Hymenobacter volaticus: MUN86_22375
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Entry
MUN86_22375 CDS
T09412
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
hvl
Hymenobacter volaticus
Pathway
hvl00260
Glycine, serine and threonine metabolism
hvl00261
Monobactam biosynthesis
hvl00270
Cysteine and methionine metabolism
hvl00300
Lysine biosynthesis
hvl01100
Metabolic pathways
hvl01110
Biosynthesis of secondary metabolites
hvl01120
Microbial metabolism in diverse environments
hvl01230
Biosynthesis of amino acids
Module
hvl_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
hvl_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
hvl_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
hvl00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
MUN86_22375 (thrA)
00270 Cysteine and methionine metabolism
MUN86_22375 (thrA)
00300 Lysine biosynthesis
MUN86_22375 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
MUN86_22375 (thrA)
Enzymes [BR:
hvl01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
MUN86_22375 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
MUN86_22375 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
UOQ66206
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All DBs
Position
5117076..5119523
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AA seq
815 aa
AA seq
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MQVLKFGGSSVATAPNLQRVAQLVETAARQAPTVVVVSALGGTTDALIEAGRLAATGSDE
YRARLKYLEERHLEAVRGLLPIPDQSAVLSLVKTYCNELDSVCDGIYSLGELSNRTLDRL
VSFGELLSSRLLAACLKAHGVAHIWQDSRQLIRTNSHYGFAAVDTAVTNQQIQEFVAAQP
SSVYVVPGFIGSDAQGTTTTLGRGGSDYTAAIFAGALAAERLEIWTDVSGMMTADPRLVT
LARPIPRISYQEAMELSHFGAKVLYPPTIQPVMSQGIPLWIKNTFAPEDEGTLVEINPPA
NRDVVRGLSSIGQLALLNLEGSGMVGIPGFSRRLFGALALLRINVILITQSSSEHSICVA
VRAADAGSAQAAVDEEFSVEIAAGKVAPLRCEMDLAIVALVGEQMRNHPGISGRMFGALG
QNGVNIRAIAQGSSERNISAVIRTADVRKAINVLHEEFFEETTKQVNIFVAGVGNVGKKL
LEQMARQQQWLREKLRLNLRVVGLANSQRFVLTEDGGIELNDWQTALEQGQPLNLTELVE
QLHARNLRNTVFVDVTASADVAKTYASLLEKSMAVVACNKVACSSEYVNYARLKSLAREF
NAEFLFETNVGAGLPVIGSLNDLLRSGDEVHRIEAVLSGTLNFVFNHYDGTVPFADVVRQ
AQAEGYTEPDPRLDLSGTDVARKILILAREAGQEMELSDIHNESFLPASCLEGDVEAFYK
QLAVHESHFRSLYDAAAAQGQRLKFVARYANGKASVGLQGVAPGHDFYVLQGKDNAVLFF
TNRYPEQPLVVKGAGAGADVTASGVFADVIRAARA
NT seq
2448 nt
NT seq
+upstream
nt +downstream
nt
atgcaggttctgaaattcggtggttcgtcggtggctacggcccccaacctccaacgtgtg
gcgcagctcgtggaaacggctgcccggcaagctcccaccgtggtagtggtatcggccctc
gggggcaccaccgacgcgctgattgaagccggccgcctagctgccaccggttccgacgaa
taccgcgcccgactcaagtacttggaagagcgccatttagaagccgtgcgcggcttgctt
cccattcccgatcaaagcgccgtgttgagcttggtgaaaacctactgcaacgagctagac
agtgtgtgcgacgggatatattcgttgggtgagttgtcgaaccggacgctagaccggctg
gtgagcttcggggaattgctgtcgtcgcggctgctggcggcttgcttgaaagcacacggc
gtggcccacatttggcaagacagccggcaactgatccgcaccaactcgcattacggcttt
gcggcggtggatacggccgttaccaatcagcagattcaggagtttgtggccgcgcagcca
agttcggtgtacgtggtgccgggctttatcgggagcgatgcgcaaggcactaccaccacc
ctcggccgcggtggctccgactatacggcggccatcttcgcgggagctttggcggcggag
cggttggaaatctggaccgatgtaagcgggatgatgaccgccgaccctcgtctcgtgacg
ctggcccgcccgattccgcgcatctcgtatcaagaagccatggagttgtcgcacttcggg
gccaaggtgctgtatccgcctactattcagccggtcatgagtcagggaatcccactctgg
atcaagaataccttcgcgccggaagatgaaggtacactagtagaaataaatccgccggcc
aaccgcgacgtggtgcggggcctttcgagcatcgggcagctagcgttgctaaacctggaa
ggcagcggcatggtaggcattccgggcttctcgcggcggttgtttggggcgctggcactg
ttgcgcatcaacgtaattctcatcacccaaagctcgtcggagcactcgatctgcgtggcc
gtgcgggccgccgatgctggctcggcgcaagccgccgttgacgaggaattcagtgttgaa
atagccgccggcaaagtagcgccactgcgttgtgagatggacctagctattgtggcattg
gtgggtgagcagatgcgcaaccacccgggcatcagtgggcgaatgtttggggcgctcggc
cagaacggcgtgaacatccgggccattgcgcagggctcgtcggagcgaaatatatccgcc
gtgattcggaccgccgacgtgcgcaaggccatcaacgtgctgcacgaggagttcttcgag
gagaccaccaagcaggtgaacatctttgtagcgggagtgggcaacgtgggcaagaaactg
ctcgaacaaatggctcggcaacagcagtggctgcgcgaaaagctgcgccttaatttgcgc
gtagtgggcctagccaacagccaacgcttcgtactgacagaagacggtggcatcgagctg
aacgactggcaaacggcgctagagcaaggacaaccgctgaatttaacggaattggtcgag
cagctgcacgctcgcaatctacgcaacacggtgtttgtggacgtgacggccagcgccgac
gtagcaaaaacctatgcctcgttgctcgagaaaagtatggccgtggtagcctgcaacaag
gtggcctgctcgtcggaatacgtgaattatgcccgcttgaaatcattggcacgcgagttc
aatgccgaatttctgtttgaaaccaacgtgggggccggcctacccgtcatcggttcgctc
aacgacctattgcgcagcggcgacgaggtacaccgcattgaggccgtactctcgggcacg
ctcaattttgtgttcaaccactacgatggcaccgtgcccttcgccgacgtggtgcgccaa
gcccaagccgaaggctacaccgaacccgatccacgcctggacttgagtggcaccgacgta
gcccgcaaaatcctaattttggcgcgggaagctggtcaggaaatggagctaagtgacatt
cacaacgaatccttcctgcccgcctcttgtctggaaggcgacgtggaagctttctacaag
caattggccgtgcacgaatcccacttccgcagcctctatgatgcggccgccgctcaaggt
caacgcctcaaattcgtggcgcgctacgccaacggcaaagctagcgtcgggctgcaaggc
gtagcaccaggtcatgatttctacgtgttgcagggcaaagacaatgctgtgctcttcttc
accaaccgctaccccgagcaacctttagtagtgaaaggtgcgggcgccggcgccgatgtc
acggcctccggtgttttcgccgatgtaatccgtgccgctcgggcgtaa
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