Lemur catta (Ring-tailed lemur): 123635850 Help Entry 123635850         CDS       T08326                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism lcat  Lemur catta (Ring-tailed lemur) Pathway lcat04010   MAPK signaling pathway lcat04014   Ras signaling pathway lcat04015   Rap1 signaling pathway lcat04022   cGMP-PKG signaling pathway lcat04066   HIF-1 signaling pathway lcat04068   FoxO signaling pathway lcat04072   Phospholipase D signaling pathway lcat04150   mTOR signaling pathway lcat04151   PI3K-Akt signaling pathway lcat04152   AMPK signaling pathway lcat04211   Longevity regulating pathway lcat04213   Longevity regulating pathway - multiple species lcat04520   Adherens junction lcat04910   Insulin signaling pathway lcat04913   Ovarian steroidogenesis lcat04923   Regulation of lipolysis in adipocytes lcat04930   Type II diabetes mellitus lcat04931   Insulin resistance lcat04932   Non-alcoholic fatty liver disease lcat04960   Aldosterone-regulated sodium reabsorption lcat05010   Alzheimer disease lcat05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:lcat00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     123635850 (INSR)    04014 Ras signaling pathway     123635850 (INSR)    04015 Rap1 signaling pathway     123635850 (INSR)    04066 HIF-1 signaling pathway     123635850 (INSR)    04068 FoxO signaling pathway     123635850 (INSR)    04072 Phospholipase D signaling pathway     123635850 (INSR)    04022 cGMP-PKG signaling pathway     123635850 (INSR)    04151 PI3K-Akt signaling pathway     123635850 (INSR)    04152 AMPK signaling pathway     123635850 (INSR)    04150 mTOR signaling pathway     123635850 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     123635850 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     123635850 (INSR)    04923 Regulation of lipolysis in adipocytes     123635850 (INSR)    04913 Ovarian steroidogenesis     123635850 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     123635850 (INSR)   09149 Aging    04211 Longevity regulating pathway     123635850 (INSR)    04213 Longevity regulating pathway - multiple species     123635850 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     123635850 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     123635850 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     123635850 (INSR)    04932 Non-alcoholic fatty liver disease     123635850 (INSR)    04931 Insulin resistance     123635850 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:lcat01001]     123635850 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:lcat04090]     123635850 (INSR) Enzymes [BR:lcat01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      123635850 (INSR) Protein kinases [BR:lcat01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    123635850 (INSR) CD molecules [BR:lcat04090]  Proteins   123635850 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 B2 Motif Other DBs NCBI-GeneID:  123635850 NCBI-ProteinID:  XP_045404377 LinkDB All DBs Position 1:112905484..113024931 Genome browser AA seq 1383 aa AA seqDB search MGAGGRWGAAAAPLLVALAALLVGAAGHLYTGEVCPGMDIRNNLTRLHELENCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLVCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGC TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EMGSYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSFDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDVDPPLRSNDPKLQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTNATNPSVPLDPISVSNSSSQILLKWKPPSDPNGNITHYLVFWE RQAEDSELFQLDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDAAGECCTCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRKTSPGTGAEDPRPSRKRRSLGEIGNVTVAAVPTVPS FPNISSTSVPTSPEEQRPFEKVVNKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAY VSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLC VSRKHYALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEATHFYVTDYLDVPSNIAKIII GPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVP REKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMK GFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQM AAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLP VRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPE NCPDRVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKAPESEELEM EFEDMESVPLDRSSHCQREEAGGRDGGSSLGLKRNYEEHIPYTHMNGGKKNGRILTLPRS NPS NT seq 4152 nt NT seq  +upstreamnt  +downstreamnt atgggcgccgggggccggtggggggcggcggccgcgccgctgctggtggccctggccgcg ctgttggtgggcgccgcgggccacctgtacaccggagaggtgtgtcccggcatggatatc cggaacaacctcaccaggttgcacgagttggagaactgctctgtcatcgaaggacatttg cagatactcttgatgttcaagacgaggcccgaagatttccgagacctcagtttccccaaa ctcatcatgatcactgattacttgctgctcttccgggtctacgggctggagagcctgaag gacctgttccccaacctcacggttatccggggctcacgcctcttctttaactacgcgctg gtcatcttcgagatggttcacctgaaagagctcggtctgtacaacctgatgaacataacc cggggttctgtccgcatcgagaaaaacaacgagctctgctacttggccacgatcgactgg tcccgtatcctggattcggtggaggataattacatcgtgttgaacaaagatgacaacgaa gagtgtggggacatctgtccggggactgccaagggcaagaccaactgccctgccaccgtc atcaatgggcagtttgtggaacggtgttggactcacagtcattgccagaaagtttgccca accatctgtaagtcacacggctgtaccgccgaaggcctttgctgtcacagcgagtgcctg ggcaactgttccgagcccgacgaccccaccaagtgtgtggcctgccgcaacttctacctg gatggcaggtgcgtggagacctgcccgcctccatactaccacttccaggactggcgctgt gtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactcacgaaggcagggc tgccaccagtatgtcattcacaacaacaagtgcattccggagtgtccctctggatacacg atgaattccagcaacttggtgtgcacaccatgcctgggcccctgtcccaaggtctgccac attctcgaaggtgagaagaccatcgactcagtgacatctgcccaggagctccgaggatgc accgttgtcaacgggagtcttatcatcaacatccgagggggcaacaacctagcagctgaa ttagaagccaacctcggcctcattgaggaaatttcagggtatctaaaaatccgtcgatcc tacgcgctggtgtcactttccttcttccggaagttacgtctgattcgaggagagaccttg gaaatggggagctactccttctacgctttggacaaccagaacttaaggcagctctgggac tggagcaaacacaacctcaccatcactcagggcaagctgttcttccactataatcccaaa ctctgtttgtcagaaattcacaagatggaagaagtctcaggaaccaaggggcgccaggag aggaatgacatcgccctgaagaccaatggggaccaggcatcctgtgaaaatgaattactt aaattttcttacattcggacatcttttgacaagatcttgctgaaatgggagccatactgg ccccccgacttccgagacctcttgggcttcatgctgttctacaaagaggccccttatcag aatgtgacagagttcgatgggcaggatgcgtgtggctccaacagctggacagtagtggac gttgacccgcccctaaggtccaatgaccccaagctgcagaaccaccctgggtggctgatg cgtggtctcaagccctggactcagtatgccatctttgtcaagaccttggtcaccttctcg gatgaacgccggacttacggggccaagagcgacatcatttatgtccagacaaatgccacc aacccatccgtccccctggacccgatctcggtttctaattcctcgtcccagattcttctg aagtggaagcccccctccgaccccaacggcaacatcacgcactacctggttttctgggag aggcaggcagaggacagcgagctgttccagctggattattgcctcaaagggctgaagctg ccctctcggacgtggtctcccccgtttgagtctgaggactctcagaaacacaaccagagc gagtacgaggacgcggccggcgagtgctgcacctgcccgaagacggactctcagatcctg aaggagctggaggagtcctcgttcaggaagacgttcgaggattacctgcacaacgtggtt ttcgtccccagaaaaacctctccaggcactggtgctgaggatcctaggccatctcggaaa cgcaggtctcttggcgaaatcgggaacgtgacagtggccgccgtgcccaccgtcccaagt ttccccaacatctcctcaactagcgtgcccacgagcccagaggagcaacggcccttcgag aaagtggtgaacaaggagtcactggtcatctctggcctgcggcacttcacgggctatcgc atcgagctgcaagcttgcaaccaagatgcccccgaggaacggtgcagcgtggcagcctat gtcagcgccaggaccatgcctgaagccaaggctgatgatatcgtaggccctgtgacccat gaaatcttcgagaacaacgttgttcacttgatgtggcaggagccaaaggaacccaacggt ctgatcgtgctgtatgaagtgagttatcggcgatatggagatgaggagctgcatctctgt gtgtcccgcaagcattacgcactggagcggggctgcaggctgcgcgggctgtcgccgggg aactacagcgtgcgagtccgggccacctccctggcgggcaatggttcctggacagaagcc acccatttttacgtgacggactatttagacgtcccatcaaatattgcaaaaattatcatc ggccctctcatctttgtatttctcttcagtgtggtgattggcagtatttacttattcctg agaaaaaggcagccagatgggccgctgggaccgctgtacgcatcttcaaaccctgagtac ctcagtgccagtgatgtgtttccatgttctgtgtacgtgccggacgagtgggaggtgcct cgagagaagatcaccctcctccgggagctggggcagggctccttcggcatggtgtatgag ggcaacgccagggacatcgtcaagggcgaggcagagacccgggtggcggtgaagactgtc aatgagtcggccagtctccgggagcggatcgagttcctcaacgaggcttcggttatgaag ggtttcacctgccatcatgtggtccgcctcctgggggtggtgtccaagggccagccgacg ctggtggtgatggagctgatggctcacggggacctgaagagctacctccgatctctgcgg ccggaggctgagaataacccgggtcgccctccccctaccctgcaagagatgattcagatg gcggcagagatcgctgacgggatggcctacctgaatgccaagaagtttgtgcaccgggac ctcgcagctagaaactgcatggtcgctcacgatttcactgtcaaaatcggagactttgga atgaccagagacatctacgaaacggattactaccggaaagggggcaagggcctgctcccc gtacggtggatggcaccagagtccctgaaggatggggtctttaccacttcttccgacatg tggtcctttggcgtggtcctttgggaaatcaccagcttggcagagcagccttaccaaggc ctgtctaatgaacaggtgttaaaattcgtcatggatgggggatatctggatcaacccgaa aactgcccagatagagtcaccgacttgatgcgcatgtgttggcagttcaaccccaagatg cggccgaccttcctggagatcgtcaacctgctcaaggacgacctgcaccccagcttccca gaagtttccttctttcacagcgaggagaacaaggctcctgagagcgaggaactggagatg gagtttgaggacatggaaagcgtacccctggaccggtcctcacactgtcagagggaggag gcggggggccgggatggagggtcctcgctgggcctcaaacggaactatgaggagcacatc ccctacacccacatgaacgggggcaagaagaacgggcggattctgaccctgcctcggtcc aatccctcctaa

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