Lemur catta (Ring-tailed lemur): 123622421
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Entry
123622421 CDS
T08326
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat04120
Ubiquitin mediated proteolysis
lcat04144
Endocytosis
lcat04330
Notch signaling pathway
lcat04668
TNF signaling pathway
lcat04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
123622421 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
123622421 (ITCH)
04668 TNF signaling pathway
123622421 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
123622421 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
123622421 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
lcat04131
]
123622421 (ITCH)
04121 Ubiquitin system [BR:
lcat04121
]
123622421 (ITCH)
Enzymes [BR:
lcat01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
123622421 (ITCH)
Membrane trafficking [BR:
lcat04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
123622421 (ITCH)
Ubiquitin system [BR:
lcat04121
]
Ubiquitin ligases (E3)
HECT type E3
123622421 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
123622421
NCBI-ProteinID:
XP_045384732
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All DBs
Position
17:complement(23321985..23435246)
Genome browser
AA seq
862 aa
AA seq
DB search
MSNSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLNFRVWSHQTLKSDVLLGTAALDIYGTLKSNNMKLEEVVVTL
QLAGDKEPTETIGDLSICLDGLQLESEVVTNGETTCSESASQNEDGSRPKDETRVNTNGS
DDPEDAGAGENRRLDGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNTNTSEGATSGLIIPLTISGGSGPRPLNPVTQAPLPPGWEQRVDQHGR
VYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctaacagtggatcacaacttggttcaatgggcagcctgaccatgaaatcacaactt
cagatcactgtcatatcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtagaagtcacagtggatggacagtcaaagaagacagaaaaatgcaacaatacc
aacagtcccaaatggaagcaaccccttacagtgattgtcacccctgtgagtaaattaaat
tttcgtgtgtggagtcaccagacgctgaaatctgatgttttgttgggaactgctgcctta
gatatttatggaactttaaagtcaaacaatatgaaacttgaggaagtagttgtgactttg
caacttgcaggtgacaaagagccaacagaaacaataggagacttgtcaatttgtcttgat
gggctgcagttagagtctgaagttgttactaatggtgaaactacatgttcagaaagtgct
tctcagaatgaagatggctccaggccaaaggatgaaacaagagtgaacacaaatgggtca
gatgaccctgaggatgcaggagctggtgaaaataggaggctcgatggaaataattctcca
tcactctcaaatggaggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cccaccccacgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgat
ggatctagtacgggctctctgccaccaacaaatacaaatacaaatacatcggaaggagca
acatccggattaataattcctcttactatatctggaggctcaggccctaggccattaaat
cctgtaactcaagctcccctaccacctggttgggagcagagagtggaccagcacgggcga
gtttactatgtagatcatgttgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggaacggcgagttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccaacattggaatctgtccggaactatgaacagtggcag
ctacaacgtagtcaacttcaaggagcaatgcagcagtttaaccagagattcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatcctcttggccctttgcca
cctggatgggagaagagaacagacagcaatggcagagtatattttgtcaaccacaacact
cgaattacacagtgggaagaccccaggagtcaaggtcaattaaatgaaaagcctttacct
gaaggctgggaaatgagattcacagtggatggaattccttattttgtggaccacaataga
agaaccaccacttatatagatccccgcacaggaaaatctgccctagacaatggaccccag
atagcctatgttcgggacttcaaggcaaaggttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacattatttgaggattcc
tttcaacagataatgagcttcaatccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaagtcttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaaccctgcttcttacatcaatccagatcacctgaaatattttcgttttata
ggcaggtttattgccatggctctgttccatgggaaatttatagatacaggtttttcttta
ccattctataagcgtatcttgaacaaacctgttggtctcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaataacattgaggaatgtggtttg
gaaatgtacttctccgtcgataaagaaattctaggtgaaattaagagtcatgatttgaaa
cccaatggtggtaatattcttgtaacagaagaaaataaagaggaatacatcagaatggta
gctgaatggaggttatctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgatttgaacgactggcaaagacatgccatctaccgtcat
tacacacggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaatagataat
gagaagagaatgagacttctgcagtttgtaactggaacatgccgattgccagtaggagga
tttgctgatctcatggggagcaatggaccacagaaattctgcattgaaaaagttgggaaa
gaaaattggttacccagaagtcatacctgctttaaccgcctagacctgccaccatacaag
agctacgagcaactgaaggaaaagctgttgtttgccattgaagaaacagaaggatttgga
caagagtaa
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