Haloarcula sinaiiensis: KDQ40_08130
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Entry
KDQ40_08130 CDS
T07272
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
hsin
Haloarcula sinaiiensis
Pathway
hsin00290
Valine, leucine and isoleucine biosynthesis
hsin00660
C5-Branched dibasic acid metabolism
hsin01100
Metabolic pathways
hsin01110
Biosynthesis of secondary metabolites
hsin01210
2-Oxocarboxylic acid metabolism
hsin01230
Biosynthesis of amino acids
Module
hsin_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
hsin_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
hsin00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
KDQ40_08130 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KDQ40_08130 (leuC)
Enzymes [BR:
hsin01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
KDQ40_08130 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
KDQ40_08130 (leuC)
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Paralog
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GFIT
Motif
Pfam:
Aconitase
AcnX
DUF3944
Motif
Other DBs
NCBI-ProteinID:
QUJ70699
UniProt:
M0JV54
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Position
complement(1596426..1597847)
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AA seq
473 aa
AA seq
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MSQGTLYDKVWDQHKVTTLPNGQDQLFVGLHLIHEVTSPQAFGMLKERGLEVARPDLTHA
TVDHIVPTANQDRPYSDDAAETMMTELEENVRDAGIQFSDPTTGDQGIVHVIGPEQGITQ
PGKTIVCGDSHTSTHGAFGALAFGIGTSQIRDVLATQTIAMEKQKVRKIEVTGELDEGVE
AKDIILEIIRRLGTEGGVGYVYEYAGETIENLDMEGRMSICNMSIEGGARAGYVNPDETT
YEWLEETDYFQEHPEKFEELKPYWESIRSDEDAEYDDVVEIDAGELDPVVTWGTTPGQGI
GIDDPIPEPEDLADDKVDTARRAQKHMRVEPGETMEGYDIDVAFLGSCTNARLPDLRRAA
RIVKGREVADDVRAFVVPGSQRVQRAAEEEGLKDIFEEAGFEWRNAGCSMCLGMNEDQLE
GDEACASSSNRNFVGRQGSKDGRTVLMNPRMVAAAAITGEVSDVRDLKEVTLA
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgagtcagggaacgctgtacgacaaggtatgggaccagcacaaagtcacgaccctgccg
aacggccaagaccagctgttcgtcgggctgcacctcattcacgaggtcaccagcccgcag
gctttcggcatgctcaaagagcgtggtcttgaggtcgcacgcccggacctgacccacgcg
acggtcgaccacatcgtcccgaccgccaatcaggaccggccctacagcgacgacgcggcc
gagacgatgatgaccgaacttgaggagaacgtccgcgacgccggtatccagttctctgac
ccaacgacgggcgaccagggtatcgtccatgtcatcggcccggagcagggcatcacccag
cccggcaagaccatcgtctgtggtgacagccacacctcgacccacggcgcgttcggcgcg
ctcgcgttcggtatcgggacgagccagatccgcgacgtactggccacccagaccatcgcg
atggagaaacagaaggtccgcaaaattgaggtcaccggcgaactcgacgagggcgtcgag
gccaaggacatcattctcgaaatcatccgccggctcggaaccgagggcggcgtcggctac
gtctacgagtacgccggcgagaccatcgagaacctcgacatggagggtcggatgtctatc
tgtaatatgtccatcgagggcggcgctcgcgcgggctatgtcaaccccgacgagaccacc
tacgagtggctcgaagagacggactacttccaggaacaccccgagaaattcgaggaactc
aagccctactgggagtccatccgctccgacgaggacgccgagtacgacgacgtcgtcgaa
atcgacgcgggcgaactggaccctgtcgtcacgtggggaaccacacccggccagggcatc
ggtatcgacgacccgattccggagcccgaggatctggccgacgacaaggtcgacaccgcc
cgccgcgcccagaagcacatgcgcgtcgagcccggcgagacgatggaagggtacgacatc
gacgttgccttccttggctcctgtaccaacgctcggctgcctgatctccgccgcgcggcc
cgcatcgtcaagggccgcgaggtcgccgacgacgtgcgagcgttcgtcgtccccggcagc
cagcgcgtccagcgcgccgccgaggaagaaggcctgaaagacatcttcgaggaagccggc
ttcgagtggcgcaacgccggctgttcgatgtgtctgggcatgaacgaggaccagctggaa
ggcgacgaggcctgtgcttcctcctcgaaccggaacttcgtcggccggcagggcagcaag
gacggtcggaccgtcctgatgaacccgcggatggtggctgctgcggccatcaccggcgaa
gtgtctgacgtgcgcgacctgaaggaggtgaccctggcatga
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