Hipposideros armiger (great roundleaf bat): 109378365
Help
Entry
109378365 CDS
T04661
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
hai
Hipposideros armiger (great roundleaf bat)
Pathway
hai00562
Inositol phosphate metabolism
hai01100
Metabolic pathways
hai01521
EGFR tyrosine kinase inhibitor resistance
hai04012
ErbB signaling pathway
hai04014
Ras signaling pathway
hai04020
Calcium signaling pathway
hai04062
Chemokine signaling pathway
hai04064
NF-kappa B signaling pathway
hai04066
HIF-1 signaling pathway
hai04070
Phosphatidylinositol signaling system
hai04072
Phospholipase D signaling pathway
hai04360
Axon guidance
hai04370
VEGF signaling pathway
hai04380
Osteoclast differentiation
hai04611
Platelet activation
hai04613
Neutrophil extracellular trap formation
hai04625
C-type lectin receptor signaling pathway
hai04650
Natural killer cell mediated cytotoxicity
hai04662
B cell receptor signaling pathway
hai04664
Fc epsilon RI signaling pathway
hai04666
Fc gamma R-mediated phagocytosis
hai04670
Leukocyte transendothelial migration
hai04722
Neurotrophin signaling pathway
hai04750
Inflammatory mediator regulation of TRP channels
hai04919
Thyroid hormone signaling pathway
hai04933
AGE-RAGE signaling pathway in diabetic complications
hai04935
Growth hormone synthesis, secretion and action
hai05167
Kaposi sarcoma-associated herpesvirus infection
hai05169
Epstein-Barr virus infection
hai05170
Human immunodeficiency virus 1 infection
hai05171
Coronavirus disease - COVID-19
hai05200
Pathways in cancer
hai05205
Proteoglycans in cancer
hai05206
MicroRNAs in cancer
hai05214
Glioma
hai05223
Non-small cell lung cancer
hai05225
Hepatocellular carcinoma
Module
hai_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
hai00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
109378365 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
109378365 (PLCG2)
04014 Ras signaling pathway
109378365 (PLCG2)
04370 VEGF signaling pathway
109378365 (PLCG2)
04064 NF-kappa B signaling pathway
109378365 (PLCG2)
04066 HIF-1 signaling pathway
109378365 (PLCG2)
04020 Calcium signaling pathway
109378365 (PLCG2)
04070 Phosphatidylinositol signaling system
109378365 (PLCG2)
04072 Phospholipase D signaling pathway
109378365 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
109378365 (PLCG2)
04613 Neutrophil extracellular trap formation
109378365 (PLCG2)
04625 C-type lectin receptor signaling pathway
109378365 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
109378365 (PLCG2)
04662 B cell receptor signaling pathway
109378365 (PLCG2)
04664 Fc epsilon RI signaling pathway
109378365 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
109378365 (PLCG2)
04670 Leukocyte transendothelial migration
109378365 (PLCG2)
04062 Chemokine signaling pathway
109378365 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
109378365 (PLCG2)
04919 Thyroid hormone signaling pathway
109378365 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
109378365 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
109378365 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
109378365 (PLCG2)
04380 Osteoclast differentiation
109378365 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109378365 (PLCG2)
05206 MicroRNAs in cancer
109378365 (PLCG2)
05205 Proteoglycans in cancer
109378365 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
109378365 (PLCG2)
05214 Glioma
109378365 (PLCG2)
05223 Non-small cell lung cancer
109378365 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
109378365 (PLCG2)
05171 Coronavirus disease - COVID-19
109378365 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
109378365 (PLCG2)
05169 Epstein-Barr virus infection
109378365 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
109378365 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
109378365 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hai04131
]
109378365 (PLCG2)
Enzymes [BR:
hai01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
109378365 (PLCG2)
Membrane trafficking [BR:
hai04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
109378365 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
109378365 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
SH3_1
SH3_9
PH_12
C2
PH
SH3_2
PH_14
EF-hand_like
Adhesin_E
Motif
Other DBs
NCBI-GeneID:
109378365
NCBI-ProteinID:
XP_019490318
EnsemblRapid:
ENSHARG00000003827
UniProt:
A0A8B7QRG1
LinkDB
All DBs
Position
Unknown
AA seq
1213 aa
AA seq
DB search
MPTMVNVDALPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRQKEDCCFTILYGNQFILSTLSLAADSKEDAT
KWLSGLKILHQEVMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKTVLPMVNFKMSSA
KFLKDKFVEIGAHKDELSFEQFHLFYKKLMFDQQKSILDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFIDEFLMYLFSRENS
IWDEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRYMARV
FKEVFGDLLLMRPTEASADQLPSPSQLREKIIIKHKKLGPRGDIDVNMEDKKDEHKQQGE
LYMWDAIDQKWTRHYCAIADAKLSFSDDIEQTMEDELPQDTPPTELHFGEKWFHKKVEKR
ISAEKLLQEYCNETGGKDGTFLVRESERFPNDYTLSFWRSNRVQHCRIRSTMEGGIMKYY
LTDNLMFTSIYALIQHYRETHLRCADFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDML
MRVPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEISPSMPQRTVKALYDY
KAKQSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTVDVEELEKQII
EDSPLGSLCRGILDLNTYNVVLKLKMVGPKQENNMKYWEKNQSIAIELSDLVVYCKPTSK
TKDNLENPDFREIRSFVETKADSVVRQKPIELLKYNQKGLTRVYPKGQRVDSSNYDPFRL
WLCGSQMVALNFQTADKYMQMNQALFSLNGRTGYVLQPESMRNEKYDPMPPESQRKILMT
LTVKVSPPLLLPGSQGCVALGGCMPVPSDDTCRLVYTILQGHFRGEREGERDLKLMNIEM
VFPGVGWAGQMGPLISFDHLPDDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEEDMFS
DPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLVSGETCWGSLRFI
SWWGWKWPMSIVD
NT seq
3642 nt
NT seq
+upstream
nt +downstream
nt
atgcccaccatggtcaacgtggacgcccttccggaatatgagaagagtcagatcaagaga
gccctggagctgggcacagtgatgaccgtcttcagcttccgcaagtccaccccggagcgg
aggaccgtccaggtgatcatggagacgcggcaggtggcctggagtaagacggctgacaaa
atcgagggcttcttggatatcatggaaataaaggaaatccgcccagggaagaactccaag
gattttgagcgtgcaaaggcagtccgccagaaggaagactgctgttttaccatcttgtat
ggcaaccagttcatcctcagcacactcagtttagcagctgactctaaggaagatgcaact
aagtggctctccggcttgaaaatcttacaccaggaagtgatgagcgcgtcgacacctacc
attatcgagagttggctgagaaagcagatctattctgtggatcaaaccaggagaaacagc
atcagcctccgagagttgaagactgtcttgcctatggtcaacttcaaaatgagcagtgcc
aagttcctcaaagataagtttgtggaaattggcgcgcacaaagatgaactcagctttgaa
cagttccatctcttctataaaaaacttatgtttgaccagcaaaaatcgattcttgatgaa
ttcaagaaagattcctctgtgttcatcttgggcaacactgaccggccggatgcctctgcc
gttcacctgcacgacttccagcggtttctcttacatgaacagcaggagctttgggctcag
gatctgaacaaagtccgggagcgaatgacaaaatttatcgacgacacgatgagggagact
gccgagccttttctgtttatcgatgagttcctcatgtatctgttttcacgggagaacagc
atttgggatgaaaaatatgatgtggtggacatgcaggacatgaacaaccccttgtctcat
tactggatctcctcatcacataacacgtacctcacaggtgaccagctgcggagtgagtca
tccccagaagcatacatccgctgtctgcgcatgggctgtcgctgcattgaactggactgc
tgggatgggccggatgggaagcccatcatctaccacggctggacacggaccacaaagatc
aagtttgatgacgtcgtgcaagccatcaaagaccatgcctttgtgacctcgagcttcccg
gtgatcctgtccattgaggagcactgtagcgtggaacagcagcgctacatggccagagtg
ttcaaagaggtgttcggcgacttgctgctgatgaggcccacggaggccagtgctgaccag
ctgccctcacccagccagctgcgggagaagatcatcatcaagcataagaagctgggcccc
cgaggtgacatagatgtcaatatggaggacaagaaggatgagcacaagcagcagggtgaa
ctgtacatgtgggatgccatcgaccagaaatggactcggcactactgcgccattgcggat
gccaagctgtccttcagcgatgacattgaacagactatggaagacgaactgccccaggat
acccctcccacagagctgcattttggagagaagtggttccataagaaggtggagaagagg
ataagtgctgagaagctgctgcaggaatactgcaacgaaacggggggcaaggatgggacc
ttcttggtgcgggagagcgagaggttccccaatgactacaccctgtccttctggcggtcc
aaccgggttcagcactgccggatccgctccaccatggagggcgggatcatgaagtactac
ctgactgacaacctcatgttcaccagcatctatgccctcatccagcactaccgtgagaca
cacctgcgctgtgccgacttcgagctccggctcactgaccctgtgcccaaccccaacccc
catgaatcaaagccgtggtactacgatgggctgagccgtggagaagcggaggacatgctg
atgagggttccccgggatggggcctttctcatccggaaacgggaaggtagcgactcctac
gccatcaccttcagggccaggggcaaggtgaagcactgtcgcatcaaccgggatggccgg
cactttgtgctggggacctccgcctacttcgagagtctggtggagctcgtcagttactac
gagaagcacgcgctctaccgaaagatgagactgcgctaccccgtgacccctgagctcctg
gaacgctacaatatggaaagagatataaactccctgtatgacgtcagcagaatgtatgtg
gatcccagtgaaatcagcccttctatgcctcagagaaccgtgaaagctctgtatgactac
aaagccaagcagagtgatgagctgagcttctgccgtggtgccctcattcacaacgtctcc
aaggagcccgggggctggtggaaaggagactatggaaccagaatccaacagtacttcccg
tcgaattacgtcgaggacatttccacagttgacgtggaggagctggagaaacagattatt
gaagacagtcctttagggagtctttgcagaggaatactggatctcaacacctataacgtt
gtactgaaactaaagatggttggccccaaacaggaaaacaacatgaagtactgggagaag
aaccagtccatcgccatcgaactctcggacctggtcgtctactgcaaaccaaccagcaag
accaaggacaatttagaaaaccctgacttccgagaaatccgctcctttgtggagacgaag
gctgacagcgtcgtcagacagaaacccatcgagctcctgaagtacaatcaaaagggcctg
acccgcgtgtacccgaagggacagagggtggactcctccaactacgatcccttccgcctc
tggctctgcggctcccaaatggtggcgctcaatttccagactgcagataaatacatgcag
atgaaccaggccctgttttcacttaatgggcggacgggctacgtcctacagcctgagagc
atgaggaatgagaaatacgaccccatgccgcccgagtcccagagaaagatcctgatgact
ctgacggtcaaggtaagcccccctctcctcctcccagggagtcagggctgtgtggcattg
ggagggtgcatgcctgtacctagtgatgatacctgtcgtcttgtttacaccatcctccag
ggtcattttagaggggaaagggagggggagagagatttaaagctgatgaatatagagatg
gtttttccaggagtggggtgggcaggacaaatggggcctctaataagctttgatcacctt
ccagacgacaatggcctaagcccagtttgggctccaacacaggagaaggtgacatttgaa
atttatgacccaaacctcgcatttctgcgctttgtggtgtatgaggaagatatgttcagc
gatcccaactttctggctcatgctacttaccccattaaaggcatcaaatcaggatttaga
tctgttcctctgaagaacgggtacagcgaagacattgagctggcttccctcctggttttc
tgtgagatgcggccagtcctggtgagtggagaaacgtgttggggttccctgagatttatc
agctggtgggggtggaagtggcccatgagtatagttgactga
DBGET
integrated database retrieval system
