Hyaena hyaena (striped hyena): 120241963
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Entry
120241963 CDS
T07257
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv00010
Glycolysis / Gluconeogenesis
hhv00020
Citrate cycle (TCA cycle)
hhv00620
Pyruvate metabolism
hhv00785
Lipoic acid metabolism
hhv01100
Metabolic pathways
hhv01200
Carbon metabolism
hhv01210
2-Oxocarboxylic acid metabolism
hhv04066
HIF-1 signaling pathway
hhv04922
Glucagon signaling pathway
hhv05230
Central carbon metabolism in cancer
hhv05415
Diabetic cardiomyopathy
Module
hhv_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
120241963 (PDHA1)
00020 Citrate cycle (TCA cycle)
120241963 (PDHA1)
00620 Pyruvate metabolism
120241963 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
120241963 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
120241963 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
120241963 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
120241963 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
120241963 (PDHA1)
Enzymes [BR:
hhv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
120241963 (PDHA1)
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Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
120241963
NCBI-ProteinID:
XP_039103316
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGHHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgcagctgtctcccgcgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgatcttcaccgactggaagagggccctcctgtcaccacagtgctcaccagagaagat
gggctcaaatactataggatgatgcagactgttcgccgaatggaattaaaggcagatcag
ctgtataaacagaaaattattcgtggtttttgtcacttgtgtgatggtcaggaagcttgc
tgtgtgggcctggaggccggcataaatcccacagaccatcttatcacagcctatcgggct
catggatttaccttcacgcgtgggctttctgtccgagaaattctcgcagagcttacagga
cgaagaggaggctgtgctaaaggaaaaggtggatcgatgcatatgtatgccaaaaacttc
tacgggggcaatggcatcgttggagctcaggtgcccctgggagcagggattgctctggcc
tgtaagtataacggaaaggatgaggtctgtttgactttatatggcgatggtgctgctaat
caaggtcagatattcgaagcttacaatatggcagctttgtggaaattgccttgtattttc
atctgtgaaaataaccgctatggaatgggaacgtccgttgagagagcagcggccagcact
gattactacaagagaggtgacttcattcctgggctgcgggtagatggaatggatatcctg
tgtgtccgggaggcgacaaagtttgcagccgcctactgtagatctggaaagggtcccata
ctgatggagctacagacttaccgctaccatggacacagcatgagtgaccctggtgtcagt
taccgtacacgagaggagattcaggaagtaagaagcaagagtgacccgattatgcttctc
aaggatagaatggtgaacagcaatctggctagtgttgaagaattaaaggaaatcgatgtt
gaagtcaggaaagaaattgaggatgctgcccagtttgccactgctgatcctgaaccaccg
ttggaagaactaggccatcacatttacagcagcgacccgccttttgaagttcggggtgcg
aatcagtggatcaagtttaagtccatcagttaa
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