Heterocephalus glaber (naked mole-rat): 101720924
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Entry
101720924 CDS
T02812
Symbol
Adam17
Name
(RefSeq) ADAM metallopeptidase domain 17
KO
K06059
disintegrin and metalloproteinase domain-containing protein 17 [EC:
3.4.24.86
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04148
Efferocytosis
hgl04330
Notch signaling pathway
hgl04668
TNF signaling pathway
hgl05010
Alzheimer disease
hgl05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
101720924 (Adam17)
04668 TNF signaling pathway
101720924 (Adam17)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101720924 (Adam17)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
101720924 (Adam17)
09164 Neurodegenerative disease
05010 Alzheimer disease
101720924 (Adam17)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hgl01002
]
101720924 (Adam17)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
hgl04090
]
101720924 (Adam17)
Enzymes [BR:
hgl01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.86 ADAM 17 endopeptidase
101720924 (Adam17)
Peptidases and inhibitors [BR:
hgl01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
101720924 (Adam17)
CD molecules [BR:
hgl04090
]
Proteins
101720924 (Adam17)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Reprolysin_5
Reprolysin_2
ADAM17_MPD
Disintegrin
Reprolysin_3
Reprolysin
Reprolysin_4
Pep_M12B_propep
Motif
Other DBs
NCBI-GeneID:
101720924
NCBI-ProteinID:
XP_012924925
UniProt:
G5BEK2
LinkDB
All DBs
Position
Un
AA seq
838 aa
AA seq
DB search
MRQRLLFLASLVLLVLAPRPPDASGSGSHQRLERLDSLLSDYDILSLSSIQQHSVRKRDL
QASAHLETLLTFSALKRHFKLYLTSSTERFSQNFKVMVVDGKAESEYAVSWQDFFSGHVV
GEPDSRVLAHIGDDDVTIRINTDGAEYNIEPLWRFVNDTKDKRMLAYRSEDIKNVSRLQS
PKVCGYVKVEDEELIPEGLIDREPPGEFVHRVKRRADPDPMKNTCKLLVVADHRFYKYMG
RGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVRPGERHYNM
AKSYPHEEKDSWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANS
HGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDAL
PECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGN
SRVDEGEECDPGIMYLNNDTCCNSDCTLKPGVQCSDRNSPCCKNCQFETAQKRCQEAINA
TCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSC
KVCCRDPSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDMIERFWDFIDQLS
INTFGKFLADNIVGSVLVFSLLFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMD
SASVRIIKPFPAPQTPGRLQPLPPGPVMLPMSAALKLEHQRMDTIQEDPTPTLTRTPTRT
RTASHADEDGLDKDPFPTSSTAAKSFEDLTDHPATRSEKAASFRLQRQSRVDSKETEC
NT seq
2517 nt
NT seq
+upstream
nt +downstream
nt
atgaggcagcgtcttctcttcctggccagcttggttcttctcgtgctggcgccacgaccc
ccggacgcgtcgggctccggctcccaccagcgactcgagaggctggattctttgctctca
gactacgacatcctctctttatctagcatccagcagcactctgtaaggaagagggatctt
caggcttcagcacatttagaaacactactaactttttcagctttgaaaaggcattttaaa
ctgtatctaacatcaagtactgagcgcttttcacaaaatttcaaagtcatggtggtggat
ggcaaagcggaaagcgagtatgcagtcagttggcaggacttcttcagcggccacgtggtc
ggtgagcctgactccagggtcctggcccacataggagatgatgatgttaccataaggatc
aacacagatggggcagagtataacatagagccactttggagatttgttaatgatactaaa
gacaaaaggatgctagcttacagatccgaagacatcaagaatgtttcgcgcttgcagtct
cccaaagtatgtggctatgtgaaagtggaagacgaggagctgattccggaagggctgata
gacagggagccgcctggagagtttgtccatcgggtgaagagaagagccgacccggatccc
atgaagaacacgtgtaaactactggtggttgcagatcatcgcttttacaagtacatgggc
cgaggggaggagagcaccacgaccaattacctgatagagctaattgacagagttgatgac
atctaccggaacacttcgtgggataatgcaggctttaaaggttatggaatacaaatagag
cagattcgcattctcaagtctccacaagaggtcagacctggcgaaaggcactacaacatg
gcgaagagttacccgcatgaagagaaggactcatgggatgtgaagatgctattggagcaa
tttagctttgatatagccgaggaagcatcaaaagtctgcttggcccaccttttcacgtac
caggattttgacatgggaacacttggactggcctacgtgggttctcccagagcgaacagt
catggaggcgtctgtcctaaagcttattatagtccagttgggaagaaaaatatctatttg
aatagtggtttgaccagcacaaaaaattatggtaaaaccatcctcacaaaggaagcggac
ctggtcaccactcacgaactggggcacaacttcggagcagaacacgatccggacgcccta
cctgaatgcgcgcccaacgaagaccagggtgggaagtatgtgatgtaccccattgccgtg
agcggcgatcacgagaataacaagatgttttccaactgcagtaagcagtccatctataag
accattgagagcaaggcccaggagtgcttccaggagcgcagcaacaaggtgtgcggcaac
tccagggtggatgagggggaagagtgtgaccctgggatcatgtacctcaacaacgacacc
tgctgcaacagtgactgcacgctgaagccgggtgtgcagtgcagtgacaggaacagtccg
tgctgtaagaactgccagttcgagacggcccagaagcggtgccaggaggccatcaatgct
acctgcaagggcgtgtcctattgcacagggaacagcagcgagtgccccccacctgggaac
gcggaggatgacacggtctgcctggatctgggcaagtgcaaggacgggaagtgcatcccc
ttctgcgagcgcgagcagcagctggagtcctgcgcctgcaatgaaaccgacaactcctgc
aaggtgtgctgccgggacccgtctggccggtgtgtgccttacgttgacgctgagcagaag
aacttatttttgaggaaagggaagccgtgtacagtaggcttctgcgacatgaacggcaaa
tgtgagaaacgagtacaggacatgatcgagcggttctgggacttcattgaccagctgagc
atcaacacatttgggaaatttttagcagacaacatcgtggggtccgtcctggttttctcc
ttgctgttctggattcccttcagcattcttgtccattgtgtggataagaagctggataag
cagtatgagtctctgtccctgttccaccccagcaacgtggagatgctgagcagcatggac
tcggcctctgtgcgcatcatcaagcctttccccgccccccagaccccaggccgcctgcag
ccactgcccccaggccccgtgatgctgcccatgtctgccgccctgaagctggagcaccag
aggatggacacaatccaggaggaccccacgccgactctcacgcggactcccacacggacg
aggacggcctcgcatgcggacgaggacggcctggacaaggacccgttccccaccagtagc
acggctgccaagtccttcgaggacctcacagaccacccggccacccggagcgagaaggca
gcgtccttcaggctccagcggcagagccgcgtggacagcaaggagacggagtgctag
DBGET
integrated database retrieval system
