Labeo rohita (rohu): 127156545
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Entry
127156545 CDS
T09007
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
lroh
Labeo rohita (rohu)
Brite
KEGG Orthology (KO) [BR:
lroh00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lroh01001
]
127156545 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
lroh04131
]
127156545 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
lroh04147
]
127156545 (lrrk2)
Enzymes [BR:
lroh01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
127156545 (lrrk2)
Protein kinases [BR:
lroh01001
]
Serine/threonine kinases: TKL group
LRRK family
127156545 (lrrk2)
Membrane trafficking [BR:
lroh04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
127156545 (lrrk2)
Exosome [BR:
lroh04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
127156545 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
LRR_4
LRR_8
COR
Roc
Ras
Ank_2
NBCH_WD40
Kdo
Ank_3
Ank_4
MMR_HSR1
Ank
Arf
LRR_9
Motif
Other DBs
NCBI-GeneID:
127156545
NCBI-ProteinID:
XP_050955421
LinkDB
All DBs
Position
25:complement(789629..831288)
Genome browser
AA seq
2537 aa
AA seq
DB search
MADKEELGIRLKKLLVRLNLQEGKQLGTIVQIIQDLLFLSHTDHCVELFADQNVHMPLML
VLSSHFNSKVQQVGWSLLCRLMEICPTTLDSLACPVENEFTEVHKQILKVLSMYPKDSKM
MMVGLRALSLLLKSGEIAMQVLHEEEQDVFFLILEAMRSFNDKEEVQLQGCAALQLLLQR
VSDAHLVEFIENKDHEVILNALRRFMDSENMVLQALRVLIPLAAPASNIEILMSKPVKCY
SLLCQAMDMWLDSEAIQVAGCCLLRKFTSESYYNILVLNGVHKVAVKACVSYPENATVQT
DAFSCLSALAECIVQNEGLDKEWNEEDEAKQKVLVKKVATQVEEMLIWREACYTALERHA
DNATVQEAACVALNSLLLHCNSSNHVELEGRPPLHSLIMAAMLLHSSSVKVFQAASCTLR
TLIQHHSRMRALLLSHGIHVNIVVLMRKHESSSAVCESACKLLHILFQGARASLDDAILI
LGQILIALKTHNFIPEVQLEGLRASLVLLNPDRSLREHGTSVADPDTVDVSLRVLKNQCV
LEGAHTVYLEALNRFISSVEIQECGLGVLSALADSSGAVDLMCQQGAIDTVLHTLQMFPQ
GRDVHYWGLSLLFHLISKKKLSRMMVPVLASVLVSSIRQHKEDTVMLLKGFQVVWKLLDT
CSSAAAWLQKEAFEKDIFQILRENMADQCRDPLQGMSCLCLSKMVADSEIMYALLERACE
DGDVDMAECLIQLGADINKKTKSDSLIYQVCDRGAPLALLELLVSAGVHEQQLRGALSVC
IRRGDDPAVTLLLTRLGLDHTNNALCLGSFRLGQMKAMWLSALLSERKTQSPVNKKKSKG
QRLARQILSIQRNKGFVGVGRLQSDASTSEYFTDEESDDSHVSLDESLAFMLDDMESDGS
DGPSQGLLLFNDSPEVGRKPAWRHSRRRRANSEGCRGDTNPSAPLHKRFNSHNTRGQGFI
ESSTPGAFPLAVDKEPIRLLDLSGNELGNLSCLMGMSALKQQIENLLRLDLSSNSLSEFP
SVLCQNLRSLTRLDLQGNQLQSLPVELLGLPALSTLNVSRNCIGPLLLLDPTVRSPALRQ
LNLSFNQITVFPFQLGQAMDRLEELSLEGNQISALSLPLCLAELKVLDISKNQVNIISDN
FLTECLKLETFNASVNQISSLSHLPPKITTVKLSQNNFTSVPEIVINLPNLRSVDMRNNS
ISDLPGPSFWVSVNLRELMFSHNQISVLDLSGPAYKWARLEKLHLSSNKLTEIPPQIGML
EDLTSLDVSQNEGLRSFPDEMGKLVHLWDLPLDGLQLQMNLKHIGNKTKDIIRFLQQRLK
KAVPYYRMKLMVVGSPRSGKSSLIHQLMKLKRSHWQSDQHTIGVSVRDWAIRNKDKRNML
LNVWEFSGGEECSGFHPHFMSSRALYLVLYDLSKGSSEIDTIKPWLFNIKAVAGQSPVIV
VGTHADVCEERHLQECVLKLREELMSQPGFPVIKENHILCACEESESISRLRKAICKELI
GFKIQSQPVMGQLIPDCYVELERRVLQERSHVPTDFPVLRHSRLLEIIQETQLQLEEGEL
PHAIHFLSEAGVLLHFDDPVLQLKDLYFIDPQWLCNIISQTLTLRSTGPWDGTRGVMQRT
TVEKFLNKSRCFPMDHLTQFFKLLEKFQIALPFGDDQLLIPSSLSDHRPVIELPHCENSE
VIVRLYEMPYFPMGYWPRQISRLLEVSAYLLYGKEKALRPNRIYWRKGIYLSWSAEAYCL
VEALSLEDNPASFIKITVPCSRKGCVLFGQVVDHIDSLLEEWFPGLLATDVHGAGETLLK
KWALYSFSDGQNCQKILLEDLLSKINADGLLVNPEDPSCTLPISQISPDLVLSDQPSSTI
LDPEQLEMELSMEYMLGDGGFGSVYKAVYKNEEVAVKIFNKHASTLYVHRLVRQELAVLG
RLCHPSLVGLLAAGCNPHILVMELAPCGSLDSLFERENSSLSRKLQHRIALHVADGLRYL
HSSMIIYRDLKPHNILLFNLKTDAEVIAKITDYGIAQYCCSMGVRSSEGTPGFRAPEVAR
GNVIYNVQADVYSFGLLLYDLLTYGERISDGMKFPSEFDEAAVQGKLPDPVKDYGCSPWP
GFESLMRVCLRENPQDRPTSAQVFDRLNSVKMLCLMRELTLMSFPGECFTVSGVSGGANG
GKNTRVWIGGGSSSQKLGCVTSLDLETGGSLSQEIDSSPILCMVIVRAPGSCSDWLVAGT
QSGSLYIMDTISAEVLHCLKSVKDSVTSLYFHTHRHLKNYLLVGTADGSLIIYEDSVLKV
KDGGPVKTLQVGDVNTPLMCIGPFSQNQERRELWAACGSRVFSLSVEYDMSRSIDTKPKH
LYTQQGRPSSDPCISRLAVDKHMYVSKRDGHTVEVWDKKTERMVNLIDCAQLLGLSPTKK
PKAQSEDQSRQMVPSSATVKALLVQHSGTLWIGTKAGHILLVEVSSCQLLQTISPHCHSI
RCMGSVLLADSLNRKNVILVLGRRQRMPQDQIKTQAPAEDSVLTVWNSSLPLEVRDLIRH
CELRDKITSKMRETLHG
NT seq
7614 nt
NT seq
+upstream
nt +downstream
nt
atggctgataaagaggagttagggatcaggctgaagaagctgctggtgaggttgaacctt
caagaggggaagcagttaggcaccatagtccagatcatacaggacctcctgttcctgtcc
catacggatcactgtgttgagctgtttgccgatcaaaacgtccatatgcctctgatgctg
gtgctgtcatcgcatttcaacagcaaagttcagcaggtaggctggtctctgctgtgtcgt
ctgatggagatctgtcccaccactctggatagtttggcctgcccagtggaaaatgagttt
actgaggtgcacaagcagattcttaaggtgctttccatgtatcctaaagactccaagatg
atgatggtgggcctgagagctctgtctctcctacttaagtcaggtgagattgcaatgcag
gttctgcatgaggaggaacaggatgtgtttttcttgattctggaggccatgagatcattc
aatgacaaagaagaggttcaactacaaggatgtgctgctttacaactactgctgcaaaga
gtttctgatgctcacctggtggagttcattgagaacaaggatcatgaggtgattttgaat
gcgctcagacggttcatggacagtgagaacatggtactgcaagctctgagggtcctcata
ccactggctgctccagccagcaatattgagattctgatgtccaaacctgttaaatgctac
agtctactgtgtcaggctatggacatgtggctcgactcagaggccatacaggtggccggt
tgctgtttgttacggaaatttacatcagagagttactataatatactggtgctgaatggt
gtccataaggtggcggtgaaagcatgtgtctcctatcctgaaaatgccacagtgcagacc
gatgccttttcctgcctaagcgctctcgcggagtgtattgtacagaatgaaggcctggac
aaagagtggaacgaggaggatgaagcaaaacagaaagttctggtaaagaaagtagccact
caagtggaagagatgctcatatggagagaggcctgttataccgctttagagagacatgct
gacaatgccacagtgcaggaagctgcgtgtgttgccctaaacagcttgctgcttcattgc
aactcatccaaccatgtggaactggaaggaaggcctcctcttcattctctcatcatggct
gccatgcttttgcattcatccagtgttaaggttttccaagctgcttcctgtacactacgt
acactaatacagcaccacagtaggatgcgggctctgctgctgtcacatggcattcatgtc
aacattgtggttctcatgcggaaacatgaaagctctagcgccgtgtgtgaaagtgcctgc
aaactgcttcacatcctcttccagggagcgagggccagtctagatgacgcgatcctaatt
ctcggtcagatcctgattgctctaaagacacataacttcattcctgaagttcagctggag
ggtctccgagcgagtttagtccttctaaacccagacaggagtttaagagaacatggcacc
tcggtggcggatcctgacacggtggatgtgtccctgcgggtgctgaagaaccagtgtgta
ctagagggagcccacactgtctatctagaggcacttaataggtttatcagtagtgtggag
attcaggagtgtggactcggtgtactctcagcattagctgactcttctggagcggttgac
ctaatgtgccagcagggggcgatagatacggttcttcatacgctgcagatgtttccacag
ggacgtgatgttcactactggggccttagtcttctgtttcacctcatctctaagaagaag
ctctctcgtatgatggtgcctgtactggcatcggttttggtgagctcaatacggcagcac
aaagaggatacagtcatgcttctaaagggatttcaagtggtgtggaagttgttggacacc
tgctcaagtgctgcagcatggctgcagaaagaagccttcgagaaagacatcttccagatc
ctgcgggaaaacatggcagaccagtgccgagatccactgcagggaatgagttgcctgtgc
ctgtctaagatggtggcggacagtgagatcatgtatgcgctgttggagagagcgtgcgaa
gacggtgacgtggacatggcagaatgtctcatccaactgggcgctgacatcaacaagaaa
acaaaaagcgattcgctcatatatcaggtttgtgatcgaggggctcctttggctttgctg
gaactgctggtttctgcaggtgttcatgagcagcagttacgtggagctctgagcgtgtgt
atcaggaggggcgatgaccctgcggtcaccctcctgctcacccgtctggggctggaccac
accaacaatgccctgtgccttgggagcttccgccttggacaaatgaaggcgatgtggctc
agtgctctgctctctgagcgcaagactcagtctccagtcaacaagaagaagagtaaaggt
cagcgtttggccagacagatcttgtcaatccagaggaacaaaggctttgtgggagttggt
agattacagagtgatgccagcacatcagaatatttcacggatgaggaaagtgacgactca
cacgtttccttagatgaaagcttggccttcatgcttgatgacatggagagtgacgggagt
gacgggccttcacaaggattgttgcttttcaacgattcaccagaagtgggcagaaaacct
gcttggagacatagcaggcgtagacgtgccaattcagagggatgccgtggtgacacaaat
ccaagtgctcctctgcataagcggtttaattctcacaacactagagggcaggggttcatt
gaaagctccactccaggtgcttttcctctggctgtagacaaagagcctatccgtctgctc
gacctctcgggcaacgagctgggcaatctgtcctgtttgatgggtatgagcgctctcaaa
cagcagattgaaaaccttcttcgacttgatttgagcagcaacagtctatcagagtttccc
agtgttctctgtcagaatttaagaagtcttactcgtttagatcttcaaggtaaccaactg
cagtcacttcctgtggaactcctgggtttgcctgcactgagcacgcttaatgtttctcgc
aactgcattggtcctcttctgctgctggacccaactgtgcgcagtccagccttacgccag
ctcaacctctccttcaaccagatcaccgtcttccccttccagttggggcaagccatggac
agactggaggagctctcgttggagggcaatcagatatcagcactgtctctcccgctctgc
ctggctgaattgaaagttttagacatcagtaagaatcaagttaatataatttcagacaac
tttctcactgaatgtctcaagctggaaactttcaacgcttcagttaaccaaatcagttca
ttgtcacaccttccccccaaaataaccactgttaaattgtcacagaacaatttcacaagt
gttcctgaaatagtcatcaacttgccaaatttgcgttcggtggatatgagaaataacagt
attagtgatctgccgggtccatcgttctgggtcagtgtaaacctaagagagctgatgttc
agtcataatcaaatctctgtgctcgacctgagcggcccggcatacaagtgggccagactg
gagaaacttcatttaagctccaacaaactcactgagattcctcctcagatcggtatgttg
gaggatcttacgtctctagatgtgagtcagaatgaaggtttgcgctctttccctgatgag
atgggaaagctggttcatttatgggatctacctctagatggtctgcagctccagatgaac
ctcaaacatattgggaacaaaaccaaagatatcatcaggttcttgcagcagcgtctgaag
aaagctgtcccgtattaccgcatgaaactcatggtggtcggcagcccacgtagtgggaaa
agctctttgattcatcagctgatgaaactcaaacgctctcactggcaatctgatcagcac
accatcggcgtcagtgtcagagactgggccatcagaaacaaagacaagagaaatatgctc
ctgaatgtttgggagttctcaggtggtgaggaatgcagtgggtttcaccctcattttatg
agctccagggctctctatctagtactgtatgacctgagtaaaggatccagtgagatagac
accataaaaccctggctctttaacattaaagctgtagctggacagtcccctgtgattgtg
gttggaactcatgcagatgtgtgtgaagagcgccacctacaggagtgtgttctgaagctg
cgagaggagctgatgtctcaaccagggtttccagtgattaaagagaatcacatactgtgt
gcctgtgaggagtctgagtccatcagcaggttgcgcaaagccatctgtaaagagctcatt
gggttcaagattcagagtcagccggtaatgggacagttgattccagactgttatgtggag
ctggagaggagagttttacaggagaggtcacatgtacccactgatttcccagtgctcaga
cacagcagactactggagatcatacaggaaacacagctgcagctagaggagggagagtta
ccccatgctatccactttctcagtgaagctggtgtcctgctgcactttgatgatccggtg
cttcagctaaaggatttgtacttcattgacccacaatggctttgtaacatcatctcacag
acactgactctgaggagcactggtccgtgggacggcactagaggagtgatgcagcgaacc
actgtagaaaagtttctgaacaaaagtcgctgttttccaatggatcatctgactcagttc
ttcaaactattggaaaagtttcaaatagctctgccctttggagatgaccagttacttata
cccagcagcctgtcagatcacaggccggtgattgagctcccccactgtgagaattcagag
gtgattgttcggctttatgagatgccgtatttccccatgggctactggcccagacagatc
agccgtctgttggaagtgtctgcttacctgctctacggcaaagaaaaagcactgagaccg
aacaggatctactggaggaaaggcatctatctaagctggtctgccgaagcttactgtctg
gtggaggccttgtctctagaagacaaccctgctagcttcatcaagatcaccgtcccctgc
tctcgcaaaggttgtgtcttgtttggtcaggtggtggatcacattgactctttgcttgaa
gaatggtttccaggcctcctcgccactgatgtccatggcgctggagagacactgcttaag
aaatgggctctgtacagcttcagtgatggacaaaactgccagaagatcctgctggaagat
ctactctccaaaatcaatgcagatggtttgctggtcaacccagaggaccccagctgtact
ctgcccatctctcagatctctccagacctggtattgagtgaccagccgtccagcaccata
ctggatccagagcagttggaaatggagctctccatggagtatatgttgggagatggaggc
ttcggctctgtatataaagctgtttacaagaatgaggaagttgctgtaaagattttcaat
aaacatgcatctacactttacgttcatcggctggtacgacaggaactggcagtacttggc
agactgtgtcaccctagtctggtggggcttttggctgctggttgtaacccgcacattctt
gtaatggaactcgccccatgtggctctctggactcactcttcgagcgtgaaaatagcagt
ctcagccgcaaactacagcacaggatagcactgcatgtggcggatggtctcagatatttg
cactcatctatgattatctaccgagatctgaagccgcacaacattctgttatttaacctg
aagacggacgctgaggtcatcgctaaaatcacagactatggcatagcacagtactgctgc
agtatgggcgtccgcagctcagaaggaacaccaggttttagagccccggaagttgcccga
ggtaatgtcatctataacgtccaggcagatgtatattcgtttggtttgctgctgtatgac
cttttgacttatggcgagcggatatctgatggaatgaagtttcccagtgagtttgatgag
gcagctgtgcaaggaaaactaccagatccagttaaagattacggctgttctccatggcca
gggtttgagtctttgatgagagtctgtttgagagaaaacccacaggacagacccacatct
gctcaggtgtttgatcgtctgaattctgttaagatgctttgtctaatgcgagagctgaca
ttgatgagtttcccgggggagtgtttcactgtctccggtgttagcggaggtgcaaacgga
ggtaaaaatactcgtgtgtggattggaggtggcagttctagccagaaattgggctgtgtg
acatcactggatctggagacagggggaagcttgagccaggagattgacagtagtcctatc
ctctgcatggtgatcgtcagagctccagggtcatgcagtgactggttagttgctggcaca
cagtcaggttcactctacatcatggatactataagcgcagaggttctgcactgtctgaag
agtgtgaaggactctgtgacatcactatactttcacactcacagacatttaaagaattac
cttttggtcgggacagcagatggatcactaatcatttatgaagattcagtcctgaaggtg
aaggatggtggtccagtgaaaacgctgcaggttggtgatgtgaacactcctctgatgtgt
attggtccattcagtcagaatcaggagcgcagagagctgtgggcggcctgtggcagcagg
gtgttctcactctcagtggaatatgacatgagtagaagcatagacaccaaacccaaacat
ctgtacacgcagcaaggtcgacccagcagtgatccgtgcatatcacgtttagcggtggac
aaacatatgtatgtaagtaaaagggacggccacactgtggaggtctgggataagaagact
gagaggatggtgaacctcattgactgcgcacagttactcggattaagtcccaccaaaaag
cccaaagcccagagtgaggaccagtctagacaaatggtgccatcttcagcgactgttaaa
gctctgttggtccagcacagtggtactctttggattgggaccaaagcaggacacatcctg
ttggtggaagtctccagctgtcagctactgcagaccatcagccctcactgccactccata
cgctgcatgggctcagtgctgctagctgactcactcaaccgaaagaatgttattctagtg
ctgggtagacggcagcgcatgccacaagaccaaatcaaaacacaagccccagctgaggat
tcagtgctgacggtgtggaatagttcacttcctctcgaggtcagagatctgatcagacac
tgtgagctacgagacaagatcaccagcaaaatgagagaaacgctccacggctga
DBGET
integrated database retrieval system
