Mycobacteroides abscessus subsp. bolletii 50594: MASS_4003
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Entry
MASS_4003 CDS
T02682
Name
(GenBank) uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mabb
Mycobacteroides abscessus subsp. bolletii 50594
Pathway
mabb00860
Porphyrin metabolism
mabb01100
Metabolic pathways
mabb01110
Biosynthesis of secondary metabolites
mabb01120
Microbial metabolism in diverse environments
mabb01240
Biosynthesis of cofactors
Module
mabb_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mabb_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mabb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MASS_4003
Enzymes [BR:
mabb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MASS_4003
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MASS_4003
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AGM30605
UniProt:
R4UWX2
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Position
complement(3999940..4001589)
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AA seq
549 aa
AA seq
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MTRGRKKPGRILFVGSGPGDPGLLTVRARAVLTGATVAFTDPDVPQAVLDLVGSAVELPE
PAPAKPATGGDEAPAAANNEAAAEPPLTIDIRPALGDPADVAKTLVAEARSGVDVVRLVA
GDPLSIDSVLAEVHAVTRTQVAFEILPGLASSTAVPAYAGLPPGSAHTVADVRGDVDWAA
LAAAPGPLILHATPTHVPDAAKALIEHGLADQTLVAVTAQGTTCAQRTVETTLASLIDGV
PVDANDPHGPMTGALVLTIGRVVAGRSKLNWWESRALYGWTVLVPRTKDQAGEMSDKLVG
YGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRYQWVVFTSTNAVRAVWEKFAEFGLDAR
AFSGVKIACVGQATADKVRAFGINPELVPAGEQSSLGLLDEFPPYDDVFDPVNRVLLPRA
DIATETLAEGLRERGWEIDDVTAYRTVRAAPPAAQTREMIKTGGFDAVCFTSSSTVRNLV
GIAGKPHARTIVACIGPKTAETAVEFGLRVDVQPETAAVGPLVEALAEHAARLRTEGALP
PPRKKSRRR
NT seq
1650 nt
NT seq
+upstream
nt +downstream
nt
atgaccagggggcgcaagaagccagggcgcattctgttcgttggttccggacctggagac
cccggtctgttgaccgtccgggcgcgcgcggtgctcacaggtgccacggtcgcgttcacc
gatcccgatgtgccgcaggcggtactcgatctcgtggggtcggcggtcgaacttcctgaa
cccgcgcccgccaaaccggcgacgggaggcgatgaggctcccgccgcggcgaataacgaa
gccgctgccgagccgccgctcaccatcgacattcgccccgccttgggtgatccggccgat
gttgccaagacactcgtcgccgaggcccgcagcggtgtggacgtggtgcggttggtcgcc
ggcgacccactctcgatcgattcggtgctcgccgaggtccatgccgtcacgcggacccag
gtggcctttgaaatcctgcccggcctcgcttcgagcaccgcggtgcccgcctacgcgggc
ctgcccccgggctcggcccacaccgtggccgatgtgcgcggcgacgtggattgggcggcc
ctggccgctgctcctggcccgctgattctgcacgcgaccccgacgcatgtgcccgacgcc
gccaaggcgctcatcgagcatggcctggccgaccagactctggtcgcggtcaccgcgcag
ggcaccacgtgcgcacagcgcaccgtggagaccacactggcctcgctgatcgacggcgtc
ccggtggacgccaacgacccgcacgggccgatgaccggcgccctggtgctgacgatcggc
cgcgtggtcgccggccgctcgaagctgaactggtgggaaagccgtgccctgtacggctgg
accgtgttggtgccccgtaccaaggatcaagctggcgagatgagcgacaagctcgtcggg
tacggcgccttgcccgtcgaggtgccgaccattgccgtcgaacccccgcgcagtccggcc
caaatggaaagggctgtgaagggtttggtcgacggccggtaccagtgggtggtgttcacc
tccaccaacgcggtgcgtgccgtgtgggagaagttcgccgagttcggcctggacgcccgt
gccttctccggtgtgaagatcgcgtgtgtgggccaggcgaccgccgacaaggtgcgcgcc
ttcggcatcaacccggagctggttcctgccggtgagcagtcctcgctaggcctgctcgac
gagttcccgccctacgacgacgttttcgatccggtgaaccgggtgctgttgccgcgggcc
gacatcgccaccgagacccttgccgagggactgcgggaacgcggctgggagatcgacgac
gtgaccgcgtaccgcaccgtgcgcgcggccccgccggcggcgcagacccgcgagatgatc
aagaccggtgggttcgacgcggtctgtttcacctcgagctctacggttcgcaacctggtg
ggtatcgcgggcaagccgcatgcacgcaccattgtggcgtgcatcgggccgaaaaccgct
gagaccgcagtcgaattcgggttgcgagtggatgtgcagccggagacagcggccgtgggc
ccgctggtcgaggccctcgccgagcacgccgcccggctgcgcaccgaaggtgcactgccg
ccgccgcgtaagaagagccggcggagataa
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