Haloferax alexandrinus: G3A49_10670
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Entry
G3A49_10670 CDS
T06450
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
hale
Haloferax alexandrinus
Pathway
hale00290
Valine, leucine and isoleucine biosynthesis
hale00660
C5-Branched dibasic acid metabolism
hale01100
Metabolic pathways
hale01110
Biosynthesis of secondary metabolites
hale01210
2-Oxocarboxylic acid metabolism
hale01230
Biosynthesis of amino acids
Module
hale_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
hale_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
hale00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
G3A49_10670 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
G3A49_10670 (leuC)
Enzymes [BR:
hale01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
G3A49_10670 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
G3A49_10670 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
QIB78576
UniProt:
A0A6C0USW3
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Position
complement(2154412..2155833)
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AA seq
473 aa
AA seq
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MSEGTLYDKVWEEHTVSELPTGQTQLFCGLHLIHEVTSPQAFGMLQERDLEVAYPNRTHA
TVDHIVPTSDQSRPFRDDAAEEMMAELEQNVREAGINFSDPTSGEQGIVHVIGPEKGLTQ
PGMTIVCGDSHTSTHGAFGALAFGIGTSQIRDVLATQTVAMEKKKVRKIEVTGELGPGVE
AKDVILEIIRRLGTEGGVGYVYEYAGEAIENLDMEGRMSICNMSIEGGARAGYVNPDETT
YEWLKETEYFQENPERFDELKPYWESIRSDEDAEYDDVVTIDGSELEPVVTWGTTPGQGV
GITQPIPAPEDLPEEKQDTARMAQEHMGVTPGETMEGYEIDVAFLGSCTNARLPDLRRAA
GVVKGRQVADSVRAMVVPGSQRVKAAAEAEGLDEIFKDAGFEWREAGCSMCLGMNEDQLE
GDEASASSSNRNFIGRQGSKDGRTVLMNPRMVAAAAVTGEVTDVRELKEVTTV
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgagtgagggaacgctgtacgacaaggtctgggaggaacacacggtttcggagctgccg
accggccagacgcagctgttctgcggcctgcacctcatccacgaggtgacgagtccgcag
gcgttcggcatgttgcaggaacgcgacctcgaagtcgcctacccgaaccggacgcacgcg
acggtcgaccacatcgtccccacgtcggaccagtcgcggccgttccgcgacgacgccgcc
gaggagatgatggccgaactggagcagaacgtccgcgaagcgggcatcaacttctcggac
cccacgtcgggcgagcagggtatcgtccacgtcatcgggcccgagaagggactcacccag
cccggcatgaccatcgtctgcggcgacagccacacctcgacccacggcgcgttcggcgcg
ctcgcgttcggtatcgggacgagccagattcgcgacgtgctggcgacccagaccgtcgcg
atggagaagaagaaggtgcggaaaatcgaggtcacgggcgaactcggccccggcgtcgaa
gcgaaggacgtcatcctcgaaatcatccgtcgcctcggcaccgaaggcggcgtcggctac
gtctacgagtacgccggcgaggccatcgagaacctcgacatggagggccggatgagcatc
tgtaacatgtccatcgagggcggcgctcgcgcgggctacgtcaaccccgacgagaccacc
tacgagtggctgaaagagaccgagtacttccaggagaaccccgagcggttcgacgaactc
aagccgtactgggagtccatccgctccgacgaggacgccgagtacgacgacgtcgtcacc
atcgacggctccgaactcgaacccgtcgtgacgtgggggaccacgcccggacagggcgtc
ggcatcacccagccgattccggcccccgaagacctgcccgaggagaagcaggacaccgcc
cggatggcgcaggaacacatgggcgtcacgcccggcgagacgatggagggctacgaaatc
gacgtggcgttcctcggctcgtgtacgaacgctcgcctgcccgacctccgccgcgcggcg
ggggtcgtgaagggtcgacaggtcgcggacagcgtccgcgcgatggtcgtccccggcagt
cagcgcgtcaaggccgccgccgaagcggagggcctcgacgagatattcaaggacgccggc
ttcgagtggcgcgaggcgggctgttcgatgtgtctcggcatgaacgaggaccaactggag
ggcgacgaggcctccgcgtcctcgtcgaaccgcaacttcatcggccggcaggggtcgaaa
gacggccgcaccgtcctgatgaacccgcgcatggtcgccgcggcggccgtcaccggggaa
gtgactgacgtacgcgaactgaaggaggtgaccacggtatga
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