Halanaeroarchaeum sulfurireducens HSR2: HLASF_0249
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Entry
HLASF_0249 CDS
T03927
Symbol
leuC1
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
hsu
Halanaeroarchaeum sulfurireducens HSR2
Pathway
hsu00290
Valine, leucine and isoleucine biosynthesis
hsu00660
C5-Branched dibasic acid metabolism
hsu01100
Metabolic pathways
hsu01110
Biosynthesis of secondary metabolites
hsu01210
2-Oxocarboxylic acid metabolism
hsu01230
Biosynthesis of amino acids
Module
hsu_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
hsu_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
hsu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
HLASF_0249 (leuC1)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HLASF_0249 (leuC1)
Enzymes [BR:
hsu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
HLASF_0249 (leuC1)
4.2.1.35 (R)-2-methylmalate dehydratase
HLASF_0249 (leuC1)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
AKH96758
UniProt:
A0A0F7PBP2
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Position
236781..238049
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AA seq
422 aa
AA seq
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MGQTMTQKILSEHAGQDVTPGDTVTVDVDKALLQDGTGPLTVRQLRDMDMEQTAIPEGTV
VFLDHQAPPMNADMANEHDLLRDFVKNTGAQLSDVGDGICHQVMTFDYTAPRDILIGADS
HTVTGGAVGALATGMGSTDVGVGFATGQTWMRVPDTDEVRLEGELGEGVYAKDLILQIIG
DRGADGANYRSMEFVGPLVDDLRIDERMTISNMVVEAGAKSGIFPSDETTKEFYEDRGRA
DEWEAIEPDEDAEYQMELTYDVSELEPQVAYPHQVDNVVPVSDDRVQDVPIDQAFLGSCT
NGRLEDLRIAADILEASGMEINDDTRLIVNPASREIYEQAMEEGVFEVLNEAGAAINTPG
CGICYGGHQGALADGENAIGANNRNFKGRFGNPESDVYLGSPATVAASAIKGEITDPREV
LP
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atgggacagacaatgacccagaagattttgagtgagcacgcaggccaagacgtaacaccg
ggcgataccgtcacggtggacgtcgacaaggcgctgctgcaggatggtacgggcccgctg
acggtccgccagctgcgagacatggacatggaacagaccgccattccggagggaaccgtg
gtcttcctcgaccaccaggctccgccgatgaacgcggatatggcgaacgaacacgacctg
cttcgtgacttcgtgaagaacaccggcgcccagcttagcgatgtgggcgacggtatttgt
caccaggtcatgacgttcgattacaccgcgccgcgcgacatcctcatcggcgcggactcc
cacaccgtgaccggcggggccgtcggtgccctcgccacgggcatggggagtacggacgtc
ggcgtcgggtttgccaccgggcagacctggatgcgcgtccccgacaccgacgaggtgcgc
ctcgagggcgaactcggagagggtgtctacgccaaggacctcattctccagatcatcgga
gatcgcggtgccgacggcgcgaactatcggtcgatggagttcgtcggccccctggtcgac
gacctccgcatcgacgagcggatgaccatctcgaacatggtggtcgaggccggcgcgaag
tccggcatcttcccctcggacgagacgaccaaggagttctacgaggatcgcggccgtgcc
gacgagtgggaagcgatcgaacccgacgaggacgccgagtaccagatggagttgacgtac
gacgtcagcgagctggaaccccaggtcgcctacccccaccaggtggacaacgtggtcccg
gtctccgacgaccgcgtccaggacgtcccgatcgaccaggccttcctcggctcctgtacg
aacggtcgactcgaggaccttcggatcgccgccgacattctcgaagcttcgggcatggag
atcaacgacgacacgcgcctcatcgtgaaccccgcctcgcgcgagatctacgagcaggcg
atggaagagggcgtcttcgaagtcctcaacgaggctggcgccgccatcaacacgcctggc
tgtggcatctgttacggtggccaccagggcgcactcgccgacggcgagaacgcgatcggc
gcgaacaatcgcaacttcaagggtcgcttcgggaaccccgagtccgacgtctacctcggg
agtcccgccacggtcgccgccagtgcgatcaagggtgaaatcaccgatccccgggaggtg
ctcccctaa
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