Homo sapiens (human): 136 Help Entry 136               CDS       T01001                                  Symbol ADORA2B, ADORA2 Name (RefSeq) adenosine A2b receptor   KO K04267   adenosine receptor A2b Organism hsa  Homo sapiens (human) Pathway hsa04015   Rap1 signaling pathway hsa04020   Calcium signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04270   Vascular smooth muscle contraction hsa05034   Alcoholism Drug target Adenosine (DG00243):  D00045<JP/US> D02300<JP> D02769 D08646 D08647 Aminophylline (DG01062):  D00227 D05429<JP> D11630<US> Diprophylline:  D00691<JP> Enprofylline:  D04006 Etrumadenant:  D12369 Proxyphylline:  D01771<JP> Theophylline (DG01061):  D00371<JP/US> D01712 D06103 D06104 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     136 (ADORA2B)    04020 Calcium signaling pathway     136 (ADORA2B)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     136 (ADORA2B)  09150 Organismal Systems   09153 Circulatory system    04270 Vascular smooth muscle contraction     136 (ADORA2B)  09160 Human Diseases   09165 Substance dependence    05034 Alcoholism     136 (ADORA2B)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     136 (ADORA2B) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Base and nucleoside    Adenosine     136 (ADORA2B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7tm_4 GPR_Gpa2_C 7TM_GPCR_Srx 7TM_GPCR_Sri Motif Other DBs NCBI-GeneID:  136 NCBI-ProteinID:  NP_000667 OMIM:  600446 HGNC:  264 Ensembl:  ENSG00000170425 UniProt:  P29275 Structure PDB LinkDB All DBs Position 17:15850362..15975746 Genome browser AA seq 332 aa AA seqDB search MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT FHKIISRYLLCQADVKSGNGQAGVQPALGVGL NT seq 999 nt NT seq  +upstreamnt  +downstreamnt atgctgctggagacacaggacgcgctgtacgtggcgctggagctggtcatcgccgcgctt tcggtggcgggcaacgtgctggtgtgcgccgcggtgggcacggcgaacactctgcagacg cccaccaactacttcctggtgtccctggctgcggccgacgtggccgtggggctcttcgcc atcccctttgccatcaccatcagcctgggcttctgcactgacttctacggctgcctcttc ctcgcctgcttcgtgctggtgctcacgcagagctccatcttcagccttctggccgtggca gtcgacagatacctggccatctgtgtcccgctcaggtataaaagtttggtcacggggacc cgagcaagaggggtcattgctgtcctctgggtccttgcctttggcatcggattgactcca ttcctggggtggaacagtaaagacagtgccaccaacaactgcacagaaccctgggatgga accacgaatgaaagctgctgccttgtgaagtgtctctttgagaatgtggtccccatgagc tacatggtatatttcaatttctttgggtgtgttctgcccccactgcttataatgctggtg atctacattaagatcttcctggtggcctgcaggcagcttcagcgcactgagctgatggac cactcgaggaccaccctccagcgggagatccatgcagccaagtcactggccatgattgtg gggatttttgccctgtgctggttacctgtgcatgctgttaactgtgtcactcttttccag ccagctcagggtaaaaataagcccaagtgggcaatgaatatggccattcttctgtcacat gccaattcagttgtcaatcccattgtctatgcttaccggaaccgagacttccgctacact tttcacaaaattatctccaggtatcttctctgccaagcagatgtcaagagtgggaatggt caggctggggtacagcctgctctcggtgtgggcctatga

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