Homo sapiens (human): 1856
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Entry
1856 CDS
T01001
Symbol
DVL2
Name
(RefSeq) dishevelled segment polarity protein 2
KO
K02353
segment polarity protein dishevelled
Organism
hsa
Homo sapiens (human)
Pathway
hsa04150
mTOR signaling pathway
hsa04310
Wnt signaling pathway
hsa04330
Notch signaling pathway
hsa04390
Hippo signaling pathway
hsa04550
Signaling pathways regulating pluripotency of stem cells
hsa04916
Melanogenesis
hsa04934
Cushing syndrome
hsa05010
Alzheimer disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05165
Human papillomavirus infection
hsa05200
Pathways in cancer
hsa05217
Basal cell carcinoma
hsa05224
Breast cancer
hsa05225
Hepatocellular carcinoma
hsa05226
Gastric cancer
Network
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06181
Salmonella
nt06215
WNT signaling (cancer)
nt06260
Colorectal cancer
nt06261
Gastric cancer
nt06263
Hepatocellular carcinoma
nt06270
Breast cancer
nt06271
Endometrial cancer
nt06274
Thyroid cancer
nt06505
WNT signaling
Element
N00056
Wnt signaling pathway
N00059
FZD7-overexpression to Wnt signaling pathway
N00060
LRP6-overexpression to Wnt signaling pathway
N01427
WNT5A-ROR signaling pathway
N01444
NXN mutation to WNT5A-ROR signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
1856 (DVL2)
04330 Notch signaling pathway
1856 (DVL2)
04390 Hippo signaling pathway
1856 (DVL2)
04150 mTOR signaling pathway
1856 (DVL2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
1856 (DVL2)
09150 Organismal Systems
09152 Endocrine system
04916 Melanogenesis
1856 (DVL2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
1856 (DVL2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
1856 (DVL2)
05226 Gastric cancer
1856 (DVL2)
05217 Basal cell carcinoma
1856 (DVL2)
05224 Breast cancer
1856 (DVL2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
1856 (DVL2)
09164 Neurodegenerative disease
05010 Alzheimer disease
1856 (DVL2)
05022 Pathways of neurodegeneration - multiple diseases
1856 (DVL2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
1856 (DVL2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dsh_C
Dishevelled
DIX
DEP
PDZ
PDZ_6
Shufflon_N
Motif
Other DBs
NCBI-GeneID:
1856
NCBI-ProteinID:
NP_004413
OMIM:
602151
HGNC:
3086
Ensembl:
ENSG00000004975
UniProt:
O14641
Structure
PDB
LinkDB
All DBs
Position
17:complement(7225342..7234517)
Genome browser
AA seq
736 aa
AA seq
DB search
MAGSSTGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSM
DQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPL
PPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTG
GPSRLERHLAGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRHRRRR
KQRPPRLERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIM
KGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQ
AYFTLPRNEPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITSGSSLPDGCEGRGLSVH
TDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYAS
GLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLP
GATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGG
AGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTSDGGPPPSRGSTGGAPNLRA
HPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPELTASRQS
FHMAMGNPSEFFVDVM
NT seq
2211 nt
NT seq
+upstream
nt +downstream
nt
atggcgggtagcagcactgggggcggtggggttggggagacgaaggtgatttaccacctg
gatgaggaagagactccctacctggtgaagatccctgtccccgccgagcgcatcaccctc
ggcgatttcaagagcgtcctgcagcggcccgcgggcgccaagtactttttcaagtctatg
gatcaggatttcggggtggtgaaggaagaaatttcagatgacaacgcccgcctcccctgc
ttcaacggaagggtggtatcctggctggtgtcctcagataatccccaacccgagatggcc
cctccagtccatgagcctcgggcagaactggcgcctccagccccacctttacctcctttg
ccacccgagaggaccagcggcattggggactcaaggcctccatccttccaccctaatgtg
tccagcagccatgagaatctggagcctgagacagaaaccgagtcagtagtgtcactgagg
cgggagcggcctcgcaggagagacagcagtgagcatggcgctgggggccacaggactggt
ggcccctcaaggctggagcgccacctggccggatacgagagctcctctaccctcatgacc
agcgagctggagagtaccagcctgggggactcggacgaggaggacaccatgagcaggttc
agcagctccacggagcagagcagtgcctcccgcctccttaagcgccaccggcggcgaagg
aagcagaggccaccccgcctggagaggacgtcatccttcagcagcgtcacagattccaca
atgtctctcaatatcatcacagtcacgctaaacatggagaagtacaacttcctgggtatc
tccattgttggccagagcaatgagcggggagacggaggcatctacattggctccatcatg
aagggtggggctgtggcggccgacgggcgcattgagccaggggacatgcttttgcaggtg
aatgacatgaactttgagaacatgagcaacgatgacgctgtgcgggtgctgagggacatt
gtgcacaagcctggccccattgtgctgactgtggccaagtgctgggatccctctcctcag
gcctatttcactctcccccgaaatgagcccatccagccaattgaccctgctgcctgggtg
tcccattccgcggctctgactggcaccttcccagcctatccaggttcctcctccatgagc
accattacatctggatcgtctttgcctgatggctgtgaaggccggggtctctccgtccat
acggacatggcatcggtgaccaaggccatggcagctccagagtctggactggaagtccgg
gaccgcatgtggctcaagatcaccatccctaatgcctttctgggctcggatgtggttgac
tggctctaccatcacgtggagggctttcctgagcggcgggaggcccgcaagtatgccagc
gggctgctcaaagcaggcctgatccgacacaccgtcaacaagatcaccttctctgagcag
tgctattacgtcttcggagacctcagtggtggctgtgagagctacctagtcaacctgtct
ctcaatgacaacgatggctccagtggggcttcagaccaggataccctggctcctctgcct
ggggccaccccctggcccctgctgcccactttctcctaccaataccctgccccacacccc
tacagcccgcagcctccaccctaccatgagctttcatcttacacctatggtgggggcagt
gccagcagccagcatagtgagggcagccggagcagtgggtcgacacggagtgatgggggg
gcagggcgcacggggaggcccgaggagcgggcccccgagtccaagtccggcagtggcagt
gagtctgagccctccagccgagggggcagccttcggcggggtggggaagcaagtgggact
agcgatgggggccctcctccatccagaggctcaactgggggtgcccctaatctccgagcc
cacccagggctccatccctatggaccgccccctggcatggccctcccctacaaccccatg
atggtggtcatgatgcccccacctccacctccagtccctccagcagtgcagcctccgggg
gcccctccagtcagagacctgggctctgtgcccccagaactgacagccagccgccaaagc
ttccacatggccatgggcaatcccagcgagttctttgtggatgttatgtag
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