Geotrypetes seraphini (Gaboon caecilian): 117364629
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Entry
117364629 CDS
T09159
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
gsh
Geotrypetes seraphini (Gaboon caecilian)
Pathway
gsh00310
Lysine degradation
gsh01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
gsh00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
117364629 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
gsh03036
]
117364629 (DOT1L)
Enzymes [BR:
gsh01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
117364629 (DOT1L)
Chromosome and associated proteins [BR:
gsh03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
117364629 (DOT1L)
HMT complexes
Dot1-containing complex
117364629 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
117364629
NCBI-ProteinID:
XP_033809915
UniProt:
A0A6P8RW19
LinkDB
All DBs
Position
8:complement(94323525..94927917)
Genome browser
AA seq
1741 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKCFESMQRLCEKYNRAIDSIHQLWKGTTQPMKLNKRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATSCK
HHYGIEKADIPAKYAETMDKEFRKWMKWYGKKHGEYTLERGDFLSEEWKERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRDNKSNTTTPTKVQ
ENKDSGAEEDKTGTAVVKKPSPVKPRKKKLSKKGRKMAGRKRGRPKKMSIANSERKAKKN
QTALDILHAQTVSQTTSSPQDTYKSPHSPYYQLPPKVQRHPSNQLLVAPTPPALQKLLDS
FKIQYMQFMAYMKTPQYKANLQQLLEQEKEKNTQLLGTAQQLFSHCQAQKEEIKRLFQQK
LNELGVKALTYDDLIQAQKEISAHNQQLKEQTRQLAKDNGELRKQSLQLLKARCEELKLD
WHTLSLENLLKEKQVLKNQISEKQKHCLELQISIVELEKTQRQQELMQLKSCMPSEDALP
VNLRNKSLLNHEPDTDHRRFQLELECTKFPVSQVNGMSPELSMNGHATSYEIHSALSRSS
SKQNTPQYLTSHMDQEIVPCTPNHNSRQKDKSSSLSLPDYTRFSPAKIALRRHLNQDHAI
SGKATVNEVHHRVENIKENGFTHPSPSNSSGIQLSPQESHPSSPAALQIAGERSDEKVLR
ERTSPGNPETITSLPISIPLSTVQPNKLPVSIPLASVVLPSRVEKVRSTPSPVHQSRESS
VLDKPFGATSNNSISNAAGNKPLSLATSGFSYFSGSMAVNGAVFNAQAQLNNHGVDQAAF
EDSSSSGSLFNSSGSRSSTPLHPALLLMQSRGSGQNSPAHQHSASPRLNGSSQSIGGVLQ
YSDPPKIFAEGAKGDLQHDSGFSDPESESKRRIILTLSGSARQSPSSKYSPLTATIRMDC
GPAFVQDGKKRGRRKRLSNGTSNLGVSPKRKSLPTVASLSAQSSGSPLNINSMVSNINQP
LEITAISSPENSLKNSPAPYQDNDQPPVLKKEKPIGQSNGIHFLPVTSDEEQESEDEHNS
TRIERKIATISLESRDSPQKCDSEKAGESLSGRKQAQTNENINSSKWKSTFSPISDINLI
RTPDSPSQALSPLSHNAMFVHRPLPEDGLCAEAKTVTHTRKNPAIFSVMDGSSPNTTLTN
GYTYSGALSADSSLHNFNNGASLSHKISDVAILNSGLSFQSQRNKDASISEANLFLSKRQ
LEGLNSIKGDDLTRLLIKSKEVAELGLRMEKGSLQHNGMICKGRDREVEFKNGHNRFIST
ASGGLLNGKSLPTSVSSLGSLASSVEAHHHFLNTLSTGSQFPLSPVSLQGNLNSVASSSV
LQSLFSSMPAAASLVHVSSAATRLTNSQAVGNFTTPGVTSGTVGGIFNHAMSSAASHQFG
TSFVNGASPSSMMLNQFQAAAAAAAAAKTSPPFQPASSSSVPSSESKATHHRSPASVQCV
PRTPPPLNISLPLPPPLLASNSAEPARLPSLSSISTNDAFLPPCSTVPVQSANSLSIKLA
SMQQKASLPSFTVHHQPLPCLAVAQSTPLIPQSNTSSSSAMWVTLGMQSPYASHLSGVKP
R
NT seq
5226 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagaagctggaactgaggctgaagtcccccgtcggagccgaaccagctgtctac
ccttggcctctacctgtttacgacaaacaccatgatgctgctcatgaaattattgaaaca
attcgatgggtctgtgaagaaatcccagatctcaaacttgcaatggaaaactatgtgcta
attgattatgatacaaaatgttttgagagtatgcagaggctatgtgaaaaatataatcga
gccattgatagcattcatcagttgtggaaaggaaccacgcagcccatgaaactaaacaaa
cgaccttccaatggactccttcggcatatcctgcagcaggtatataaccactcggtgaca
gacccagagaaactcaacaactacgagcccttttcccccgaggtatatggagaaacttcc
tttgacttggtggcccagatgattgatgaaatcaaaatgactgaggatgacttgtttgtt
gacttgggcagtggagtgggtcaggttgtgcttcaggttgctgcagccacgagctgtaaa
catcactatggcattgagaaagcggatattccagcaaagtatgcagagaccatggataaa
gagttcagaaaatggatgaaatggtatgggaagaagcatggagaatatacactggaaaga
ggggacttcctctcagaagagtggaaagagagaatagcaaatacaagtgttatttttgtg
aataattttgcctttggtcctgaggtggatcaccaactgaaggagcgatttgccaacatg
aaggaaggtggtagaatcgtgtcctccaagccttttgcacctctgaattttagaataaat
agtcgaaacttgagcgatattggcactatcatgagagttgtggagctatcaccacttaag
ggatcagtctcatggaccggaaaaccagtttcttactacctgcatactattgatcgaaca
atacttgaaaattatttttctagtctcaaaaatccaaaactcagggaagaacaagaagca
gctaggcgtcgacagcagagagacaacaagagcaacacaactactccaacaaaggttcag
gaaaacaaggattctggtgctgaagaagataaaactgggacagcagtggttaaaaagcca
tctcctgtgaagccacgcaagaagaagctgagtaagaaaggaagaaagatggctggcagg
aagcgtggtcgtcccaagaagatgagcatagcaaactcagaacgcaaggccaagaagaac
caaactgcactggatatcctgcatgctcaaactgtgtcccagacgacatcttcccctcag
gatacctacaagtcacctcatagtccatactaccagctacctcctaaagtacaacgacat
ccatccaatcagctgttagtggcacccaccccacctgcactacagaagctgctagactct
ttcaagatccagtatatgcagttcatggcttacatgaaaactcctcagtataaagcaaac
ttgcagcagttactggaacaggaaaaggagaaaaacactcagttgttgggtacagctcag
cagctcttcagccactgccaggcacagaaagaggagatcaagcggctgtttcagcagaaa
ctcaatgagctgggtgtgaaagctctgacatatgatgacctgatccaggcacagaaggag
atctctgctcacaaccagcagctgaaggagcagacaaggcaactggcaaaagacaatggt
gaactcagaaagcagagcttgcagctgcttaaggctcggtgcgaggaactgaagctggac
tggcatacactttcactggagaacttgctgaaagaaaagcaggttctgaagaatcagatt
tccgagaagcaaaaacactgcttggaactacagatcagcattgtggagctggaaaagacc
caaagacagcaggagcttatgcagctgaagtcatgcatgccatcagaagatgcactgcca
gtgaacctacgcaataaaagccttttaaaccatgaacccgacacagatcaccgcaggttc
cagctagagctggaatgcaccaagttccctgtgtcccaagtaaatggcatgagcccagag
ctctctatgaatggtcatgccacctcatatgaaatccatagtgctctgagcaggtcctca
tccaagcagaacacccctcagtacttgacatctcatatggaccaagaaattgttccctgc
accccaaaccacaacagcagacagaaagataagtcctccagtttgtccttgccagattac
acccggttttctccagctaagattgccctacgaaggcacttgaatcaggatcatgctatc
agtggaaaagcaacagtgaatgaagtacatcatagagtggaaaatataaaagagaatggc
ttcactcatccaagccctagcaattccagcggcatccagttgagccctcaggaatctcac
ccttcttccccagcggccttacagattgcaggagagaggagtgatgagaaggtgttgcgc
gaaagaacctctccaggtaatcctgaaacaatcaccagcctgcctatcagtattcccctc
agcaccgtgcagcctaacaaactccctgttagtatcccactggccagcgtggttctgcct
agccgtgttgagaaggtgagaagcacacctagtccagttcatcagagcagagagtcatct
gtccttgacaaaccatttggtgctacttccaataacagtataagcaatgctgcaggaaac
aagccactgtccttggctacctcaggtttttcttatttttctggctcgatggcagtgaat
ggagcagttttcaatgcccaagctcagctcaataaccatggtgttgatcaggcagctttt
gaagactcatcaagttcgggttccttgtttaactcatcaggatctcgaagctctactcca
ttacatcctgctttgcttttaatgcaatctcggggctctgggcagaattcccctgcccac
cagcactcagcaagtccaaggttgaatggttcttctcagagtataggaggagtattacag
tattctgatcctccaaaaatatttgctgaaggagcaaaaggggatttacaacatgacagt
gggttttcagatccagagagtgagtcaaagaggagaataatcttaaccctctcaggctca
gcaaggcagtctccctcaagtaagtatagccccctaacagcaaccatcaggatggactgt
gggccagcatttgtgcaggatggcaagaaacgaggcagaaggaagcgattgtctaatggg
acttcaaatctgggagtgtcacccaaacgcaaatctttgcctactgtagcaagtctgtct
gctcagtcctctggttccccactcaacattaactctatggtcagtaacattaaccagcct
ttagagataacagccatttcttcacctgagaactcgctgaaaaattctccagccccttat
caagacaatgaccaacccccagttttgaaaaaagagaaaccaattggtcagtctaatggc
atccattttctgccagtgacctccgatgaagagcaagaatctgaagatgagcacaatagc
actaggattgaaagaaaaattgcaacaatctcactggaaagcagagattctcctcagaag
tgcgacagtgagaaagcaggagaaagtttatctgggcggaagcaagcacaaaccaatgag
aacataaatagcagtaaatggaagtcaactttttccccaatatctgacataaacttgatc
agaactccggacagcccatcacaggctctctcacctttgagccacaatgctatgtttgtt
cataggccattgcctgaggatggtctctgtgctgaggccaagactgtgactcacacaagg
aagaaccctgcaatcttctcagtaatggatggatctagccccaacacaaccctaacaaat
ggatatacttacagtggtgcactgtcagctgatagcagtttacacaatttcaacaatggt
gcttctctctcacacaaaatatcagatgtggcgatcttaaactctgggctgagctttcaa
tcccagcgtaacaaagatgccagcatctcggaggccaatctctttttgagtaagagacag
ctggagggcttaaacagcataaaaggggatgacctcactaggttattgatcaagagcaaa
gaagtagcagaattaggactccggatggaaaagggctccttgcagcacaatggcatgatt
tgcaaagggcgggaccgagaggtggagtttaaaaatggtcataaccgttttatctccact
gcttctggaggtcttctcaatggcaaaagcctgcccacctcagtatcatccctagggagc
ctggcctcatctgttgaggctcaccatcacttcttaaacacactcagcactggatcacag
ttccctcttagcccagtttccctgcagggaaacctcaactctgtggccagctcatcggtg
ttacagtcactgttcagttctatgccagctgcggccagcctggtccatgtatcatctgcc
gcaaccagattgaccaattcacaggctgtgggaaacttcaccactcctggcgtgacaagt
ggaactgttggaggtatttttaaccatgcgatgtcttctgctgcttctcatcagtttgga
accagttttgtcaatggtgcaagtcctagcagcatgatgttaaaccagtttcaagctgct
gctgctgctgccgctgctgccaaaacctcccctccttttcagccagcttcctctagctct
gttcctagtagtgagagcaaggccacacatcaccggagcccagcctctgtacaatgtgtc
cctcgcacccctccaccccttaacatctctttacctctgccacctccattacttgcttca
aattctgctgagcctgcacgtctaccaagcttgtcatctatatccactaatgatgcattt
ttaccaccctgttccactgttcctgtccaatctgctaactccttatctatcaagctagca
tccatgcagcaaaaagcatccttgccttcttttacagtccaccatcagcctttgccctgc
ttggctgtggcacagtccacacccctgatcccacagtccaacacttcaagttcatctgct
atgtgggtcacacttggcatgcagtctccttatgcttcgcacctttctggggtaaagcca
cgataa
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