Halorubrum lacusprofundi: Hlac_0872
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Entry
Hlac_0872 CDS
T00856
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
hla
Halorubrum lacusprofundi
Pathway
hla00290
Valine, leucine and isoleucine biosynthesis
hla00660
C5-Branched dibasic acid metabolism
hla01100
Metabolic pathways
hla01110
Biosynthesis of secondary metabolites
hla01210
2-Oxocarboxylic acid metabolism
hla01230
Biosynthesis of amino acids
Module
hla_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
hla_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
hla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Hlac_0872
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Hlac_0872
Enzymes [BR:
hla01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Hlac_0872
4.2.1.35 (R)-2-methylmalate dehydratase
Hlac_0872
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Motif
Pfam:
Aconitase
DUF3944
Motif
Other DBs
NCBI-ProteinID:
ACM56470
UniProt:
B9LUZ3
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Position
1:complement(860477..861898)
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AA seq
473 aa
AA seq
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MSEGTLYDKVWDRHTVTKLPTGQDQLFVGLHLVHEVTSPQAFGMLKERDQEVAFPERTHA
TVDHIVPTGNRDRPYRDEAAENMMAELEANVRGSGIDFSDPDSGNQGIVHVIGPEQGLTQ
PGMTIVCGDSHTSTHGAFGALAFGIGTSQIRDVLATGCIAMEKQQVRKIEVTGELGEGVT
AKDVILTIIGKLGTDGGVGYVYEYAGEAIEDLGMEGRMSICNMSIEGGARAGYVNPDETT
YEWLAETDAFADDPEKFERLKPYWESIRSDADAEYDDVVTIDGSAIEPTVTWGTTPGQTA
GITEPIPDPDDLPEEDRDTAKRAQKHMRVEPGDTMEGYDIDVAFLGSCTNARLKDLREAA
AFVEGREVDDDVRAMVVPGSQRVRDAAEAEGIDEIFIEAGFDWREPGCSMCLGMNDDQLV
GDEASASSSNRNFVGRQGSKDGRTVLMSPIMVAAAAVTGEVTDVREMEEVATV
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgagcgaggggaccctgtacgacaaggtgtgggaccggcacacggtgacgaagctgccc
accggacaggaccagctgttcgtcgggctccacctcgttcacgaggtcaccagcccgcag
gcgttcggcatgctgaaagagcgcgaccaagaggtggcgttcccggagcgcacgcacgcg
accgtcgaccacattgtgccgactgggaaccgcgatcggccctaccgcgacgaggccgcc
gagaacatgatggcggagctggaggcgaacgtccgcggctcgggcatcgacttttccgat
ccggactccggcaaccaggggatcgtccacgttatcgggccggagcaggggctcacccag
ccgggaatgacgatcgtctgtggcgactcgcacacgtcgacgcacggcgcgttcggcgcg
ctggcgttcggcatcggcacctcgcagatccgcgacgtgctcgcgacgggctgtatcgcc
atggagaaacagcaggtccgcaagatcgaggtcacgggcgagctcggcgagggcgtcacc
gcgaaggacgtcatcctgacgatcatcgggaagctcgggaccgacggcggcgtcggctac
gtctacgagtacgccggcgaggccatcgaggacctcgggatggaagggcggatgtccatc
tgtaacatgtcgatcgaaggcggcgcccgcgcgggatacgtcaaccccgacgagaccacc
tacgagtggctcgcggagacggacgccttcgccgacgaccccgagaagttcgagcggctg
aaaccctactgggagtcgatccggagcgacgccgacgccgagtacgacgacgtggtcacc
atcgacggctcggcgatcgaaccgaccgtcacgtgggggaccacgcccggtcagaccgcg
ggcatcaccgagccgatcccggatcccgacgacctgcccgaggaggaccgcgacaccgcg
aagcgggcacagaaacacatgcgcgtcgagcccggcgacacgatggaggggtacgacatc
gacgtggcgttcctcggctcgtgtactaacgcgcggctgaaggacctccgcgaggccgcg
gcgttcgtcgagggtcgcgaggtcgacgacgacgtgcgcgcgatggtcgtccccggtagc
cagcgcgtccgcgacgccgccgaggccgaagggatagacgagatattcatcgaggccggc
ttcgactggcgcgagcccggctgttcgatgtgtctcggcatgaacgacgaccagctggtg
ggcgacgaggcgagcgcctcctcgtcgaaccggaacttcgtcggccgacagggctcgaag
gacgggcgcaccgtgctgatgagtccgatcatggtcgcggccgcggcggtgaccggcgag
gtcaccgacgtccgcgagatggaggaggtggcgaccgtatga
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