Hymenobacter tibetensis: MTX78_22175
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Entry
MTX78_22175 CDS
T08236
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
htb
Hymenobacter tibetensis
Pathway
htb00260
Glycine, serine and threonine metabolism
htb00261
Monobactam biosynthesis
htb00270
Cysteine and methionine metabolism
htb00300
Lysine biosynthesis
htb01100
Metabolic pathways
htb01110
Biosynthesis of secondary metabolites
htb01120
Microbial metabolism in diverse environments
htb01230
Biosynthesis of amino acids
Module
htb_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
htb_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
htb00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
MTX78_22175 (thrA)
00270 Cysteine and methionine metabolism
MTX78_22175 (thrA)
00300 Lysine biosynthesis
MTX78_22175 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
MTX78_22175 (thrA)
Enzymes [BR:
htb01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
MTX78_22175 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
MTX78_22175 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
ACT_7
NAD_binding_3
ACT
Motif
Other DBs
NCBI-ProteinID:
UOG74808
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All DBs
Position
5488529..5490973
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AA seq
814 aa
AA seq
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MQVLKFGGSSVATAPNLQRVAQLVEAAAQQTPTVVVVSALGGTTDALIEAGRLAAAGSDE
YRSRLTRLEERHLEAVRGLLPIPDQSAVLSLVKTYCNELDSLCDGIFSLGELSNRTLDRL
VSFGELLSSRLLAACLKAHGVPHVWHDSRTLIRTNSQHGFAAVDTAVTNQQIQDFVLEHP
SSVYVVPGFIGSDAQGITTTLGRGGSDYTAAIFAGALTANQLEIWTDVSGMMTADPRLVT
LARPIPRISYQEAMELSHFGAKVLYPPTIQPVMSQGIPLWIKNTFAPEDEGTLVEVSPPA
NRDVVRGLSSISHLALLNLEGSGMVGIPGFSRRLFGALAVLRINVILITQSSSEHSICVA
VQAADAGAAQAAVDEEFSTEIAAGKVAPLRCEMDLAIVALVGEQMRNHPGISGRMFGALG
QNGVNIRAIAQGSSERNISVVIRAADVRKAINVLHEEFFEETTKQVNLFVAGVGNVGRKL
LEQMARQQQWLREKLRLNLRVVGLANSQRFVLSEDGIELNDWQIALEQGQQLNLSELVEQ
LNARNLRNTVFVDVTASADVAKIYAALLEKSVAVVACNKVACSSEYVNYARLKSLAREFN
AEFLFETNVGAGLPVIGSLNDLLRSGDQVHRIEAVLSGTLNFVFNHYDGTVPFADVVRQA
QAEGYTEPDPRLDLSGTDVARKILILAREAGQEMELADIHNESFLPASCLEGDVEAFYEQ
LAVHEAHFRSLFDAAAAQGQRLKFVARYADGQASVGLQGVAPGHDFYVLQGKDNAVLFFT
NRYPEQPLVVKGAGAGADVTASGVFADVIRAARA
NT seq
2445 nt
NT seq
+upstream
nt +downstream
nt
atgcaggttctgaaatttggtggttcttcggtggctacggcacccaatctccagcgtgtg
gcgcagctcgtggaagcggctgcccaacaaacgcccacagtggtagtagtgtcggcgctg
ggcggcaccaccgatgcgctgattgaagccggccgcctcgccgccgctggctccgatgag
taccgctctcggctcacccgcttggaagagcgccatctagaagccgtgcgcggcctgctc
cctattcccgaccaaagcgccgtgctgagtttggtgaaaacgtattgcaacgagctggac
agcttgtgtgacggtatattttcactgggtgagctctcgaaccgaacgttggaccggctg
gtcagctttggggagttgctttcgtcgcggctactggccgcctgcttgaaagcccacggc
gtaccccacgtctggcatgacagccgcacgctgattcgcaccaactcgcagcacggcttt
gcagccgtagacacggccgttaccaaccagcagattcaggactttgtgttggagcatcca
agttcggtgtatgtggtgccgggctttattggcagtgatgcgcaaggcatcaccactacc
ctgggccgcggcggctccgactacacggcggccatcttcgcgggtgccttgacggccaat
caattggaaatctggacggatgtgagcggtatgatgacggctgatccgcgtctcgtgacg
ctggctcgcccgattccgcgcatctcgtatcaagaggcgatggaactgtcgcactttgga
gccaaggtattgtatccgcctactattcagccagtcatgagccagggcattccgctttgg
atcaaaaacacctttgcgcccgaagacgaaggcacgcttgtagaagtaagtccgccagcc
aatcgggacgtagtacgggggctgtccagtatctcgcacctggccttgctgaacctggaa
ggcagcggcatggtgggcataccggggttttcgcggcggctgttcggcgctttagcggtg
ttgcgcatcaacgttattcttatcacccaaagctcttccgagcactctatctgcgtggct
gtgcaagctgccgacgcgggcgcagcgcaagccgccgtggatgaagagttcagcacggaa
atagcggccggtaaagtggcaccgctacgctgcgaaatggatttggccattgtggccctg
gtgggcgaacagatgcgcaaccacccaggcatcagcggacggatgtttggagcgcttggc
cagaacggtgtcaacatccgggctattgcgcagggctcatcggagcgcaacatatcggtg
gtgatacgggcggcggatgtgcgcaaagccatcaacgtgcttcatgaggagtttttcgag
gagaccaccaagcaagtgaacctgtttgtggccggcgtgggcaacgtgggccggaaacta
cttgaacaaatggcgcggcagcagcagtggttacgcgagaagctacgtctcaacttgcgg
gtagtagggctggccaacagccagcggtttgtgctaagtgaagacggtatcgagctaaac
gactggcaaatcgccttagagcaggggcagcaactgaatttgagtgagttagtggagcaa
ctgaatgcccgcaacctgcgcaacactgtgtttgtggacgtaacggccagcgccgacgta
gctaaaatctatgcggccctgctggaaaaaagtgtggcggtggtggcctgcaacaaggta
gcttgctcctcagagtacgtaaactacgctcgtttgaagtctttggctcgagagttcaac
gctgagtttctgtttgaaaccaacgtaggcgccggcctgcccgttatcggctcgctcaac
gatttgctgcgcagtggcgaccaggtacaccgcatcgaggcggtgctgtcgggcacgctc
aacttcgtgttcaaccactacgatggcactgttcctttcgccgatgtagtgcggcaggcg
caagccgaaggctacaccgagccagacccacgcctcgacttgagcggcaccgacgtagcc
cgcaaaatcctgattttggcccgcgaagccggtcaggaaatggaactggctgatattcac
aacgaatctttcctaccggcctcctgcctggaaggcgatgtggaagctttctatgaacaa
ctggcggtgcacgaagcccacttccgcagcctctttgatgccgcggctgcccaaggccaa
cgcctgaagttcgtggcgcggtatgctgatgggcaagccagcgtggggctgcaaggcgtg
gcgccgggccacgacttttatgtgctgcaaggcaaggacaacgcggtgctgttcttcacc
aaccgctaccccgagcagcccttggtagtgaaaggagccggcgcaggggctgatgttacg
gcctccggtgtttttgccgatgtcatccgggcggcacgggcatag
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