Homo sapiens (human): 7175
Help
Entry
7175 CDS
T01001
Symbol
TPR, MRT79
Name
(RefSeq) translocated promoter region, nuclear basket protein
KO
K09291
nucleoprotein TPR
Organism
hsa
Homo sapiens (human)
Pathway
hsa03013
Nucleocytoplasmic transport
hsa05014
Amyotrophic lateral sclerosis
hsa05200
Pathways in cancer
hsa05216
Thyroid cancer
Disease
H00032
Thyroid cancer
H00768
Autosomal recessive intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09122 Translation
03013 Nucleocytoplasmic transport
7175 (TPR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
7175 (TPR)
09162 Cancer: specific types
05216 Thyroid cancer
7175 (TPR)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
7175 (TPR)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
7175 (TPR)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA surveillance and transport factors
Transport factors
Nuclear pore complex
7175 (TPR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TPR_MLP1_2
Seryl_tRNA_N
DUF5082
DUF1192
Imm70
Motif
Other DBs
NCBI-GeneID:
7175
NCBI-ProteinID:
NP_003283
OMIM:
189940
HGNC:
12017
Ensembl:
ENSG00000047410
UniProt:
P12270
Structure
PDB
LinkDB
All DBs
Position
1:complement(186311652..186375253)
Genome browser
AA seq
2363 aa
AA seq
DB search
MAAVLQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKR
LSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEEL
EAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYRE
KRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQM
NGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKS
NELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLL
SATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRIN
KYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSS
VLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSY
RNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQ
MQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVI
ESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDF
ASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVR
AENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQ
IEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKE
IATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTS
NVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD
DKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQN
KYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKD
EVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEIL
RFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHE
ELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGM
LQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKA
EIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRR
YKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENL
QKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAA
KSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREH
QERHLEQRDEPQEPSNKVPEQQRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTPSK
VTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQSEGPVEHVPV
FGSTSGSVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQSHPQIEPANQELSSNIVEV
VQSSPVERPSTSTAVFGTVSATPSSSLPKRTREEEEDSTIEASDQVSDDTVEMPLPKKLK
SVTPVGTEEEVMAEESTDGEVETQVYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDL
GPLQSDQQTTTSSQDGQGKGDDVIVIDSDDEEEDDDENDGEHEDYEEDEEDDDDDEDDTG
MGDEGEDSNEGTGSADGNDGYEADDAEGGDGTDPGTETEESMGGGEGNHRAADSQNSGEG
NTGAAESSFSQEVSREQQPSSASERQAPRAPQSPRRPPHPLPPRLTIHAPPQELGPPVQR
IQMTRRQSVGRGLQLTPGIGGMQQHFFDDEDRTVPSTPTLVVPHRTDGFAEAIHSPQVAG
VPRFRFGPPEDMPQTSSSHSDLGQLASQGGLGMYETPLFLAHEEESGGRSVPTTPLQVAA
PVTVFTESTTSDASEHASQSVPMVTTSTGTLSTTNETATGDDGDEVFVEAESEGISSEAG
LEIDSQQEEEPVQASDESDLPSTSQDPPSSSSVDTSSSQPKPFRRVRLQTTLRQGVRGRQ
FNRQRGVSHAMGGRGGINRGNIN
NT seq
7092 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggtgttgcagcaagtcctggagcgcacggagctgaacaagctgcccaagtct
gtccagaacaaacttgaaaagttccttgctgatcagcaatccgagatcgatggcctgaag
gggcggcatgagaaatttaaggtggagagcgaacaacagtattttgaaatagaaaagagg
ttgtcccacagtcaggagagacttgtgaatgaaacccgagagtgtcaaagcttgcggctt
gagctagagaaactcaacaatcaactgaaggcactaactgagaaaaacaaagaacttgaa
attgctcaggatcgcaatattgccattcagagccaatttacaagaacaaaggaagaatta
gaagctgagaaaagagacttaattagaaccaatgagagactatctcaagaacttgaatac
ttaacagaggatgttaaacgtctgaatgaaaaacttaaagaaagcaatacaacaaagggt
gaacttcagttaaaattggatgaacttcaagcttctgatgtttctgttaagtatcgagaa
aaacgcttggagcaagaaaaggaattgctacatagtcagaatacatggctgaatacagag
ttgaaaaccaaaactgatgaacttctggctcttggaagagaaaaagggaatgagattcta
gagcttaaatgtaatcttgaaaataaaaaagaagaggtttctagactggaagaacaaatg
aatggcttaaaaacatcaaatgaacatcttcaaaagcatgtggaggatctgttgaccaaa
ttaaaagaggccaaggaacaacaggccagtatggaagagaaattccacaatgaattaaat
gcccacataaaactttctaatttgtacaagagtgccgctgatgactcagaagcaaagagc
aatgaactaacccgggcagtagaggaactacacaaacttttgaaagaagctggtgaagcc
aacaaagcaatacaagatcatcttctagaggtggagcaatccaaagatcaaatggaaaaa
gaaatgcttgagaaaatagggagattggagaaggaattagagaatgcaaatgaccttctt
tctgccacaaaacgtaaaggagccatattgtctgaagaagagcttgccgccatgtctcct
actgcagcagctgtagctaagatagtgaaacctgggatgaaactaactgagctctataat
gcttatgtggaaactcaggatcagttgcttttggagaaactagagaacaaaagaattaat
aagtacctagatgaaatagtgaaagaagtggaagccaaagcaccaattttgaaacgccag
cgtgaggaatatgaacgtgcacagaaagctgtagcaagtttatctgttaagcttgaacaa
gctatgaaggagattcagcgattgcaggaggacactgataaagccaacaagcaatcatct
gtacttgagagagataatcgaagaatggaaatacaagtaaaagatctttcacaacagatt
agagtgcttttgatggaacttgaagaagcaaggggtaaccacgtaattcgtgatgaggaa
gtaagctctgctgatataagtagttcatctgaggtaatatcacagcatctagtatcttac
agaaatattgaagagcttcaacaacaaaatcaacgtctcttagtggcccttagagagctt
ggggaaaccagagaaagagaagaacaagaaacaacttcatccaaaatcactgagcttcag
ctcaaacttgagagtgcccttactgaactagaacaactccgcaaatcacgacagcatcaa
atgcagcttgttgattccatagttcgtcagcgtgatatgtaccgtattttattgtcacaa
acaacaggagttgccattccattacatgcttcaagcttagatgatgtttctcttgcatca
actccaaaacgtccaagtacatcacagactgtttccactcctgctccagtacctgttatt
gaatcaacagaggctatagaggctaaggctgcccttaaacagttgcaggaaatttttgag
aactacaaaaaagaaaaagcagaaaatgaaaaaatacaaaatgagcagcttgagaaactt
caagaacaagttacagatttgcgatcacaaaataccaaaatttctacccagctagatttt
gcttctaaacgttatgaaatgctgcaagataatgttgaaggatatcgtcgagaaataaca
tcacttcatgagagaaatcagaaactcactgccacaactcaaaagcaagaacagattatc
aatacgatgactcaagatttgagaggagcaaatgagaagctagctgtcgcagaagtaaga
gcagaaaatttgaagaaggaaaaggaaatgcttaaattgtctgaagttcgtctttctcag
caaagagagtctttgttagctgaacaaagggggcaaaacttactgctaactaatctgcaa
acaattcagggaatactggagcgatctgaaacagaaaccaaacaaaggcttagtagccag
atagaaaaactggaacatgagatctctcatctaaagaagaagttggaaaatgaggtggaa
caaaggcatacacttactagaaatctagatgttcaacttttagatacaaagagacaactg
gatacagagacaaatcttcatcttaacacaaaagaactattaaaaaatgctcaaaaagaa
attgccacattgaaacagcacctcagtaatatggaagtccaagttgcttctcagtcttca
cagagaactggtaaaggtcagcctagcaacaaagaagatgtggatgatcttgtgagtcag
ctaagacagacagaagagcaggtgaatgacttaaaggagagactcaaaacaagtacgagc
aatgtggaacaatatcaagcaatggttactagtttagaagaatccctgaacaaggaaaaa
caggtgacagaagaagtgcgtaagaatattgaagttcgtttaaaagagtcagctgaattt
cagacacagttggaaaagaagttgatggaagtagagaaggaaaaacaagaacttcaggat
gataaaagaagagccatagagagcatggaacaacagttatctgaattgaagaaaacactt
tctagtgttcagaatgaagtacaagaagctcttcagagagcaagcacagctttaagtaat
gagcagcaagccagacgtgactgtcaggaacaagctaaaatagctgtggaagctcagaat
aagtatgagagagaattgatgctgcatgctgctgatgttgaagctctacaagctgcgaag
gagcaggtttcaaaaatggcatcagtccgtcagcatttggaagaaacaacacagaaagca
gaatcacagttgttggagtgtaaagcatcttgggaggaaagagagagaatgttaaaggat
gaagtttccaaatgtgtatgtcgctgtgaagatctggagaaacaaaacagattacttcat
gatcagatcgaaaaattaagtgacaaggtcgttgcctctgtgaaggaaggtgtacaaggt
ccactgaatgtatctctcagtgaagaaggaaaatctcaagaacaaattttggaaattctc
agatttatacgacgagaaaaagaaattgctgaaactaggtttgaggtggctcaggttgag
agtctgcgttatcgacaaagggttgaacttttagaaagagagctgcaggaactgcaagat
agtctaaatgctgaaagggagaaagtccaggtaactgcaaaaacaatggctcagcatgaa
gaactgatgaagaaaactgaaacaatgaatgtagttatggagaccaataaaatgctaaga
gaagagaaggagagactagaacaggatctacagcaaatgcaagcaaaggtgaggaaactg
gagttagatattttacccttacaagaagcaaatgctgagctgagtgagaaaagcggtatg
ttgcaggcagagaagaagctcttagaagaggatgtcaaacgttggaaagcacgtaaccag
catctagtaagtcaacagaaagatccagatacagaagaatatcggaagctcctttctgaa
aaggaagttcatactaagcgtattcaacaattgacagaagaaattggtagacttaaagct
gaaattgcaagatcaaatgcatctttgactaacaaccagaacttaattcagagtctgaag
gaagatctaaataaagtaagaactgaaaaggaaaccatccagaaggacttagatgccaaa
ataattgatatccaagaaaaagtcaaaactattactcaagttaagaaaattggacgtagg
tacaagactcaatatgaagaacttaaagcacaacaggataaggttatggagacatcggct
cagtcctctggagaccatcaggagcagcatgtttcagtccaggaaatgcaggaactcaaa
gaaacgctcaaccaagctgaaacaaaatcaaaatcacttgaaagtcaagtagagaatctg
cagaagacattatctgaaaaagagacagaagcaagaaatctccaggaacagactgtgcaa
cttcagtctgaactttcacgacttcgtcaggatcttcaagatagaaccacacaggaggag
cagctccgacaacagataactgaaaaggaagaaaaaaccagaaaggctattgtagcagca
aagtcaaaaattgcacacttagctggtgtaaaagatcagctaactaaagaaaatgaggag
cttaaacaaaggaatggagccttagatcagcagaaagatgaattggatgttcgcattact
gcgctaaagtcccaatatgaaggtcgaattagtcgcttggaaagagaactcagggagcat
caagagagacaccttgagcagagagatgagcctcaagaaccttctaataaggtccctgaa
cagcagagacagatcacattgaaaacaactccagcttctggtgaaagaggaattgccagc
acatcagacccaccaacagccaatatcaagccaactcctgttgtgtctactccaagtaaa
gtgacagctgcagctatggctggaaataagtcaacacccagggctagtatccgcccaatg
gttacacctgcaactgttacaaatcccactactaccccaacagctacagtgatgcccact
acacaagtggaatcacaggaagctatgcagtcagaagggcctgtggaacatgttccagtt
tttggaagcacaagtggatccgttcgttctactagtcctaatgtccagccttctatctct
caacctattttaactgttcagcaacaaacacaggctacagcttttgtgcaacccactcaa
cagagtcatcctcagattgagcctgccaatcaagagttatcttcaaacatagtagaggtt
gttcagagttcaccagttgagcggccttctacttccacagcagtatttggcacagtttcg
gctacccccagttcttctttgccaaagcgtacacgtgaagaggaagaggatagcaccata
gaagcatcagaccaagtctctgatgatacagtggaaatgcctcttccaaagaagttgaaa
agtgtcacacctgtaggaactgaggaagaagttatggcagaagaaagtactgatggagag
gtagagactcaggtatacaaccaggattctcaagattccattggagaaggagttacccag
ggagattatacacctatggaagacagtgaagaaacctctcagtctctacaaatagatctt
gggccacttcaatcagatcagcagacgacaacttcatcccaggatggtcaaggcaaagga
gatgatgtcattgtaattgacagtgatgatgaagaagaggatgatgatgaaaatgatgga
gaacatgaggattatgaagaggatgaggaagatgatgatgatgatgaagatgacacaggg
atgggagatgagggtgaagatagtaatgaaggaactggtagtgccgatggcaatgatggt
tatgaagctgatgatgctgagggtggtgatgggactgatccaggtacagaaacagaagaa
agtatgggtggaggtgaaggtaatcacagagctgctgattctcaaaacagtggtgaagga
aatacaggtgctgcagaatcttctttttctcaggaggtttctagagaacaacagccatca
tcagcatctgaaagacaggcccctcgagcacctcagtcaccgagacgcccaccacatcca
cttcccccaagactgaccattcatgccccacctcaggagttgggaccaccagttcagaga
attcagatgacccgaaggcagtctgtaggacgtggccttcagttgactccaggaataggt
ggcatgcaacagcatttttttgatgatgaagacagaacagttccaagtactccaactctt
gtggtgccacatcgtactgatggatttgctgaagcaattcattcgccgcaggttgctggt
gtccctagattccggtttgggccacctgaagatatgccacaaacaagttctagtcactct
gatcttggccagcttgcttctcaaggaggtttaggaatgtatgaaacacccctgttccta
gctcatgaagaagagtcaggtggccgaagtgttcccactactccactacaagtagcagcc
ccagtgactgtatttactgagagcaccacctctgatgcttcggaacatgcctctcaatct
gttccaatggtgactacatccactggcactttatctacaacaaatgaaacagcaacaggt
gatgatggagatgaagtatttgtggaggcagaatctgaaggtattagttcagaagcaggc
ctagaaattgatagccagcaggaagaagagccggttcaagcatctgatgagtcagatctc
ccctccaccagccaggatcctccttctagctcatctgtagatactagtagtagtcaacca
aagcctttcagacgagtaagacttcagacaacattgagacaaggtgtccgtggtcgtcag
tttaacagacagagaggtgtgagccatgcaatgggagggagaggaggaataaacagagga
aatattaattaa
Homo sapiens (human): 7170
Help
Entry
7170 CDS
T01001
Symbol
TPM3, CAPM1, CFTD, CMYP4A, CMYP4B, HEL-189, HEL-S-82p, NEM1, OK/SW-cl.5, TM-5, TM3, TM30, TM30nm, TM5, TPM3nu, TPMsk3, TRK, hscp30
Name
(RefSeq) tropomyosin 3
KO
K09290
tropomyosin 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04260
Cardiac muscle contraction
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04814
Motor proteins
hsa04820
Cytoskeleton in muscle cells
hsa05200
Pathways in cancer
hsa05216
Thyroid cancer
hsa05410
Hypertrophic cardiomyopathy
hsa05414
Dilated cardiomyopathy
Disease
H00032
Thyroid cancer
H00698
Nemaline myopathy
H00701
Congenital fiber type disproportion
H00702
Cap myopathy
H01810
Congenital myopathy
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09142 Cell motility
04814 Motor proteins
7170 (TPM3)
04820 Cytoskeleton in muscle cells
7170 (TPM3)
09150 Organismal Systems
09153 Circulatory system
04260 Cardiac muscle contraction
7170 (TPM3)
04261 Adrenergic signaling in cardiomyocytes
7170 (TPM3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
7170 (TPM3)
09162 Cancer: specific types
05216 Thyroid cancer
7170 (TPM3)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
7170 (TPM3)
05414 Dilated cardiomyopathy
7170 (TPM3)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
7170 (TPM3)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
Tropomyosins
7170 (TPM3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Tropomyosin
Laminin_II
CLZ
Crescentin
TMF_DNA_bd
DUF745
ATG16
Lebercilin
XhlA
DUF3450
CENP-F_leu_zip
HrpB7
Nuf2_DHR10-like
DUF1664
SlyX
Laminin_I
EzrA
DUF16
Motif
Other DBs
NCBI-GeneID:
7170
NCBI-ProteinID:
NP_689476
OMIM:
191030
HGNC:
12012
Ensembl:
ENSG00000143549
UniProt:
P06753
Structure
PDB
LinkDB
All DBs
Position
1:complement(154155308..154192100)
Genome browser
AA seq
285 aa
AA seq
DB search
MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDK
YSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA
ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERT
EERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRA
EFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI
NT seq
858 nt
NT seq
+upstream
nt +downstream
nt
atgatggaggccatcaagaaaaagatgcagatgctgaagttagacaaggagaatgctctg
gatcgggcagagcaagctgaagctgagcagaagcaggcagaagaaagaagtaaacagctg
gaggatgagctggcagccatgcagaagaagctgaaagggacagaggatgagctggacaag
tattctgaagctttgaaggatgcccaggagaagctggaactggcagagaagaaggctgct
gatgctgaggctgaggtggcctccttgaaccgtaggatccagctggttgaagaagagctg
gaccgtgctcaggagcgcctggccactgccctgcaaaagctggaagaagctgaaaaagct
gctgatgagagtgagagaggtatgaaggttattgaaaaccgggccttaaaagatgaagaa
aagatggaactccaggaaatccaactcaaagaagctaagcacattgcagaagaggcagat
aggaagtatgaagaggtggctcgtaagttggtgatcattgaaggagacttggaacgcaca
gaggaacgagctgagctggcagagtctaagtgttctgagctggaggaggagctgaagaat
gtcaccaacaacctcaagtctcttgaggctcaggcggagaagtactctcaaaaagaagat
aaatatgaggaagaaatcaagattcttactgataaactcaaggaggcagagacccgtgct
gagtttgctgagagatcggtagccaagctggaaaagacaattgatgacctggaagatgag
ctctatgcccagaaactgaagtacaaggccattagcgaggagctggaccacgccctcaat
gacatgacctctatataa
DBGET
integrated database retrieval system
