Halomonas hydrothermalis: CLM76_14170
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Entry
CLM76_14170 CDS
T05117
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
hhh
Halomonas hydrothermalis
Pathway
hhh00290
Valine, leucine and isoleucine biosynthesis
hhh00660
C5-Branched dibasic acid metabolism
hhh01100
Metabolic pathways
hhh01110
Biosynthesis of secondary metabolites
hhh01210
2-Oxocarboxylic acid metabolism
hhh01230
Biosynthesis of amino acids
Module
hhh_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
hhh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CLM76_14170 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CLM76_14170 (leuC)
Enzymes [BR:
hhh01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CLM76_14170 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
CLM76_14170 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ATH78658
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Position
3029319..3030770
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AA seq
483 aa
AA seq
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MSGQTLYDKLWNQHLVKQRDDGTALIYIDRQLLHEVTSPQAFEGLRLANRKPWRLDANLA
TPDHNVPTTVKERAEGNSGIKDPVSLIQVQTLDDNCQAFGIEEFKINDPRQGIVHVVGPE
QGATLPGMTVVCGDSHTATHGAFAALAHGIGTSEVEHVLATQCLLAQKMKNMQVRVEGEL
GLGVTAKDVVLAIIGKIGTAGGTGYAIEFAGSAIESLSMEGRMTVCNMAIEAGARVGLIA
VDDTTIDYLAERPFAPTAEQWEAAVADWRLLVSDADAHFDKVVTLKAEEIEPQVSWGTSP
EMVTGISGQVPDPQAADDETVQRSHSRALEYMGLQANQKITDIKLDKVFIGSCTNSRIED
LREAAKVAKGNKVADTIKLAMVVPGSGLVKRQAEAEGLDKIFIEAGFEWREPGCSMCLAM
NADKLGAGEHCASTSNRNFEGRQGYGGRTHLVSPAMAAAAAIAGHFVDVRTLPANDATHA
QEA
NT seq
1452 nt
NT seq
+upstream
nt +downstream
nt
atgtcaggtcaaaccctttacgacaaactctggaaccagcacttggtcaagcagcgcgat
gacggcacagcgctgatctacatcgaccgccaactgctccacgaagtgacctcgccacag
gcgtttgaaggcctgcgtctggccaaccgcaagccctggcgtctggatgccaacctggcc
acccccgatcacaacgtgcctaccactgtgaaagagcgtgccgagggcaacagcggcatc
aaggacccggtctcgttgattcaggtgcagaccctggacgacaactgccaggccttcggt
atcgaagaattcaagatcaacgacccccgccagggcatcgtgcacgtggtgggccccgag
cagggtgccacactgcccggcatgaccgtggtgtgcggcgactcgcataccgccacccac
ggcgcctttgccgcgctggcccatggtattggcacttcggaagtggaacacgtgctggct
acccagtgtttgctggcgcagaagatgaagaacatgcaggtgcgcgtggaaggcgagctg
ggtctgggcgtgaccgccaaggacgtggtgctggccatcatcggcaagattggtaccgcc
ggcggcaccggctatgccatcgagtttgctggaagcgccatcgaatcgctctccatggaa
ggccgcatgaccgtgtgcaacatggccatcgaagcgggtgcccgagtggggctgattgcg
gtcgacgacaccaccatcgattacctcgccgagcgcccctttgcgcccaccgccgagcag
tgggaagccgccgtggccgactggcgtctgctggtctctgatgccgatgcccacttcgat
aaagtggtcaccctgaaggccgaagagatcgagcctcaggtaagctggggcaccagccct
gaaatggtcaccggtatttccggtcaggtgcccgacccccaggccgccgatgacgaaacc
gtccagcgcagccactcccgcgcgctggagtacatgggcctgcaggccaaccagaaaatt
accgatatcaagctggacaaggtgttcatcggctcctgcaccaactcgcgtatcgaagac
ctgcgtgaagccgccaaggtggccaagggcaacaaggtagccgataccatcaagctggcc
atggtggtgccgggttctggcctggtgaagcgccaggcggaagccgaaggcctcgacaag
atcttcatcgaagcgggcttcgagtggcgcgagccgggttgctccatgtgcttggccatg
aatgccgacaagctgggcgctggcgagcactgcgcctcgacctccaaccgtaacttcgaa
ggtcgtcaggggtacggcgggcgtacgcacctggtgagcccggccatggccgctgcggcc
gccattgctggccacttcgtcgatgtccgtaccttgcctgccaacgatgccacccacgcc
caggaggcctga
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