Kluyveromyces marxianus: KLMA_10126
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Entry
KLMA_10126 CDS
T05269
Symbol
FOL1
Name
(RefSeq) folic acid synthesis protein FOL1
KO
K13939
dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:
4.1.2.25
2.7.6.3
2.5.1.15
]
Organism
kmx
Kluyveromyces marxianus
Pathway
kmx00790
Folate biosynthesis
kmx01100
Metabolic pathways
kmx01240
Biosynthesis of cofactors
Module
kmx_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
kmx00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
KLMA_10126 (FOL1)
Enzymes [BR:
kmx01000
]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.15 dihydropteroate synthase
KLMA_10126 (FOL1)
2.7 Transferring phosphorus-containing groups
2.7.6 Diphosphotransferases
2.7.6.3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
KLMA_10126 (FOL1)
4. Lyases
4.1 Carbon-carbon lyases
4.1.2 Aldehyde-lyases
4.1.2.25 dihydroneopterin aldolase
KLMA_10126 (FOL1)
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Gene cluster
GFIT
Motif
Pfam:
Pterin_bind
HPPK
FolB
Motif
Other DBs
NCBI-GeneID:
34713808
NCBI-ProteinID:
XP_022673663
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Position
1:263781..266174
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AA seq
797 aa
AA seq
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MAKQGVIPVAKRWKFHDHVHIEKLKVKAVVGPDSWDQLKPQNLNISLHMATDFSKSSRLD
DLKYSLNYAVISKDIGDYIKKNSKRNFKDLVSIGKTIVDYTKKTYPGIIDLKVEVQSKEG
NIRSNDIRGIVHSSDEETNEVLIADFKMLTLIGVFTFERMKRQFVDFTIRLPVEDGSDVP
PYNTIISQITDYVEKSNFKTVEALVETVSQVILTQNEYFIERPKLPISVKVIKLNAISET
DGVGVSCSHCYDDFRSSGPVVMEQAEKNETLTNFDLPVNTFSLDKDSWKSAVLAFGSNVG
DRFKNIVDAMNLLNAHEQVKIISTSSLFESNPMYFKDQTSFLNGCVKIKTRLLPDELLKL
CKKIEYDELRRIKHFDNGPRTIDLDIVIYYDSTGQDVTVNTEVLTIPHPRLIERSFVLEP
LCELVSPTQIHPITAETFHDHLNQLYQNENSEDLLWKVVPTGDKFLKFRTEWQRDLLTDV
RVPVSKSNGYLMGIVNVTPDSFSDGSAEYDNLSAVMSRIDTMVSEALELHDMIILDIGGC
STRPGSIQASEEEELSRTIPIIDAVTTSKTLPLDKIVLSIDTYRSAVAEAAILAGVGIIN
DISGGTFDPKILQVVGKYPNVAYVLSHIRGTIESMSTQTSYLTTDDSVDEFILDKKSDSD
KDEILFIRTIGREVCSKFEELFKNNIFRWQLFLDPGIGFAKVGKQNLDIIKHLQLLKNYS
CIKQNEYYSLVNLPVLLGPSRKKFIGDITNIPVAKDRDFVTGAILSSALANGCDIVRVHD
VRNNSKVLKLANELYRD
NT seq
2394 nt
NT seq
+upstream
nt +downstream
nt
atggcaaaacaaggtgttattccggttgctaagcgatggaaatttcatgaccatgttcat
attgagaaacttaaggtcaaggcggttgttggacctgattcatgggaccaattgaaacct
caaaatctgaatatctcattgcatatggctactgatttcagtaagtcatcacgcttggac
gatctaaaatattcacttaactatgctgttatctccaaggatataggtgactacatcaag
aaaaatagtaaaaggaattttaaggacttggtttcaattggaaagactattgtagattac
actaagaaaacctaccctggaatcattgacctgaaagttgaagttcaatctaaagaagga
aacatcagatcaaacgacatccggggcattgtgcatagttctgatgaagaaacgaatgaa
gtactaatagcagatttcaaaatgttgacattgattggtgtatttactttcgagcgtatg
aaaagacagtttgttgattttacaattcgtttacctgtggaagatggttcagatgtaccg
ccttataatacaattatatcacagatcactgattatgttgaaaaatcaaacttcaagact
gtagaagccttggttgaaacagtatctcaggtcattctaacgcaaaacgaatacttcata
gagaggccgaagttgccgataagtgtcaaggttataaagttgaacgccatcagcgaaact
gatggggttggagtttcatgttcacactgttatgatgattttagatcttcagggcccgtg
gtaatggaacaagcggagaagaatgaaacattaacaaattttgacctccctgttaatacg
ttttccttggataaagattcttggaaatcagcagttttggcttttggttcaaatgttggt
gatagatttaaaaatattgttgatgctatgaatctcttaaatgcacatgaacaggtcaaa
attatttccacctcttctttattcgaaagtaacccaatgtatttcaaagatcagacatct
tttcttaatggatgtgttaagattaagaccaggttattgccagatgagttacttaaactt
tgtaaaaaaattgaatatgatgagttaaggagaataaaacattttgataatggacctcga
acgattgatttggatattgttatttattatgactcgacagggcaagatgttactgttaat
actgaagttctaactattcctcaccctagattgattgaaagaagctttgttcttgaacca
ctatgtgaattagtaagcccaactcagatacatccgattacagccgaaacattccatgac
catttgaatcaattatatcaaaatgaaaattctgaagatctgctctggaaggttgtacct
acgggtgataaattcctaaagtttcgaactgaatggcaacgtgatttgttgacagatgta
agggtaccggtttctaaatcaaacggctatttaatggggattgtaaatgttactccagat
tcattttctgatggttctgcagagtatgataatctcagtgcggttatgagtaggattgac
accatggtgtctgaagctctggaattacacgatatgattattcttgacatcggcggttgc
tcaacaaggccagggtctatccaagcttctgaagaagaagaactatcgaggacaattccc
attatagatgcagttaccacctctaaaacattacctttagataagattgttttgtcaatt
gatacatatcgctctgctgtagcagaggctgctatacttgccggtgttggcattatcaat
gatatttcgggtggaacttttgatcctaaaattctccaggttgtgggtaagtatcctaat
gttgcttatgttttgtcccatattagaggcaccatagaatctatgtccacccaaacctca
tacttaactacagatgattccgtagatgaattcatattggataagaagagtgacagcgac
aaagatgaaatcttgtttattaggactattggtagagaggtatgttcaaaattcgaggag
ttattcaagaacaacattttccgttggcaacttttccttgatccagggattggctttgct
aaagttggaaagcaaaacttggatattatcaagcaccttcagctcttgaaaaactactct
tgtattaaacaaaacgagtattattcgctggttaatcttcccgttttgctaggaccatca
agaaagaagtttattggtgatataactaatataccagtcgccaaggatagagatttcgtt
actggtgctattttatcttcagccttggcgaatggatgtgatatagtgagggtacatgat
gttcgtaataacagcaaagttctaaaactagcgaacgaattgtacagagactaa
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