Histophilus somni 2336: HSM_1012
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Entry
HSM_1012 CDS
T00673
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
hsm
Histophilus somni 2336
Pathway
hsm00010
Glycolysis / Gluconeogenesis
hsm00020
Citrate cycle (TCA cycle)
hsm00620
Pyruvate metabolism
hsm00785
Lipoic acid metabolism
hsm01100
Metabolic pathways
hsm01110
Biosynthesis of secondary metabolites
hsm01120
Microbial metabolism in diverse environments
hsm01200
Carbon metabolism
hsm01210
2-Oxocarboxylic acid metabolism
Module
hsm_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hsm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
HSM_1012
00020 Citrate cycle (TCA cycle)
HSM_1012
00620 Pyruvate metabolism
HSM_1012
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HSM_1012
Enzymes [BR:
hsm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
HSM_1012
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
ACA30723
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Position
1154509..1157172
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AA seq
887 aa
AA seq
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MSDILKNDVDPVETNDWLLAIDSVIREEGIERAQYIIEQLMQHARANSVSLPTGVSTDYI
NTIPPSEEPNYPGNLDLERRIRSAIRWNSIMMVLRASKKDLDLGGHMSSFQSSATIYEVC
FNHFFKARTEKNGGDLVFFQGHISPGIYARAFLEGRVTEEQLDNFRQEVEGKGLPSYPHP
KLMPEFWQFPTVSMGLGPLNAIYQARFLKYLHNRGLKDTSEQTVYAFLGDGEMDEVESRG
AIAFAAREKLDNLVFVINCNLQRLDGPVTGNGKIIQELEAQFNGSGWEVIKVIWGRRWDR
LLQRDTSGKLLQLMMEVVDGDYQTFKSKDGAYVRKHFFGRYPETEALVAEMTDDEIFALN
RGGHDPLKVFAAFNKAKQVKDKPVVLLVKTIKGYGMGEAAEGRNIAHQVKKMDMSGVKHV
RDRFNVPVSDAEIDNLPYVKFAEGTEEYKYLHERRQALNGYLPTRLPRFTQQMDVPALEE
FAQLFEEQSRPISTTMAFVRSLNVLLKNKSVGKHIVPIIADEARTFGMEGLFRQIGIYNP
HGQNYTPQDREQVSYYREAIDGQVLQEGINEQGATASWLAAATSYSTNDMPMIPFFVYYS
IFGFQRVGDLMWLAGDQRARGFMIGGTSGRTTLNGEGLQHEDGHSHIQSSVVPNCISYDP
AFAYEVAVIIQDGVRRMYGPEQEDVYYYITTLNETYDQPAMPKGAEEGIRKGIYKFETVT
GQGKGKVQLLGSGSILRHVREAAKLLADDFGVTSDVYSVTSFTELARDGANADRWNLLHP
KAEAKVPYIAQVMNDAPAIASTDYVKLFAEQVRPYIPAQSYRVLGTDGFGRSDSRENLRK
HFEVNAHYVVIAALTELAQQGTISKDVVAQAISKYGIDADKINPLYA
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgtcagatatattgaaaaatgacgtagatccggtcgaaaccaatgattggttattagcg
atcgattcagtaattcgtgaagaaggtattgagcgtgctcaatatattatagaacaattg
atgcaacatgcccgtgcaaattctgtgtcattaccaacgggtgtaagcacagattacatt
aacacaattcctccatcagaagagcctaattaccctggtaatttagacttggagcgtcgt
attcgtagtgcaattcgttggaattcgataatgatggtattgcgtgcttcgaaaaaagat
ttggatttaggtggacatatgtcttcttttcaatcttcagcaactatttatgaagtttgt
tttaaccatttctttaaagctcgtacagaaaaaaatggtggtgatttagtttttttccaa
ggtcatatttctccgggaatttatgcccgtgcattcttagaaggtcgtgtaacagaagag
caattagataatttccgtcaagaagttgaaggcaaggggttaccttcttatccacaccct
aaattaatgcctgaattctggcaatttccaactgtatcaatgggacttggaccattgaat
gcaatctatcaggcacgtttcttaaaatatttacataatcgtggcttgaaagacacttca
gagcaaactgtttatgcgtttttgggcgatggtgagatggatgaagtagaatctcgtggt
gcaattgcgtttgctgctcgtgagaaattagataacttagtttttgttatcaactgtaac
ttacaacgtttagacggtccggtaaccggtaacggtaaaatcattcaagaacttgaagct
caattcaatggttctggttgggaagttattaaagttatttggggacgccgttgggatcgt
ttattacaacgtgatacatcaggtaaattattacaattaatgatggaagttgttgatggc
gattatcaaactttcaaatctaaagatggtgcttatgttcgtaaacacttctttggtcgt
tatcctgaaacagaagcattagttgcggaaatgacagacgatgaaatttttgcacttaat
cgtggtggacatgatccattaaaagtgtttgcagcatttaataaagcaaaacaagttaaa
gataaaccggttgtattattggttaaaacgatcaaaggttatggcatgggagaagcagcc
gaaggtcgtaatatagctcatcaagtgaaaaaaatggatatgtcaggcgttaagcatgta
cgagatcgtttcaatgttccggtatctgatgcagaaattgataacttaccttatgttaaa
tttgcagaaggaacagaagaatataaatatcttcatgaacgtcgtcaagcattgaacggt
tatttaccgactcgtttacctcgctttacacaacaaatggatgttcctgcattagaagaa
tttgcacaattatttgaagaacaaagtcgtcctatttccactacaatggcatttgttcgt
tcattgaatgtattactgaaaaataaatctgtaggtaaacatattgttccgattattgct
gatgaagcccgcacttttggtatggaaggtttgttccgtcaaatcggtatttataaccca
catggacaaaattatactccgcaagatcgtgaacaggtatcttactatcgtgaagcaatt
gatggacaagtattgcaagaaggtatcaatgaacaaggtgcaacagcatcttggttggct
gcagcaacgtcatattcaacaaatgatatgccaatgattccattctttgtgtattattct
atttttggtttccaacgtgtaggtgatttaatgtggttagcaggcgatcaacgtgctcgt
gggttcatgattggtggtacttcgggacgtacaaccttaaatggtgagggattacaacat
gaagatggtcatagccatattcaatcttctgttgttccaaattgtatttcttatgatccg
gcttttgcttacgaagttgctgttattatacaagatggcgtgcgtcgtatgtatgggcct
gaacaagaagatgtgtattactatatcaccacactgaatgaaacttatgatcaacctgca
atgcctaaaggtgcagaagaaggtattcgtaaaggtatctataaatttgaaacagtaact
ggtcaaggcaaaggtaaggttcagttattaggttcagggtcaattttacgtcatgttcgt
gaagcggctaaattacttgctgacgatttcggcgttacatctgatgtgtacagtgttact
tcatttactgaacttgctcgtgatggtgcgaatgcggatcgttggaacttattacatcca
aaagcagaagctaaagtaccttatattgctcaagtaatgaatgatgctccggcaattgct
tcaacagattatgttaaactatttgcagaacaggttcgtccatatatacctgcacaaagt
tatcgtgtattaggtactgatggttttggtcgttcagatagtcgtgaaaatttacgtaaa
catttcgaagtaaatgcacattatgttgttattgctgcgttaaccgagttggcacagcag
ggtactatcagcaaagatgtagttgctcaagcaattagtaaatatggtattgatgcagat
aaaatcaatcctttatatgcataa
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