Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52): KPN_04340
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Entry
KPN_04340 CDS
T00566
Symbol
fadB
Name
(GenBank) 4-enzyme protein: 3-hydroxyacyl-CoA dehydrogenase; 3-hydroxybutyryl-CoA epimerase; delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase; enoyl-CoA hydratase
KO
K01825
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:
1.1.1.35
4.2.1.17
5.1.2.3
5.3.3.8
]
Organism
kpn
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52)
Pathway
kpn00071
Fatty acid degradation
kpn00280
Valine, leucine and isoleucine degradation
kpn00310
Lysine degradation
kpn00362
Benzoate degradation
kpn00380
Tryptophan metabolism
kpn00410
beta-Alanine metabolism
kpn00640
Propanoate metabolism
kpn00650
Butanoate metabolism
kpn00907
Pinene, camphor and geraniol degradation
kpn00930
Caprolactam degradation
kpn01100
Metabolic pathways
kpn01110
Biosynthesis of secondary metabolites
kpn01120
Microbial metabolism in diverse environments
kpn01200
Carbon metabolism
kpn01212
Fatty acid metabolism
Module
kpn_M00087
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:
kpn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
KPN_04340 (fadB)
00650 Butanoate metabolism
KPN_04340 (fadB)
09103 Lipid metabolism
00071 Fatty acid degradation
KPN_04340 (fadB)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
KPN_04340 (fadB)
00310 Lysine degradation
KPN_04340 (fadB)
00380 Tryptophan metabolism
KPN_04340 (fadB)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
KPN_04340 (fadB)
09109 Metabolism of terpenoids and polyketides
00907 Pinene, camphor and geraniol degradation
KPN_04340 (fadB)
09111 Xenobiotics biodegradation and metabolism
00362 Benzoate degradation
KPN_04340 (fadB)
00930 Caprolactam degradation
KPN_04340 (fadB)
Enzymes [BR:
kpn01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
KPN_04340 (fadB)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.17 enoyl-CoA hydratase
KPN_04340 (fadB)
5. Isomerases
5.1 Racemases and epimerases
5.1.2 Acting on hydroxy acids and derivatives
5.1.2.3 3-hydroxybutyryl-CoA epimerase
KPN_04340 (fadB)
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.8 Delta3-Delta2-enoyl-CoA isomerase
KPN_04340 (fadB)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
3HCDH_N
ECH_1
3HCDH
ECH_2
Motif
Other DBs
NCBI-ProteinID:
ABR79708
UniProt:
A6TGM4
LinkDB
All DBs
Position
complement(4748470..4750659)
Genome browser
AA seq
729 aa
AA seq
DB search
MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGHALDVLEKQSDLKGLLLRSE
KAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTISAVNGYALGGGCEC
VLATDYRLATPDLRIGLPETKLGIMPGFGGSVRLPRLLGADSALEIIAAGKDVGADQALK
IGLVDGVVAAEKLRDGALAILRQAMNGDLDWKAKRQPKLEPLKLSKIEAAMSFTIAKGMV
AQTAGKHYPAPITAVKTIEAAARLGREEALVLENKSFVPLAHTNEARALVGIFLNDQYVK
AKAKKLTKDVETPKHAAVLGAGIMGGGIAYQSAWKGVPVVMKDISDKSLTLGMTEAAKLL
NKQLERGKIDGLKLAGVISTIQPTLEYSGFDRVDVVVEAVVENPKVKKAVLAETESKVRP
DTVLASNTSTIPISELASVLQRPENFCGMHFFNPVHRMPLVEVIRGEKTSDNTIAKVVAW
ASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKVDKVMEKQFGWPMGPAYL
LDVVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDANRFGQKNGLGFWRYKDDSKGKP
KKEEDAAVDSLLADVSQPKRDFSDEEIIARMMIPMVNEVVRCLEEGIIASPAEADMALVY
GLGFPPFHGGAFRWLDTIGSAKYLDMAQQYQHLGPLYEVPAGLRDKARHNEAYYPQVEPA
RPVGALKTA
NT seq
2190 nt
NT seq
+upstream
nt +downstream
nt
atgctctacaaaggcgacaccctgtacctcgactggctggaagatggcatcgccgaactg
gtgttcgatgccccaggttcggtcaacaagcttgataccgcaaccgtagccagcctcggt
catgcgctggacgtactggaaaaacaaagcgatctcaaaggtctgctgctgcgctctgaa
aaagcggcatttatcgtcggcgcggatatcaccgaattcctctcgctgttcctggtccct
gaggagcagttaagccagtggctgcattttgctaacagcgtcttcaatcgtctggaagat
ctccccgtccccacaatctctgccgtcaatggctatgcgctgggcggcggttgcgaatgc
gtgctggcgaccgattaccgcctggcgacgccggatctgcgcattgggctgccggaaacc
aagctcggcattatgcccggcttcggcggttccgtgcgtctgccgcgcctgctcggcgcc
gatagcgcgctggaaattattgccgccgggaaagacgtcggcgccgatcaagcactgaaa
atcggcctggtggatggcgtggtcgctgcggaaaaactacgcgacggcgcgctggcgatc
ctacgtcaggccatgaatggcgacctggactggaaagcgaaacgtcagccgaagctggag
ccgctgaagctcagcaaaattgaagccgccatgagcttcacgattgccaaaggcatggtc
gcgcaaaccgccgggaagcattacccggcgccgatcaccgcggtcaaaaccattgaagcc
gccgcgcgtcttggtcgtgaagaagccctggtgctggaaaataaaagctttgtcccgctg
gcccataccaatgaggcccgcgcgctggttggtatcttcctgaacgaccagtacgtcaaa
gcgaaagcgaaaaagctgaccaaagatgtcgagacgccgaagcatgctgccgtcctgggc
gctggcattatgggcggcggtatcgcttaccagtcggcctggaagggcgtgccggtggtg
atgaaagacatcagcgacaaatcgctgaccctgggtatgaccgaagcggcgaaactgctg
aataaacagctggaacgcggcaaaatcgacggtctgaagctggccggagtgattagcacc
attcagccaacgctggaatacagcggttttgaccgcgtggacgtcgtcgttgaagcggtg
gtggaaaacccgaaagtgaagaaagccgtactagcggaaaccgagtcaaaagtgcgcccg
gataccgtgctggcgtccaacacctcaacgatccccatcagcgagctggccagcgttctg
cagcgcccggaaaacttctgcggtatgcacttctttaacccggtgcatcgcatgccgctg
gttgaagtgatccgcggcgaaaaaacctcggataataccattgccaaagtggtggcctgg
gccagcaaaatgggcaaaacgccgattgtggtgaatgattgtcccggcttcttcgtcaac
cgggtactgttcccctacttcgccggcttcagccagctgctgcgcgacggggcggacttc
cgcaaagtcgacaaagtgatggagaaacagtttggctggccgatgggcccggcttatctg
ctggacgtggtcggcatcgataccgcgcaccatgctcaggcggtcatggcggcgggcttc
ccgcagcggatgcagaaagattatcgcgacgccatcgacgccctgtttgacgccaaccgt
ttcggccagaagaacggcctcggcttctggcgctataaagacgacagcaaaggtaagccg
aagaaagaagaagatgctgccgtcgacagcctgctggccgacgtcagccagccgaagcgc
gatttcagcgatgaagagattatcgcccgcatgatgatccccatggttaacgaagtcgtc
cgctgcctggaagaaggcattatcgccagcccggcggaagcggatatggcgctggtatac
ggcctgggcttccctccattccacggcggcgcattccgctggctggacaccatcggcagc
gcgaagtatctcgatatggcgcagcaataccagcaccttggcccgctgtatgaagtgcca
gccggtctgcgtgacaaagcgcgccataacgaagcgtattatccccaggtagagccagcc
cgtccggttggcgctctgaaaacggcttaa
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