Mycobacterium adipatum: A7U43_26395
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Entry
A7U43_26395 CDS
T09402
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
madi
Mycobacterium adipatum
Pathway
madi00860
Porphyrin metabolism
madi01100
Metabolic pathways
madi01110
Biosynthesis of secondary metabolites
madi01120
Microbial metabolism in diverse environments
madi01240
Biosynthesis of cofactors
Module
madi_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
madi_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
madi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
A7U43_26395
Enzymes [BR:
madi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
A7U43_26395
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
A7U43_26395
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ANE82313
UniProt:
A0A172UTI8
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Position
complement(5547065..5548732)
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AA seq
555 aa
AA seq
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MTGHAGSRGRKIRPGRITFVGSGPGDPGLLTTRARTVLANAATVFTDPDVPEAVLALVGS
ELPPTSGPAPHAPASDSDGGEAPAVLPGGADVRPALGDPAEVAKTLAAEARHGVDVVRLV
AGDPLSVDAVITEVNTLARTHLNFEIVPGLPDTTAVPTYAGLPLGSSHTVADVRDPNVDW
AALAAAPGPLILHATASHLADAARTLVEFGLAENTPAVVTAHGTTCQQHSVETTLSGLGD
KAILTAAESTGGTPGPLAGPLVVTIGKTVANRAKLNWWESRALYGWTVLVPRTKDQAGEM
SDRLVTHGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFNE
FGLDARAFSGVKIACVGQATADRVRAFGINPELVPTGEQSSLGLLDEFPPYDEIFDPVNR
VLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAHTREMIKTGGFDAVCFTSSS
TVRNLVGIAGKPHARTIVACIGPKTAETAVEFGLRVDVQPETAAVGPLVEALAEHAARLR
AEGALPPPRKKSRRR
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
atgactgggcacgcaggtagccggggccgaaagatccggcccggccgtatcacgttcgta
ggctccggcccgggcgatccaggcctgctgacgacacgtgcgcggacggtactcgccaac
gccgcgacggtgttcaccgaccccgatgtacccgaggcggtgctggcgctggtcggttcc
gagttgccgcccacctccgggcccgcaccgcacgctcccgcgtcggactccgatggcggc
gaggcgcccgcggtgctgcccggtggcgccgatgtgcgtcccgcgctgggcgacccggcc
gaggtcgccaagacgctggccgccgaggctcgccacggtgtggacgtggttcggctggtg
gcgggcgatccgctgtcggtcgacgcggtcatcaccgaggtcaacacgctggcgcgaacc
cacctgaacttcgagatcgtgcccgggctgccggataccacggccgtgccgacctatgcc
ggcctgccgctggggtcctcgcacacggtggccgatgtccgtgacccgaacgtggactgg
gccgcgctggccgccgcacccgggccgctgatcctgcacgccaccgcctcgcatctggcc
gacgcggcgcgcaccctggtggagttcggcctggccgagaacactcccgccgtcgtcacc
gcgcacggcaccacctgccagcagcattcggtggagaccacgctgtccggcctgggggac
aaggccattctgaccgcggccgagtccaccggcggtacccccggtccgctggcgggtccg
ttggtggtgacgatcggcaagaccgttgccaaccgggccaagctgaactggtgggagagc
cgcgcgctgtacggctggaccgtgctggtgccgcgcaccaaggatcaggccggcgagatg
agcgatcgcctggtcacccacggcgcactgcccgtcgaggtgcccaccatcgccgtcgag
cccccgcgcagccctgcccagatggaaagggccgtaaagggtttggtggacggccggttc
cagtgggtggtgttcacctcgaccaacgcggtgcgtgcggtgtgggagaagttcaacgag
ttcggcttggacgcgcgcgcattctccggcgtgaagatcgcctgcgtcggtcaggcaacc
gccgaccgggtccgcgccttcggtatcaatccggagctggtgcccaccggtgagcagtcc
tcgctcggcctgctcgacgagttcccgccctatgacgagattttcgatccggtgaaccgc
gtgctgctgccgcgcgccgatatcgcgaccgagacgctggccgagggcctgcgtgaacgt
ggttgggaaatcgaggatgtcaccgcctaccgcaccgttcgggccgcaccgccgccggcg
catacccgcgagatgatcaagaccggcggattcgacgcggtctgcttcacctcgagctcc
acggtgcgcaacctggtcggtatcgcggggaagccgcacgcacggaccatcgtcgcgtgc
atcggtcccaagacggcggaaacggccgtggaattcggcctgcgcgtcgatgtgcagccg
gagacggccgcggtcgggccgctggtcgaggcgctcgccgagcatgctgcgcgactgcgg
gccgagggcgcactgcccccgccgcgcaagaagagccgccggcgctag
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