Gorilla gorilla gorilla (western lowland gorilla): 101144696
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Entry
101144696 CDS
T02442
Symbol
INSR
Name
(RefSeq) insulin receptor isoform X1
KO
K04527
insulin receptor [EC:
2.7.10.1
]
Organism
ggo
Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo04010
MAPK signaling pathway
ggo04014
Ras signaling pathway
ggo04015
Rap1 signaling pathway
ggo04022
cGMP-PKG signaling pathway
ggo04066
HIF-1 signaling pathway
ggo04068
FoxO signaling pathway
ggo04072
Phospholipase D signaling pathway
ggo04150
mTOR signaling pathway
ggo04151
PI3K-Akt signaling pathway
ggo04152
AMPK signaling pathway
ggo04211
Longevity regulating pathway
ggo04213
Longevity regulating pathway - multiple species
ggo04520
Adherens junction
ggo04910
Insulin signaling pathway
ggo04913
Ovarian steroidogenesis
ggo04923
Regulation of lipolysis in adipocytes
ggo04930
Type II diabetes mellitus
ggo04931
Insulin resistance
ggo04932
Non-alcoholic fatty liver disease
ggo04960
Aldosterone-regulated sodium reabsorption
ggo05010
Alzheimer disease
ggo05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ggo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101144696 (INSR)
04014 Ras signaling pathway
101144696 (INSR)
04015 Rap1 signaling pathway
101144696 (INSR)
04066 HIF-1 signaling pathway
101144696 (INSR)
04068 FoxO signaling pathway
101144696 (INSR)
04072 Phospholipase D signaling pathway
101144696 (INSR)
04022 cGMP-PKG signaling pathway
101144696 (INSR)
04151 PI3K-Akt signaling pathway
101144696 (INSR)
04152 AMPK signaling pathway
101144696 (INSR)
04150 mTOR signaling pathway
101144696 (INSR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
101144696 (INSR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
101144696 (INSR)
04923 Regulation of lipolysis in adipocytes
101144696 (INSR)
04913 Ovarian steroidogenesis
101144696 (INSR)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
101144696 (INSR)
09149 Aging
04211 Longevity regulating pathway
101144696 (INSR)
04213 Longevity regulating pathway - multiple species
101144696 (INSR)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101144696 (INSR)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101144696 (INSR)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
101144696 (INSR)
04932 Non-alcoholic fatty liver disease
101144696 (INSR)
04931 Insulin resistance
101144696 (INSR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ggo01001
]
101144696 (INSR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ggo04090
]
101144696 (INSR)
Enzymes [BR:
ggo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101144696 (INSR)
Protein kinases [BR:
ggo01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
101144696 (INSR)
CD molecules [BR:
ggo04090
]
Proteins
101144696 (INSR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Recep_L_domain
Insulin_TMD
fn3
Kinase-like
DUF4476
B2
Motif
Other DBs
NCBI-GeneID:
101144696
NCBI-ProteinID:
XP_030860059
Ensembl:
ENSGGOG00000013703
LinkDB
All DBs
Position
19:complement(3966510..4039159)
Genome browser
AA seq
1062 aa
AA seq
DB search
MNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAE
LEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWD
WSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELL
KFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVD
IDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDAT
NPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKL
PSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVV
FVPRKTSSGTGAEDPRPSRKRRSLGDVGNVTVAVPTVAAFPNTSSTSVPTSPEEHRPFEK
VVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHE
IFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGN
YSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLR
KRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGSFGMVYEG
NARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTL
VVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDL
AARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMW
SFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMR
PTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMENVPLDRSSHCQREEA
GGRDGGSSLGFKRSYEEHIPYTHMNGGKKNGRILTLPRSNPS
NT seq
3189 nt
NT seq
+upstream
nt +downstream
nt
atgaattccagcaacttgctgtgcaccccatgcctgggtccctgtcccaaggtgtgccac
ctcctagaaggcgaaaagaccatcgactcggtgacgtctgcccaggagctccgaggatgc
accgtcatcaacgggagtctgatcatcaacattcgaggaggcaacaatctggcagctgag
ctagaagccaacctcggcctcattgaagaaatttcagggtatctaaaaatccgccgatcc
tacgctctggtgtcactttccttcttccggaagttacgtctgattcgaggagagaccttg
gaaatcgggaactactccttctatgccttggacaaccagaacctaaggcagctctgggat
tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataaccccaaa
ctctgcttgtcagaaatccacaagatggaagaagtttcaggaaccaaggggcgccaggag
agaaacgacattgccctgaagaccaatggcgaccaggcatcctgtgaaaatgagttactt
aaattttcttacattcggacatcttttgacaagatcttgctgagatgggagccgtactgg
cccccagacttccgagacctcttggggttcatgctgttctacaaagaggccccttatcag
aatgtgacggagttcgacgggcaggatgcatgtggttccaacagttggacggtggtagac
attgacccacccctgagatccaatgaccccaaatcacagaaccacccagggtggctgatg
cggggtctcaagccctggacccagtatgccatcttcgtgaagaccctggtcaccttttcg
gatgaacgccggacctatggggccaagagtgacatcatttatgtccagacagatgccacc
aacccctccgtgcccctggatccaatctcagtgtctaactcatcatcccagattattttg
aagtggaaacccccctccgaccccaatggcaacatcacccactacctggttttctgggag
aggcaggcggaagacagtgagctgttcgagctggattattgcctcaaagggctgaagctg
ccctcgaggacctggtctccaccattcgagtctgaagattctcagaagcacaaccagagt
gagtatgaggattcggccggcgaatgctgctcctgtccaaagacagactctcagatcctg
aaggagctggaggagtcctcgtttaggaagacgtttgaggattacctgcacaacgtggtt
ttcgtccccagaaaaacctcttcaggcactggtgccgaggaccctaggccatctcggaaa
cgcaggtcccttggcgatgttgggaatgtgacggtggccgtgcccacggtggcagctttc
cccaacacttcctcaaccagcgtgcccacgagtccagaggagcacaggccttttgagaag
gtggtgaacaaggagtcgctggtcatctccggcttgcgacacttcacgggctatcgcatc
gagctgcaggcttgcaaccaggacacccctgaggaacggtgcagtgtggcagcctacgtc
agtgccaggaccatgcctgaagccaaggctgatgacattgtcggccctgtgacgcatgaa
atctttgagaacaacgtcgtccacttgatgtggcaggagccgaaggagcccaatggtctg
atcgtgctgtatgaagtgagttatcggcgatatggtgatgaggagctgcatctctgcgtc
tcccgcaagcacttcgctctggaacggggctgcaggctgcgtggactgtcaccggggaac
tacagcgtgcgagtccgggccacctcccttgcgggcaacggctcttggacggaacccacc
tatttctacgtgacagactatttagatgtcccgtcaaatattgcaaaaattatcatcggc
cccctcatctttgtctttctcttcagtgttgtgattggaagtatttatctattcctgaga
aagaggcagccagatgggccgctgggaccgctttatgcttcttcaaaccctgagtatctc
agtgccagtgatgtgtttccatgctctgtgtacgtgccggacgagtgggaggtgcctcga
gagaagatcaccctccttcgagagctggggcagggctccttcggcatggtgtatgagggc
aatgccagggacatcatcaagggtgaggcagagacccgcgtggcggtgaagacggtcaac
gagtcagccagtctccgagagcggattgagttcctcaatgaggcctcggtcatgaagggc
ttcacctgccatcacgtggtgcgcctcctgggagtggtgtccaagggccagcccacgctg
gtggtgatggagctgatggctcacggagacctgaagagctacctccgttctctgcggcca
gaggctgagaataatcccggccgccctccccctacccttcaagagatgattcagatggcg
gcagagattgctgacgggatggcctacctgaacgccaagaagtttgtgcatcgggacctg
gcagcgagaaactgcatggtcgcccatgattttactgtcaaaattggagactttggaatg
accagagacatctatgaaacggattactaccggaaagggggcaagggtctgctccctgta
cggtggatggcgccggagtccctgaaggatggggtcttcaccacttcttctgacatgtgg
tcctttggcgtggtcctttgggaaatcaccagcttggcagaacagccttaccaaggcctg
tctaatgaacaggtgttgaaatttgtcatggatggagggtatctggatcaacccgacaac
tgtccagagagagtcactgacctcatgcgcatgtgctggcaattcaaccccaagatgagg
ccaaccttcctggagattgtcaacctgctcaaggacgacctgcaccccagctttccagag
gtgtcgttcttccacagcgaggagaacaaggctcccgagagtgaggagctggagatggag
tttgaggacatggagaatgtgcccctggaccgctcctcgcactgtcagagggaggaggcg
gggggccgggatggagggtcctcgctaggtttcaagcggagctacgaggaacacatccct
tacacacacatgaacggaggcaagaaaaacgggcggattctgaccttgcctcggtccaat
ccttcctaa
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