Homo sapiens (human): 388743
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Entry
388743 CDS
T01001
Symbol
CAPN8, nCL-2
Name
(RefSeq) calpain 8
KO
K08577
calpain-8 [EC:3.4.22.-]
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
388743 (CAPN8)
Peptidases and inhibitors [BR:
hsa01002
]
Cysteine peptidases
Family C2: calpain family
388743 (CAPN8)
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Gene cluster
GFIT
Motif
Pfam:
Peptidase_C2
Calpain_III
EF-hand_1
EF-hand_6
EF-hand_7
EF-hand_5
Motif
Other DBs
NCBI-GeneID:
388743
NCBI-ProteinID:
NP_001137434
OMIM:
618777
HGNC:
1485
Ensembl:
ENSG00000203697
UniProt:
A6NHC0
Structure
PDB
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All DBs
Position
1:complement(223541616..223665701)
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AA seq
703 aa
AA seq
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MAAQAAGVSRQRAATQGLGSNQNALKYLGQDFKTLRQQCLDSGVLFKDPEFPACPSALGY
KDLGPGSPQTQGIIWKRPTELCPSPQFIVGGATRTDICQGGLGDCWLLAAIASLTLNEEL
LYRVVPRDQDFQENYAGIFHFQFWQYGEWVEVVIDDRLPTKNGQLLFLHSEQGNEFWSAL
LEKAYAKLNGCYEALAGGSTVEGFEDFTGGISEFYDLKKPPANLYQIIRKALCAGSLLGC
SIDVSSAAEAEAITSQKLVKSHAYSVTGVEEVNFQGHPEKLIRLRNPWGEVEWSGAWSDD
APEWNHIDPRRKEELDKKVEDGEFWMSLSDFVRQFSRLEICNLSPDSLSSEEVHKWNLVL
FNGHWTRGSTAGGCQNYPATYWTNPQFKIRLDEVDEDQEESIGEPCCTVLLGLMQKNRRW
RKRIGQGMLSIGYAVYQVPKELESHTDAHLGRDFFLAYQPSARTSTYVNLREVSGRARLP
PGEYLVVPSTFEPFKDGEFCLRVFSEKKAQALEIGDVVAGNPYEPHPSEVDQEDDQFRRL
FEKLAGKDSEITANALKILLNEAFSKRTDIKFDGFNINTCREMISLLDSNGTGTLGAVEF
KTLWLKIQKYLEIYWETDYNHSGTIDAHEMRTALRKAGFTLNSQVQQTIALRYACSKLGI
NFDSFVACMIRLETLFKLFSLLDEDKDGMVQLSLAEWLCCVLV
NT seq
2112 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccaggcagctggtgtatctaggcagcgggcagccactcaaggtcttggctcc
aaccaaaacgctttgaagtacttgggccaggatttcaagaccctgaggcaacagtgcttg
gactcaggggtcctatttaaggaccctgagttcccagcatgtccatcagctttgggctac
aaggatcttggaccaggctctccgcaaactcaaggcatcatctggaagcggcccacggag
ttgtgtcccagccctcagtttatcgttggtggagccacgcgcacagacatttgtcagggt
ggtctaggtgactgctggcttctggctgccattgcctccctgaccctgaatgaagagctg
ctttaccgggtggtccccagggaccaggacttccaggagaactatgcgggaatctttcac
tttcagttctggcagtacggagagtgggtggaggtggtcattgacgacaggctgcccacc
aagaatggacagctgctcttcctacactcggaacaaggcaatgaattctggagtgccctg
ctggagaaagcctatgccaagcttaatggttgttatgaggctctcgctggaggttccaca
gtggaggggtttgaggatttcacaggtggcatctctgagttttatgacctgaagaaacca
ccagccaatctatatcagatcatccggaaggccctctgtgcggggtctctgctgggctgc
tccattgatgtctccagtgcagccgaagccgaagccatcaccagccagaagctggttaag
agtcatgcgtactctgtcactggagtcgaagaggtgaatttccagggccatccagagaag
ctgatcagactcaggaatccatggggtgaagtggagtggtcgggagcctggagcgatgat
gcaccagagtggaatcacatagacccccggcggaaggaagaactggacaagaaagttgag
gatggagaattctggatgtcactttcagatttcgtgaggcagttctctcggttggagatc
tgcaacctgtccccggactctctgagtagcgaggaggtgcacaaatggaacctggtcctg
ttcaacggccactggacccggggctccacagctgggggctgccagaactacccagccacg
tactggaccaatccccagttcaaaatccgtttggatgaagtggatgaggaccaggaggag
agcatcggtgaaccctgctgtacagtgctgctgggcctgatgcagaaaaatcgcaggtgg
cggaagcggataggacaaggcatgcttagcatcggctatgccgtctaccaggttcccaag
gagctggagagtcacacggacgcacacttgggccgggatttcttcctggcctaccagccc
tcagcccgcaccagcacctacgtcaacctgcgggaggtctctggccgggcccggctgccc
cctggggagtacctggtggtgccatccacatttgaacccttcaaagacggcgagttctgc
ttgagagtgttctcagagaagaaggcccaggccctagaaattggggatgtggtagctgga
aacccatatgagccacatcccagtgaggtggatcaggaagatgaccagttcaggaggctg
tttgagaagttggcagggaaggattctgagattactgccaatgcactcaagatacttttg
aatgaggcgttttccaagagaacagacataaaattcgatggattcaacatcaacacttgc
agggaaatgatcagtctgttggatagcaatggaacgggcactttgggggcggtggaattc
aagacgctctggctgaagattcagaagtatctggagatctattgggaaactgattataac
cactcgggcaccatcgatgcccacgagatgaggacagccctcaggaaggcaggtttcacc
ctcaacagccaggtgcagcagaccattgccctgcggtatgcgtgcagcaagcttggcatc
aactttgacagcttcgtggcttgtatgatccgcctggagaccctcttcaaactattcagc
cttctggacgaagacaaggatggcatggttcagctctctctggccgagtggctgtgctgc
gtgttggtctga
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