Halorhabdus tiamatea: HTIA_0349
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Entry
HTIA_0349 CDS
T02781
Name
(GenBank) dihydrofolate synthase / folylpoly glutamate synthase / alternative dihydrofolate reductase 2 / dihydropteroate synthase
KO
K24102
dihydrofolate synthase / dihydropteroate synthase [EC:
6.3.2.12
2.5.1.15
]
Organism
hti
Halorhabdus tiamatea
Pathway
hti00790
Folate biosynthesis
hti01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
hti00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HTIA_0349
Enzymes [BR:
hti01000
]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.15 dihydropteroate synthase
HTIA_0349
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HTIA_0349
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Gene cluster
GFIT
Motif
Pfam:
Pterin_bind
Mur_ligase_M
Mur_ligase_C
CoA_binding_2
Motif
Other DBs
NCBI-ProteinID:
CCQ32497
UniProt:
F7PH80
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All DBs
Position
344474..346915
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AA seq
813 aa
AA seq
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MHYHDAANFLFDLRRFDPRPGTEATRELLAALGDPHESLTAVQIAGSNGKGSTARMLEAV
LREAGLDVGLYTSPHLDDVRERVRVNGRKISKAALVEFVEEVEPYATEKAAAGDSPTFFE
TLTAMAFWEFDRQDVDIAILEVGIGGRYDATSVVDPVASAVTSVTLEHTDLLGDTVAEIA
RDKAAVAPADAPLVTATTGDALAAIHDEVGAVVRVGDPDEDADLTVEHGGRDGIESSVTL
SGQGLDVETRLPLLGEHQARNAGVAAALARQVGDVSEETLAAGLRRGHWPGRFEVLDREP
LVVLDGAHNPGGCARVAETLETFEYDDLHLVVGAMCDKDHHGIAAALPEADHVTATHPDV
DRAEDEQVVAHAFEAETDADIRTRSDVAGALADALEAADPDDAVLVSGSLYAVREARTRW
TRPNVPKRVESIPDAEGVLETAHVTEAGTWRMRGKGVHRVLKTRVQPRQAQYLKEELLSL
GGECAVSGLGDQDREHVDAVMMGTLAQFKRLAGKLDGQPYGLSPFADEIREALEIGVAPD
ERGYPWEDGTAVMGILNVTPDSFHDGGEHNAVEEAIGRAEEMIEAGVDIVDVGGESTRPG
ADPVPVEEERNRVIPVIERLASEDVTISIDTRKVPVAEAALEAGADILNDVTGLDDPAMA
HLAAEHDVPIVVMHSIDTPVDPDHDVHYDDVVEDVIEELTERVLLAEKAGLDRSQILVDP
GLGFGKTDAENFEVLDRLGEFEALGCPLLVGHSHKSMFGLIDRDADERYEPTIAATALAA
ERGADVIRVHDVAANVAAVDVVEAADDPGSFEE
NT seq
2442 nt
NT seq
+upstream
nt +downstream
nt
atgcactatcacgacgccgcgaactttctcttcgatctgcggcggttcgaccctcgaccg
gggaccgaagccacccgtgagttgctggccgcactcggcgatcctcacgagtcgctgacg
gccgtccagatcgccggctcgaacggcaaaggttcgaccgcgcgaatgctcgaagccgtg
ctcagagaggctggcctcgacgtggggctgtacacctcgccccatctcgacgacgtccgc
gagcgcgtccgggtcaacggacgcaagatttcgaaggcggcgctcgtcgaattcgtcgag
gaagtcgagccctacgccaccgagaaggccgccgccggcgactcgccgacgttcttcgag
acgctgactgccatggcgttctgggagttcgaccgccaggacgtcgatatcgccatcctc
gaagtgggcatcggcggccgctacgacgcgacgagcgtcgtcgatccggtcgcgagcgcg
gtcacgagcgtgacgctcgaacacaccgatctcctcggcgatactgtcgccgagatcgcc
cgtgacaaggccgccgtcgcccccgcggacgccccgctcgtgacggcgacgaccggcgac
gcgctggctgccatccacgacgaagtcggggccgtcgttcgtgtcggtgacccggacgag
gacgctgacctcacagtcgaacacgggggacgcgacgggatcgagagctcggtcacgctg
tccggacaggggttggacgtcgagacgcgactcccgctgctgggcgagcatcaggcacgc
aacgccggggtcgccgccgcgctcgctcgacaggtcggcgacgtcagcgaggagacgctc
gctgccggcctccgtcgcggccactggcccggtcgattcgaggtgctcgatcgcgagccg
ctggtcgtcctcgacggggcacacaaccccggcggctgtgcgcgggtcgccgagacgctg
gaaacgttcgagtacgacgatctccacctggtcgtcggcgcgatgtgtgacaaggaccac
cacggcatcgccgccgcgctgccggaagccgatcacgtcaccgccacccatcccgacgtc
gaccgcgccgaggacgagcaggtcgtcgcccacgccttcgaggccgagacggacgcggac
attcggacgcgctcggacgtcgccggcgcgctcgccgatgcgctcgaggcggccgacccg
gacgacgccgtactcgtctcggggtcgctgtacgccgtccgggaggcccggacgcgctgg
acgcggccgaacgttcccaagcgcgtcgagtcgatccccgacgccgagggggtcctcgaa
acggcccacgtcaccgaggccggcacctggcggatgcgtggcaagggcgtccaccgcgtg
ctcaagacccgcgtccagcccagacaggcccagtatctcaaagaggagctgctctcgctc
ggcggggagtgtgccgtctccggcctcggggatcaggaccgcgagcacgtcgacgccgtc
atgatgggcacgctcgcacagttcaagcgcctcgccgggaaactcgacggccagccctac
ggcctctcgcccttcgccgacgagatcagggaggccctcgaaatcggcgtcgcgcctgac
gagcggggctacccctgggaggacggcaccgcagtcatgggcattctgaacgtcacgccc
gacagcttccacgacggcggcgagcacaatgccgtcgaggaggcgatcgggcgcgccgag
gaaatgatcgaagccggcgtcgacatcgtcgacgtcggcggcgagagcacccgccccggg
gccgatccggtccccgtcgaggaggaacgcaatcgagtgattcccgtgatcgagcgcctc
gcaagcgaggacgtgactatctcgatcgacacgcggaaggttcccgtcgccgaggctgcc
ctggaagccggcgcggacatcctcaacgacgtcaccggcctcgacgacccggcgatggca
cacctcgccgccgagcacgacgtccccatcgtcgtcatgcactcgatcgacacgccggtc
gatccagaccacgacgtccactacgacgacgtcgtcgaggacgtcatcgaggaattgacc
gagcgcgtcctgctcgccgagaaggccggtctggatcgctctcagattctcgtcgatccc
ggcctgggcttcgggaaaaccgacgccgagaacttcgaagttctggatcgcctgggggag
ttcgaggcactcggctgtccgctgctggtcggccactcacacaagtcgatgttcgggctg
atcgatcgagatgctgacgaacgatacgagccgacaatcgccgcgacggcgctggcggcc
gagcgcggcgcagacgtgatccgggtccacgacgtggccgcgaacgtcgcggcggtcgat
gtcgtcgaggcagccgacgatccgggttcgttcgaagagtga
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