcatatagcgtacacaaggttccaatgattcct
ttcatgatttactactcaatgtttggtttccaaagatttggtgatcttgcttgggcagct
ggcgattcgatggcaaaaggttttgtaattggtgggacttcaggacgtacaactctaaat
ggcgaaggtttgcagcatgaagatggtcatagccatatccaagctggtcttatacctaat
tgtatctcttatgatcctacatatgcatatgaattagctgtaatccttggcgaaggtatg
aagagaatgtatgttgatggtgatcatgtatattactatattacagtaatgaatgagaac
tactctcatagagcgatgccagagggctgtgaagaaggtatcatcaagggcttatataaa
ttagacgaagagaaaaaaccagcggctaaacatgtacagttattaggttctggttctatt
ctaagagaagttgaagctgcagctaagatgctaaaagaagagtatggaattacttctaat
gtttggagtatgacttcagcaaatgagctttatagagaagctaaagatgtagctagaact
aatatgcttcatccaacagcagagaaaaaagaaagctatatcgagaagtgctttaaaaat
gagcaaggtcctgtaatcgcttctactgactatattaagctttatactgatcagttaaga
gagtttataccgcatacttttgtgaacttaggtacagacggctttggtagatcggatact
cgagcagcgctaagaagtttcttcgaggttgatagatatcatgtcgttgttgcttcatta
tatgctctatatttagatggcaaagttgaggctagcgaagttaaagctgcgattgagaag
tacaatatagatccagagcgtatggcacctttttatagctaa
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