Lodderomyces elongisporus: PVL30_004050
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Entry
PVL30_004050 CDS
T01116
Symbol
HIS4
Name
(RefSeq) trifunctional histidinol dehydrogenase
KO
K14152
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:
3.6.1.31
3.5.4.19
1.1.1.23
]
Organism
lel
Lodderomyces elongisporus
Pathway
lel00340
Histidine metabolism
lel01100
Metabolic pathways
lel01110
Biosynthesis of secondary metabolites
lel01230
Biosynthesis of amino acids
Module
lel_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
lel00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
PVL30_004050 (HIS4)
Enzymes [BR:
lel01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.23 histidinol dehydrogenase
PVL30_004050 (HIS4)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.19 phosphoribosyl-AMP cyclohydrolase
PVL30_004050 (HIS4)
3.6 Acting on acid anhydrides
3.6.1 In phosphorus-containing anhydrides
3.6.1.31 phosphoribosyl-ATP diphosphatase
PVL30_004050 (HIS4)
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Gene cluster
GFIT
Motif
Pfam:
Histidinol_dh
PRA-CH
PRA-PH
DUF6019
Motif
Other DBs
NCBI-GeneID:
5231569
NCBI-ProteinID:
XP_001524356
UniProt:
A5E3Y9
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Position
5:complement(455028..457610)
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AA seq
860 aa
AA seq
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MSFPLLPFVSSPESSQVEEFSLTGAILLPYSSLKISKHWTRQFSNDLKIYVKVDPSVTVD
QITELLNTGVEKVFIYDIEQYKEATVNAGLPAARFATTNIDTAEAYLESSLIVSEKLNDV
KLYNNHENRTIYFDVSNSGTQEEVNALAKEGYTPIISADKLTTKKQEAGKISISSVFIDT
LVTDRPDGLFTTLVTSPAPEFTSLGVVYSSKDSIAAAIEEKVGVYQSRKRTHELWYKGKT
SGATQKLVAISKDCDSDVVQFIVESRKGYGFCHRETQYTCFGDEQVKSSGKGLVKLDKTL
SERFSEIDAAPEGSYTKRLFQDENLLIAKLKEELDELIDAKGNRDEVAWEAADLIYFVMT
WCVKNGVRLADVEKNLDVKSLKVTRRKGDAKPQYVQKEQEKKEEVKAKVEEKDLESNESY
EMEVIVADDITSSNVDKAMKRPVQKTSDIMKLVLPIIENVKTNGDKALIELTAKFDGVQL
TTPVLNAPFPQELMEISQEMKDAIDLSMANIEKFHRAQLPTEEVMTVETCPGVYCSRFAK
PIENVGLYVPGGTAVLPSTAMMLGVPAKVAGCKNIIIASPPARATGKLTPEVVYVAHKLG
AQKIVMAGGAQAVTAMAYGTESVIKCDKILGPGNQFVTAAKMYVQNDTQALCSIDMPAGP
SEVLVIADNNADADFVASDLLSQAEHGVDSQVILIGVDLTKEKLAAFQDAVKKQASVLPR
KEIVAKCLSHSFILLVKSYKEAFELSNQYAPEHLILQIDNAKSFVPSSIENAGSVFVGAL
SPESCGDYSSGTNHTLPTYGYARQYSGVNTATFQKFITSQDVTEKGLKSIGKAVMTLAHV
EGLEAHRRAVEVRMEKLGLL
NT seq
2583 nt
NT seq
+upstream
nt +downstream
nt
atgagctttccacttttaccatttgtctcatcgcccgagagctcgcaagtggaggaattt
agtctcacaggagcaattttgcttccatattcttcactcaagattagcaagcactggact
cgtcagttctcaaacgacttgaaaatttatgtcaaagttgacccctccgttacagttgac
caaatcactgagttattaaatactggtgtggaaaaagtgtttatttacgacattgaacaa
tacaaagaagctaccgtcaatgcaggattaccagcagcaaggtttgcaaccactaacatc
gacactgcagaagcttatcttgagtcgtcacttattgtgagtgaaaagttgaacgatgtt
aagttgtacaacaatcacgaaaacagaacaatttatttcgatgtttccaactctggaact
caagaggaggttaatgcattggccaaggaaggatacactcctattatttctgcagataaa
ttaaccacaaagaagcaagaggcagggaagatctctatatcatcagtgtttatcgacaca
ttggtcacagatagaccagatggattattcactacacttgttacttcccctgctccagaa
tttactagtttgggtgtcgtttactcttccaaggactctattgcagccgctattgaagaa
aaagttggtgtgtatcaatcgagaaagagaactcatgaattatggtacaagggaaagact
agtggtgctacacagaaactagttgccattagtaaggactgcgattccgacgttgtacaa
ttcatagttgagtcgcgtaaaggctacggattctgccacagggaaacgcaatatacatgt
ttcggagatgaacaagtgaaatcgtcaggtaagggcttggtcaagttggacaagacgttg
tccgaaagatttagtgagattgatgcggctcctgaaggatcgtataccaagcgattgttc
caggatgaaaacttgctcattgccaagttgaaagaagaattggacgaattgattgatgca
aagggcaatagggatgaagtcgcttgggaagccgcagacttgatttattttgtaatgaca
tggtgtgtaaagaatggggtacgattggcagatgtggagaagaatttggatgtcaagagt
ttgaaagtgacgagaagaaaaggtgatgctaagccgcaatatgtgcaaaaggagcaagag
aagaaagaggaagttaaggccaaggtagaagagaaagacttggaatccaacgaatcgtat
gaaatggaggttattgttgccgatgacattacttcttcaaatgtagacaaggctatgaag
agaccagttcaaaaaacatcagacattatgaagcttgtgcttccaattattgaaaatgtg
aaaacaaatggcgataaagcattaatcgaactcactgcaaaatttgacggtgtgcaactc
accactcctgtgttgaatgcacctttcccccaggaattgatggaaatttcacaagaaatg
aaagatgccattgatttatccatggccaacattgaaaaattccatagagctcaattgcct
actgaagaagtgatgactgttgaaacttgccctggagtttattgttcaagatttgctaaa
cctattgaaaatgtcggtctttacgttccaggtggtactgcagttttgccctcgacggca
atgatgttgggtgttccagctaaggttgcaggatgtaaaaacattattattgcatcacca
ccagctagagctactggtaaattaactcccgaggtcgtatatgttgctcacaagcttggg
gcccaaaagattgttatggcaggtggcgcgcaagcagttactgcaatggcatacggtaca
gaatccgttatcaagtgtgataagatccttggccctggtaaccaatttgttactgcagca
aagatgtacgtacagaatgacactcaagcgctctgttccattgatatgccagctggtcca
agtgaggtgcttgtgattgctgataacaatgccgatgcagactttgtcgctagtgatttg
ttgtcacaagccgaacatggtgttgattcacaagtcattctcattggtgttgacttgacg
aaagaaaaacttgcagctttccaagatgccgttaaaaaacaggcatctgtgttgccaaga
aaagaaattgttgccaaatgtctttcacattcattcatcttactcgtcaagtcctataaa
gaggcatttgagttatctaaccaatacgcaccagagcatcttatcttgcaaattgataac
gctaaatcttttgttccttcactgattgaaaatgcgggctcggtgtttgttggtgcattg
tcaccagaatcatgtggtgattattcatcgggaacaaaccatacattgccaacatatgga
tacgcaagacaatacagtggtgttaatactgctactttccagaagttcattacatcacaa
gacgtgactgaaaaaggattaaagagtattggtaaagcagtgatgacattggctcacgtt
gaaggattagaggcacatagaagagctgttgaagttaggatggagaaacttggattgctt
taa
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