Francisella tularensis subsp. novicida DPG 3A-IS: CH70_440
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Entry
CH70_440 CDS
T03875
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
fty
Francisella tularensis subsp. novicida DPG 3A-IS
Pathway
fty00010
Glycolysis / Gluconeogenesis
fty00020
Citrate cycle (TCA cycle)
fty00620
Pyruvate metabolism
fty00785
Lipoic acid metabolism
fty01100
Metabolic pathways
fty01110
Biosynthesis of secondary metabolites
fty01120
Microbial metabolism in diverse environments
fty01200
Carbon metabolism
fty01210
2-Oxocarboxylic acid metabolism
Module
fty_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
fty00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CH70_440 (aceE)
00020 Citrate cycle (TCA cycle)
CH70_440 (aceE)
00620 Pyruvate metabolism
CH70_440 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CH70_440 (aceE)
Enzymes [BR:
fty01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CH70_440 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AJJ47017
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Position
455976..458657
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AA seq
893 aa
AA seq
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MSDFTKDIDVLETQEWLEAFEDVVKREGADRAKFLFEQLLAKGSELGIKSAYSTAKVKNY
VNSIDVSEQPSYPGDIELEQKIEAINRWNSTVIVAAANKKDGSIGGHIGTGAGAMTLYEV
GFNHFWKAPNDEHAGDLIFYQGHLSPIVYARSFLEGRITAEQLENFRKQAFNGQNAVSSY
PHPYLQPTYWQFPTVSMGLGPLQAIYQARFMKYLEARGLAKTSDRKVWAFCGDGEMDEPE
SIGSITRAGREGLDNLIFVVNCNLQRLDGLVNGNGNIVEELADVFAGAGWNVIKVLWSSD
WDKLLQDPRGGKKLAQRLSELNDGQFHTIKAHGGAECRRVVFSGDEDLEALAKDMTDDDI
QALRRGGHDPLKIYAAYKKAVENPNGRPTLILPMTVKGYGLGEWGESKNIAHNVKKLDTD
ALEHIKNRFNVPASKEDVENYRLIKLDENSPEMKYLHSKRKDLGGYIPKRLENKQALDIP
SYKDFAKSLLDDSGDREFSTTTAFVRILSHLAKDKNLGKHIVPITVDESRTFGMEGLFRQ
LGIYNPHGQQYVPEDKQQVMFYKESVDGQILQEGINEQGGFCSWIAAATSYSVHKVPMIP
FMIYYSMFGFQRFGDLAWAAGDSMAKGFVIGGTSGRTTLNGEGLQHEDGHSHIQAGLIPN
CISYDPTYAYELAVILGEGMKRMYVDGDHVYYYITVMNENYSHRAMPEGCEEGIIKGLYK
LDEEKKPAAKHVQLLGSGSILREVEAAAKMLKEEYGITSNVWSMTSANELYREAKDVART
NMLHPTAEKKESYIEKCFKNEQGPVIASTDYIKLYTDQLREFIPHTFVNLGTDGFGRSDT
RAALRSFFEVDRYHVVVASLYALYLDGKVEASEVKAAIEKYNIDPERMAPFYS
NT seq
2682 nt
NT seq
+upstream
nt +downstream
nt
atgtcggatttcactaaagatattgatgttttagaaacccaagaatggcttgaggctttt
gaagatgtcgtaaaaagagaaggtgctgatagagccaagtttttatttgaacaattactt
gctaaaggttccgagcttggtataaaaagtgcttactcaactgctaaagttaagaactat
gtcaactctatagatgtctctgaacaaccaagttatccaggagatatagagcttgaacaa
aagattgaagctatcaatagatggaactctacagttatagtagctgcagctaataagaaa
gatggctctataggtgggcatattggtactggtgccggcgctatgacgctttatgaagta
ggcttcaaccatttttggaaagcaccaaatgatgaacatgctggtgatttgatattctat
caaggacatctttctcctattgtttatgcgcgttcattcctagaaggtagaataactgca
gaacagttagaaaactttagaaagcaagcatttaatgggcaaaatgcggtatcttcatat
cctcatccttatctacaacctacttattggcagttcccaactgtttctatggggttagga
ccacttcaagctatttatcaagctagatttatgaagtatctagaggctagaggtttagca
aaaacatctgatcgcaaagtttgggcattctgtggtgatggcgagatggatgagccagaa
tcaattggttctatcactagagcaggtcgtgaagggctagataaccttatatttgtagtt
aattgtaatctacaaaggctagatggtctggtaaatggtaatggtaatattgttgaagaa
ttagcagatgtatttgctggagctggttggaatgttatcaaggtgttgtggagtagtgac
tgggataaattattacaagacccaagaggtggtaaaaaacttgctcaaaggttaagtgag
ttaaatgatggacaattccatacaattaaagctcatggtggtgctgagtgtcgtagagtt
gtctttagtggtgatgaagatttagaggcgttagctaaggatatgacagatgatgatatt
caagcattacgtcgtggtggacatgatccattgaaaatttatgcagcatataagaaggct
gtagagaatccaaatggtcgtccaacactaattcttcctatgactgttaagggctatggt
ttaggtgagtggggtgagtcaaaaaatattgcacacaatgtcaaaaaacttgatactgat
gcacttgagcacatcaaaaatagattcaatgtcccggcttcaaaagaggatgttgagaac
tatagacttatcaagctagatgaaaactcgccagagatgaaatatctacactctaagaga
aaagatctaggtggctatattcctaagagattagagaataagcaagcattagatattcca
agctataaagattttgctaagagcttattggatgatagtggtgacagagagttttcaact
actaccgcatttgtaagaatattatcccacttggcaaaagataagaatctagggaagcat
attgtaccaatcacggtagacgagtcacgtacttttggtatggagggcttgtttaggcaa
ttaggtatctataacccacatggtcagcaatatgtgccagaagataaacagcaagtaatg
ttctataaagaatctgtagatggtcagattttacaagaaggtattaatgagcaaggaggt
ttttgttcttggattgccgcagctacttcatatagcgtacacaaggttccaatgattcct
ttcatgatttactactcaatgtttggtttccaaagatttggtgatcttgcttgggcagct
ggcgattcgatggcaaaaggttttgtaattggtgggacttcaggacgtacaactctaaat
ggcgaaggtttgcagcatgaagatggtcatagccatatccaagctggtcttatacctaat
tgtatctcttatgatcctacatatgcttatgaattagctgtaatccttggcgaaggtatg
aagagaatgtatgttgatggtgatcatgtatattactatatcactgtaatgaatgagaat
tactctcatagagctatgccagagggttgtgaagaaggtattatcaagggtttatataag
ttagatgaagagaaaaagccagcggctaaacatgtacagttattaggttctggttctatt
ctaagagaagttgaagctgcagctaagatgctaaaagaagagtatggaattacttctaat
gtttggagtatgacttcagcaaatgagctttatagagaagctaaagatgtagctagaact
aatatgcttcatccaacagcagagaaaaaagaaagctatatcgagaagtgctttaaaaat
gagcaaggtcctgtaatcgcttctactgactatattaagctttatactgatcagttaaga
gagtttataccgcatacttttgtgaacttaggtacagacggctttggtagatcggatact
cgagcagcgctaagaagtttctttgaggttgatagatatcatgtcgttgttgcttcatta
tatgctctatatttagatggcaaagttgaggctagcgaagttaaagctgcgattgagaag
tacaatatagatccagagcgtatggcacctttttatagctaa
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