Homo sapiens (human): 8314
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Entry
8314 CDS
T01001
Symbol
BAP1, HUCEP-13, KURIS, TPDS1, UBM2, UCHL2, UVM2, hucep-6
Name
(RefSeq) BRCA1 associated protein 1
KO
K08588
ubiquitin carboxyl-terminal hydrolase BAP1 [EC:
3.4.19.12
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03083
Polycomb repressive complex
Network
nt06523
Epigenetic regulation by Polycomb complexes
Element
N01585
Deubiquitination of H2AK119
Disease
H02623
Kury-Isidor syndrome
H02624
Tumor predisposition syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09126 Chromosome
03083 Polycomb repressive complex
8314 (BAP1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
8314 (BAP1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
8314 (BAP1)
03036 Chromosome and associated proteins [BR:
hsa03036
]
8314 (BAP1)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.19 Omega peptidases
3.4.19.12 ubiquitinyl hydrolase 1
8314 (BAP1)
Peptidases and inhibitors [BR:
hsa01002
]
Cysteine peptidases
Family C12: ubiquitin C-terminal hydrolase family
8314 (BAP1)
Ubiquitin system [BR:
hsa04121
]
Deubiquitinating enzyme (DUB)
Ubiquitin-specific proteases (UBPs)
UCH
8314 (BAP1)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Histone modification proteins
Polycomb repressive complex (PRC) and associated proteins
PR-DUB complex
8314 (BAP1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_C12
UCH_C
Motif
Other DBs
NCBI-GeneID:
8314
NCBI-ProteinID:
NP_004647
OMIM:
603089
HGNC:
950
Ensembl:
ENSG00000163930
UniProt:
Q92560
Structure
PDB
LinkDB
All DBs
Position
3:complement(52401008..52410008)
Genome browser
AA seq
729 aa
AA seq
DB search
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRR
KVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSSVDLGPTLSRMKDFTK
GFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIK
YEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANR
APAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKG
KGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPT
HSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLR
VDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVE
KEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKF
KIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKR
SRPYKAKRQ
NT seq
2190 nt
NT seq
+upstream
nt +downstream
nt
atgaataagggctggctggagctggagagcgacccaggcctcttcaccctgctcgtggaa
gatttcggtgtcaagggggtgcaagtggaggagatctacgaccttcagagcaaatgtcag
ggccctgtatatggatttatcttcctgttcaaatggatcgaagagcgccggtcccggcga
aaggtctctaccttggtggatgatacgtccgtgattgatgatgatattgtgaataacatg
ttctttgcccaccagctgatacccaactcttgtgcaactcatgccttgctgagcgtgctc
ctgaactgcagcagcgtggacctgggacccaccctgagtcgcatgaaggacttcaccaag
ggtttcagccctgagagcaaaggatatgcgattggcaatgccccggagttggccaaggcc
cataatagccatgccaggcccgagccacgccacctccctgagaagcagaatggccttagt
gcagtgcggaccatggaggcgttccactttgtcagctatgtgcctatcacaggccggctc
tttgagctggatgggctgaaggtctaccccattgaccatgggccctggggggaggacgag
gagtggacagacaaggcccggcgggtcatcatggagcgtatcggcctcgccactgcaggg
gagccctaccacgacatccgcttcaacctgatggcagtggtgcccgaccgcaggatcaag
tatgaggccaggctgcatgtgctgaaggtgaaccgtcagacagtactagaggctctgcag
cagctgataagagtaacacagccagagctgattcagacccacaagtctcaagagtcacag
ctgcctgaggagtccaagtcagccagcaacaagtccccgctggtgctggaagcaaacagg
gcccctgcagcctctgagggcaaccacacagatggtgcagaggaggcggctggttcatgc
gcacaagccccatcccacagccctcccaacaaacccaagctagtggtgaagcctccaggc
agcagcctcaatggggttcaccccaaccccactcccattgtccagcggctgccggccttt
ctagacaatcacaattatgccaagtcccccatgcaggaggaagaagacctggcggcaggt
gtgggccgcagccgagttccagtccgcccaccccagcagtactcagatgatgaggatgac
tatgaggatgacgaggaggatgacgtgcagaacaccaactctgcccttaggtataagggg
aagggaacagggaagccaggggcattgagcggttctgctgatgggcaactgtcagtgctg
cagcccaacaccatcaacgtcttggctgagaagctcaaagagtcccagaaggacctctca
attcctctgtccatcaagactagcagcggggctgggagtccggctgtggcagtgcccaca
cactcgcagccctcacccacccccagcaatgagagtacagacacggcctctgagatcggc
agtgctttcaactcgccactgcgctcgcctatccgctcagccaacccgacgcggccctcc
agccctgtcacctcccacatctccaaggtgctttttggagaggatgacagcctgctgcgt
gttgactgcatacgctacaaccgtgctgtccgtgatctgggtcctgtcatcagcacaggc
ctgctgcacctggctgaggatggggtgctgagtcccctggcgctgacagagggtgggaag
ggttcctcgccctccatcagaccaatccaaggcagccaggggtccagcagcccagtggag
aaggaggtcgtggaagccacggacagcagagagaagacggggatggtgaggcctggcgag
cccttgagtggggagaaatactcacccaaggagctgctggcactgctgaagtgtgtggag
gctgagattgcaaactatgaggcgtgcctcaaggaggaggtagagaagaggaagaagttc
aagattgatgaccagagaaggacccacaactacgatgagttcatctgcacctttatctcc
atgctggctcaggaaggcatgctggccaacctagtggagcagaacatctccgtgcggcgg
cgccaaggggtcagcatcggccggctccacaagcagcggaagcctgaccggcggaaacgc
tctcgcccctacaaggccaagcgccagtga
DBGET
integrated database retrieval system
