KEGG   PATHWAY: ko00970
Entry
ko00970                     Pathway                                
Name
Aminoacyl-tRNA biosynthesis
Class
Genetic Information Processing; Translation
Pathway map
ko00970  Aminoacyl-tRNA biosynthesis
ko00970

Drug
D01076  Mupirocin (USP/INN)
D02195  Mupirocin calcium (USP)
D04413  Halofuginone hydrobromide (USAN)
D08034  Halofuginone (INN)
D09324  Bederocin (USAN/INN)
Orthology
K14218  tRNA Ala
K14219  tRNA Arg
K14220  tRNA Asn
K14221  tRNA Asp
K14222  tRNA Cys
K14223  tRNA Gln
K14224  tRNA Glu
K14225  tRNA Gly
K14226  tRNA His
K14227  tRNA Ile
K14228  tRNA Leu
K14229  tRNA Lys
K14230  tRNA Met
K14231  tRNA Phe
K14232  tRNA Pro
K14233  tRNA Ser
K14234  tRNA Thr
K14235  tRNA Trp
K14236  tRNA Tyr
K14237  tRNA Val
K14238  tRNA Sec
K14239  tRNA Pyl
K01885  glutamyl-tRNA synthetase [EC:6.1.1.17]
K14163  bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]
K09698  nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
K02433  aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
K02434  aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
K02435  aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
K09482  glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7]
K03330  glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7]
K03865  glutamyl-tRNA(Gln) amidotransferase subunit F [EC:6.3.5.7]
K01886  glutaminyl-tRNA synthetase [EC:6.1.1.18]
K01872  alanyl-tRNA synthetase [EC:6.1.1.7]
K22503  aspartyl-tRNA synthetase [EC:6.1.1.12]
K01876  aspartyl-tRNA synthetase [EC:6.1.1.12]
K24278  ergosteryl-3beta-O-L-aspartate synthase [EC:6.1.1.12 2.3.2.37]
K09759  nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
K01893  asparaginyl-tRNA synthetase [EC:6.1.1.22]
K01880  glycyl-tRNA synthetase [EC:6.1.1.14]
K01878  glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
K01879  glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
K14164  glycyl-tRNA synthetase [EC:6.1.1.14]
K01868  threonyl-tRNA synthetase [EC:6.1.1.3]
K01875  seryl-tRNA synthetase [EC:6.1.1.11]
K10837  O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164]
K03341  O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase [EC:2.9.1.2]
K01042  L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1]
K07587  O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
K06868  Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]
K01883  cysteinyl-tRNA synthetase [EC:6.1.1.16]
K01884  cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
K01874  methionyl-tRNA synthetase [EC:6.1.1.10]
K00604  methionyl-tRNA formyltransferase [EC:2.1.2.9]
K01873  valyl-tRNA synthetase [EC:6.1.1.9]
K01869  leucyl-tRNA synthetase [EC:6.1.1.4]
K01870  isoleucyl-tRNA synthetase [EC:6.1.1.5]
K04567  lysyl-tRNA synthetase, class II [EC:6.1.1.6]
K04566  lysyl-tRNA synthetase, class I [EC:6.1.1.6]
K11627  pyrrolysyl-tRNA synthetase [EC:6.1.1.26]
K01887  arginyl-tRNA synthetase [EC:6.1.1.19]
K01881  prolyl-tRNA synthetase [EC:6.1.1.15]
K01892  histidyl-tRNA synthetase [EC:6.1.1.21]
K01889  phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
K01890  phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
K01866  tyrosyl-tRNA synthetase [EC:6.1.1.1]
K01867  tryptophanyl-tRNA synthetase [EC:6.1.1.2]
Compound
C00025  L-Glutamate
C00037  Glycine
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00073  L-Methionine
C00078  L-Tryptophan
C00079  L-Phenylalanine
C00082  L-Tyrosine
C00097  L-Cysteine
C00101  Tetrahydrofolate
C00123  L-Leucine
C00135  L-Histidine
C00148  L-Proline
C00152  L-Asparagine
C00183  L-Valine
C00188  L-Threonine
C00234  10-Formyltetrahydrofolate
C00407  L-Isoleucine
C00886  L-Alanyl-tRNA
C01005  O-Phospho-L-serine
C01931  L-Lysyl-tRNA
C02047  L-Leucyl-tRNA
C02163  L-Arginyl-tRNA(Arg)
C02282  Glutaminyl-tRNA
C02412  Glycyl-tRNA(Gly)
C02430  L-Methionyl-tRNA
C02553  L-Seryl-tRNA(Ser)
C02554  L-Valyl-tRNA(Val)
C02702  L-Prolyl-tRNA(Pro)
C02839  L-Tyrosyl-tRNA(Tyr)
C02984  L-Aspartyl-tRNA(Asp)
C02987  L-Glutamyl-tRNA(Glu)
C02988  L-Histidyl-tRNA(His)
C02992  L-Threonyl-tRNA(Thr)
C03125  L-Cysteinyl-tRNA(Cys)
C03127  L-Isoleucyl-tRNA(Ile)
C03294  N-Formylmethionyl-tRNA
C03402  L-Asparaginyl-tRNA(Asn)
C03511  L-Phenylalanyl-tRNA(Phe)
C03512  L-Tryptophanyl-tRNA(Trp)
C06112  L-Glutamyl-tRNA(Gln)
C06113  L-Aspartyl-tRNA(Asn)
C06481  L-Seryl-tRNA(Sec)
C06482  L-Selenocysteinyl-tRNA(Sec)
C16138  L-Pyrrolysine
C16638  O-Phosphoseryl-tRNA(Sec)
C17022  O-Phosphoseryl-tRNA(Cys)
C17027  L-Pyrrolysyl-tRNA(Pyl)
Reference
PMID:18252769
  Authors
Sheppard K, Yuan J, Hohn MJ, Jester B, Devine KM, Soll D
  Title
From one amino acid to another: tRNA-dependent amino acid biosynthesis.
  Journal
Nucleic Acids Res 36:1813-25 (2008)
DOI:10.1093/nar/gkn015
Reference
PMID:15314242
  Authors
Polycarpo C, Ambrogelly A, Berube A, Winbush SM, McCloskey JA, Crain PF, Wood JL, Soll D
  Title
An aminoacyl-tRNA synthetase that specifically activates pyrrolysine.
  Journal
Proc Natl Acad Sci U S A 101:12450-4 (2004)
DOI:10.1073/pnas.0405362101
Related
pathway
ko00250  Alanine, aspartate and glutamate metabolism
ko00260  Glycine, serine and threonine metabolism
ko00270  Cysteine and methionine metabolism
ko00290  Valine, leucine and isoleucine biosynthesis
ko00300  Lysine biosynthesis
ko00330  Arginine and proline metabolism
ko00340  Histidine metabolism
ko00380  Tryptophan metabolism
ko00400  Phenylalanine, tyrosine and tryptophan biosynthesis
LinkDB

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