Homo sapiens (human): 91662
Help
Entry
91662 CDS
T01001
Symbol
NLRP12, CLR19.3, FCAS2, NALP12, PAN6, PYPAF7, RNO, RNO2
Name
(RefSeq) NLR family pyrin domain containing 12
KO
K20865
NACHT, LRR and PYD domains-containing protein 12
Organism
hsa
Homo sapiens (human)
Pathway
hsa04621
NOD-like receptor signaling pathway
Network
nt06521
NLR signaling
Element
N01569
NALP12 inflammasome signaling pathway
Disease
H02159
Familial cold autoinflammatory syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
91662 (NLRP12)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04054 Pattern recognition receptors [BR:
hsa04054
]
91662 (NLRP12)
Pattern recognition receptors [BR:
hsa04054
]
Cytoplasmic pattern recognition receptors
NOD-like receptors
91662 (NLRP12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NACHT
NLRC4_HD2
PYRIN
LRR_6
NOD2_WH
FISNA
LRR_4
nSTAND3
NB-ARC
AAA_25
AAA_16
Motif
Other DBs
NCBI-GeneID:
91662
NCBI-ProteinID:
NP_653288
OMIM:
609648
HGNC:
22938
Ensembl:
ENSG00000142405
Pharos:
P59046
(Tbio)
UniProt:
P59046
Structure
PDB
PDBj
LinkDB
All DBs
Position
19:complement(53793584..53824403)
Genome browser
AA seq
1061 aa
AA seq
DB search
MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGSMEKAGPLEMAQLL
ITHFGPEEAWRLALSTFERINRKDLWERGQREDLVRDTPPGGPSSLGNQSTCLLEVSLVT
PRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTG
RGHARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGAAGIGKSMLAHKVMLDWADGKLF
QGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQELIRVPERLLFIIDGFDELK
PSFHDPQGPWCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHPRHV
EILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEG
GGLLRQTSRTTTAVYMLYLLSLMQPKPGAPRLQPPPNQRGLCSLAADGLWNQKILFEEQD
LRKHGLDGEDVSAFLNMNIFQKDINCERYYSFIHLSFQEFFAAMYYILDEGEGGAGPDQD
VTRLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQ
SDGSTLQQGSLEFFSCLYEIQEEEFIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSA
QVLHLYGATYSADGEDRARCSAGAHTLLVQLPERTVLLDAYSEHLAAALCTNPNLIELSL
YRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISSSACEDLSAALIANKNLTRMDLSGN
GVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMASVLGTNPHLVELDLTGNALE
DLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLG
VLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVVLQANHNLRELDLSFNDLGDWGLWL
LAEGLQHPACRLQKLWLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCK
RLSHPGCKLRVLWLFGMDLNKMTHSRLAALRVTKPYLDIGC
NT seq
3186 nt
NT seq
+upstream
nt +downstream
nt
atgctacgaaccgcaggcagggacggcctctgtcgcctgtccacctacttggaagaactc
gaggctgtggaactgaagaagttcaagttatacctggggaccgcgacagagctgggagaa
ggcaagatcccctggggaagcatggagaaggccggtcccctggaaatggcccagctgctc
atcacccacttcgggccagaggaggcctggaggttggctctcagcacctttgagcggata
aacaggaaggacctgtgggagagaggacagagagaggacctggtgagggataccccacct
ggtggcccgtcctcacttgggaaccagtcaacatgccttctggaagtctctcttgtcact
ccaagaaaagatccccaggaaacctacagggactatgtccgcaggaaattccggctcatg
gaagaccgcaatgcgcgcctaggggaatgtgtcaacctcagccaccggtacacccggctc
ctgctggtgaaggagcactcaaaccccatgcaggtccagcagcagcttctggacacaggc
cggggacacgcgaggaccgtgggacaccaggctagccccatcaagatagagaccctcttt
gagccagacgaggagcgccccgagccaccgcgcaccgtggtcatgcaaggcgcggcaggg
ataggcaagtccatgctggcacacaaggtgatgctggactgggcggacgggaagctcttc
caaggcagatttgattatctcttctacatcaactgcagggagatgaaccagagtgccacg
gaatgcagcatgcaagacctcatcttcagctgctggcctgagcccagcgcgcctctccag
gagctcatccgagttcccgagcgcctccttttcatcatcgacggcttcgatgagctcaag
ccttctttccacgatcctcagggaccctggtgcctctgctgggaggagaaacggcccacg
gagctgcttcttaacagcttaattcggaagaagctgctccctgagctatctttgctcatc
accacacggcccacggctttggagaagctccaccgtctgctggagcaccccaggcatgtg
gagatcctgggcttctctgaggcagaaaggaaggaatacttctacaagtatttccacaat
gcagagcaggcgggccaagtcttcaattacgtgagggacaacgagcctctcttcaccatg
tgcttcgtccccctggtgtgctgggtggtgtgtacctgcctccagcagcagctggagggt
ggggggctgttgagacagacgtccaggaccaccactgcagtgtacatgctctacctgctg
agtctgatgcaacccaagccgggggccccgcgcctccagcccccacccaaccagagaggg
ttgtgctccttggcggcagatgggctctggaatcagaaaatcctatttgaggagcaggac
ctccggaagcacggcctagacggggaagacgtctctgccttcctcaacatgaacatcttc
cagaaggacatcaactgtgagaggtactacagcttcatccacttgagtttccaggaattc
tttgcagctatgtactatatcctggacgagggggagggcggggcaggcccagaccaggac
gtgaccaggctgttgaccgagtacgcgttttctgaaaggagcttcctggcactcaccagc
cgcttcctgtttggactcctgaacgaggagaccaggagccacctggagaagagtctctgc
tggaaggtctcgccgcacatcaagatggacctgttgcagtggatccaaagcaaagctcag
agcgacggctccaccctgcagcagggctccttggagttcttcagctgcttgtacgagatc
caggaggaggagtttatccagcaggccctgagccacttccaggtgatcgtggtcagcaac
attgcctccaagatggagcacatggtctcctcgttctgtctgaagcgctgcaggagcgcc
caggtgctgcacttgtatggcgccacctacagcgcggacggggaagaccgcgcgaggtgc
tccgcaggagcgcacacgctgttggtgcagctaccagagaggaccgttctgctggacgcc
tacagtgaacatctggcagcggccctgtgcaccaatccaaacctgatagagctgtctctg
taccgaaatgccctgggcagccggggggtgaagctgctctgtcaaggactcagacacccc
aactgcaaacttcagaacctgaggctgaagaggtgccgcatctccagctcagcctgcgag
gacctctctgcagctctcatagccaataagaatttgacaaggatggatctcagtggcaac
ggcgttggattcccaggcatgatgctgctttgcgagggcctgcggcatccccagtgcagg
ctgcagatgattcagttgaggaagtgtcagctggagtccggggcttgtcaggagatggct
tctgtgctcggcaccaacccacatctggttgagttggacctgacaggaaatgcactggag
gatttgggcctgaggttactatgccagggactgaggcacccagtctgcagactacggact
ttgtggctgaagatctgccgcctcactgctgctgcctgtgacgagctggcctcaactctc
agtgtgaaccagagcctgagagagctggacctgagcctgaatgagctgggggacctcggg
gtgctgctgctgtgtgagggcctcaggcatcccacgtgcaagctccagaccctgcggttg
ggcatctgccggctgggctctgccgcctgtgagggtctttctgtggtgctccaggccaac
cacaacctccgggagctggacttgagtttcaacgacctgggagactggggcctgtggttg
ctggctgaggggctgcaacatcccgcctgcagactccagaaactgtggctggatagctgt
ggcctcacagccaaggcttgtgagaatctttacttcaccctggggatcaaccagaccttg
accgacctttacctgaccaacaacgccctaggggacacaggtgtccgactgctttgcaag
cggctgagccatcctggctgcaaactccgagtcctctggttatttgggatggacctgaat
aaaatgacccacagtaggttggcagcgcttcgagtaacaaaaccttatttggacattggc
tgctga
DBGET
integrated database retrieval system