Halorubrum salinarum: HPS36_00835
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Entry
HPS36_00835 CDS
T07841
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
hsai
Halorubrum salinarum
Pathway
hsai00290
Valine, leucine and isoleucine biosynthesis
hsai00660
C5-Branched dibasic acid metabolism
hsai01100
Metabolic pathways
hsai01110
Biosynthesis of secondary metabolites
hsai01210
2-Oxocarboxylic acid metabolism
hsai01230
Biosynthesis of amino acids
Module
hsai_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
hsai_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
hsai00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
HPS36_00835 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HPS36_00835 (leuC)
Enzymes [BR:
hsai01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
HPS36_00835 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
HPS36_00835 (leuC)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QKG91457
UniProt:
A0A7D4BNM0
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All DBs
Position
complement(155413..156873)
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AA seq
486 aa
AA seq
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MSEGTLYDKVWDRHKVTELPNGQDQLFIGLHLVHEVTSPQAFGMLRERELDVAYPDRTFA
TTDHIAPTEADKRERPLADDQAEEMLSALERNVSDSGITFFGFESGKQGITHVVAPELGL
SQPGMTVACGDSHTATHGAFGSIGVGIGTSQIRDVLATGCIAADKQKVRRVNVEGELGEG
VYAKDVILKVIQDLGVDGGVGHVYEYGGPAIEALDMEGRLAVCNMSIEGGARAGYINPDE
TTYEYLKGREYVPEGEAFEERKAYWESISSDDDAEYDDVVTVDADGLDPLVTWGINPGQV
IEISEPVPHPDDFEARTDREAAEQALDHMEIEAGQSMLGYDVDVAFLGTCTNGRLSDFEE
AAKILEGNTVDEDVRALAVPGSETVRQQCEERGIDQTFIEAGFQWRRAGCSMCLAMNDDA
LEGDEVCASSSNRNFIGRQGSKDGRTVLMSPAMVAAAAVEGEVADAREYLDDGPTGGAGG
VEEVAD
NT seq
1461 nt
NT seq
+upstream
nt +downstream
nt
atgagcgaggggacgctgtacgacaaggtgtgggaccgacacaaggtcaccgagctcccg
aacgggcaggaccagctgttcatcgggctccacctcgtccacgaggtgacgagcccgcag
gcgttcggcatgctgcgcgagcgcgagctcgacgtggcgtaccccgaccggacgttcgcg
acgacggaccacatcgcgcccaccgaggccgacaagcgcgagcgtcccctcgccgacgac
caggccgaggagatgctctccgcgctcgaacgcaacgtgagcgacagcgggatcacgttc
ttcggcttcgagtccggcaagcaggggatcacccacgtcgtcgccccggagctcgggctc
tcccagcccgggatgaccgtcgcctgcggcgacagccacaccgcgacccacggcgcgttc
ggctccatcggcgtcggcatcgggacgagccagatccgcgacgtgctcgcgaccggctgt
atcgccgcggacaaacagaaggtccgccgggtcaacgtcgagggcgaactcggcgagggc
gtctacgcgaaggacgtgatcctgaaggtgatccaggacctcggcgtcgacggcggcgtc
gggcacgtgtacgagtacggcggccccgccatcgaggcgctcgacatggagggccggctc
gcggtgtgtaacatgtccatcgagggcggcgcccgcgccggctacatcaacccggacgag
accacctacgagtacctgaagggccgcgagtacgtccccgagggcgaggcgttcgaggag
cgcaaggcgtactgggagtcgatcagctccgacgacgacgccgagtacgacgacgtggtc
acggtcgacgccgacgggctcgacccgctcgtcacctgggggatcaaccccggacaggtg
atcgagatctcggagccggtcccgcacccggacgacttcgaggcccggaccgaccgcgag
gcggccgagcaggcgctcgaccacatggagatcgaggccggccagtcgatgctcggctac
gacgtcgacgtggcgttcctcggcacctgtacaaacggccgcctctccgacttcgaggag
gccgcgaagatcttagaggggaacacggtcgacgaggacgtccgcgcgctggccgtcccc
gggtccgagaccgtccgccagcagtgcgaggagcgcggcatcgaccagacgttcatcgag
gccggcttccagtggcgccgcgccggctgttcgatgtgcctcgcgatgaacgacgacgcc
ctggagggcgacgaggtgtgcgcctcctcgtcgaaccggaacttcatcgggcggcagggg
tcgaaggacggccgcaccgtcctgatgagccccgcgatggtcgcggccgcggccgtcgag
ggcgaggtcgccgacgcgcgcgagtacctcgacgacgggccgacgggcggcgccggcggc
gtcgaggaggtggccgactga
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