Mycobacteroides abscessus ATCC 19977: MAB_3294c
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Entry
MAB_3294c CDS
T00657
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit (Leu2)
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mab
Mycobacteroides abscessus ATCC 19977
Pathway
mab00290
Valine, leucine and isoleucine biosynthesis
mab00660
C5-Branched dibasic acid metabolism
mab01100
Metabolic pathways
mab01110
Biosynthesis of secondary metabolites
mab01210
2-Oxocarboxylic acid metabolism
mab01230
Biosynthesis of amino acids
Module
mab_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mab00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MAB_3294c
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MAB_3294c
Enzymes [BR:
mab01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MAB_3294c
4.2.1.35 (R)-2-methylmalate dehydratase
MAB_3294c
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
CAM63370
UniProt:
B1MDQ1
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All DBs
Position
complement(3332708..3334150)
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AA seq
480 aa
AA seq
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MTSVQQPRTLAEKVWDSHVVVRGTGEGEAREPDLIYIDLHLVHEVTSPQAFDGLRLAGRQ
VRRPDLTIATEDHNVPTIDIDKPIADPVSRTQVETLRKNCEEFGIRLHPMGDAEQGIVHV
VGPQLGLTQPGTTVVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFRTMAINI
DGSLPTGVTSKDVILAVIAKIGTGGGQGYVLEYRGQAVEEMSMEARMTMCNMSIEAGARA
GMVAPDETTYAYLKDRPHAPKGQLWDAAVAEWDSLRTDEGAQFDAEVHIDASTLTPFVTW
GTNPGQGVPLGADVPDPELMADEEERLAAEKALTYMDLTPGTPMREIPVDTVFVGSCTNG
RIEDLRAVADVLRDRKVAAGVTMLIVPGSMRVRAQAESEGLGEIFAAAGAQWRQAGCSMC
LGMNPDQLSPGQRCASTSNRNFEGRQGKGGRTHLVSPAVAAATAVRGKLSSPADLAKSVK
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atgactagtgtccaacagcccaggaccctggcagagaaggtctgggactcccacgtagtg
gtacgcggaaccggtgagggtgaggcgcgcgagcccgatctcatctatatcgacctgcac
ttggtgcacgaggtgaccagtccgcaggcattcgatggtcttcggctcgctgggcgccag
gtgcgccggccggacctgacgatcgcgaccgaagaccacaatgtgccgacgatcgacatc
gacaagccgatcgccgatccggtgtcccgcacccaggttgagacccttcggaagaactgc
gaagaattcggcatccgcctgcatcccatgggggatgccgagcagggcatcgtgcacgtg
gtcggtccgcagctgggattgacgcagccgggtaccacggtggtgtgtggcgacagccac
acctccacgcatggcgcgttcggggcgctggcgatgggtattgggacgtccgaagtggag
catgtgctggccacgcagaccttgccgttgaggccatttcggaccatggcgatcaacatc
gatggcagcctgccgaccggtgtcaccagcaaggacgttattttggccgtcatcgccaag
atcggcaccggcggggggcaggggtatgtcctggagtatcgcgggcaggccgtcgaggag
atgtcgatggaggcccgaatgactatgtgcaatatgtctattgaggcgggtgcccgggcg
ggaatggtcgcgcccgacgagacgacatatgcctatctgaaggaccgtccgcacgccccc
aaggggcagctgtgggatgccgctgtggccgaatgggactcgttgcgcaccgacgagggt
gcccagttcgacgccgaagtacacattgatgccagtactttgacgcccttcgtcacctgg
ggcaccaatcccgggcagggggtgcctctgggcgctgacgtgcccgatcctgagctgatg
gccgacgaggaagagcggctggcggccgagaaggcgctgacctacatggatctcactccg
ggtacccccatgcgtgagatcccggtggacaccgtgttcgtcgggtcctgcaccaacggg
cggatcgaggacctacgggccgtcgcggacgtgctgcgggaccggaaggtggccgcaggg
gtcaccatgctcatcgttcccggctcgatgagggtgcgtgcacaggccgaatccgagggg
ctgggcgagattttcgccgccgccggtgcccaatggcgccaggcgggctgttcgatgtgc
ctgggcatgaaccccgaccagctttccccgggtcagcggtgtgcgtcgacgtcgaaccga
aatttcgaaggacggcagggtaagggcggtcgcacccacctggtatcgccggccgtcgcc
gcggccacggcggtgaggggaaagctctcatcgccagctgatttggcaaaatccgtaaaa
tag
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