Mycolicibacterium aichiense: MAIC_48680
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Entry
MAIC_48680 CDS
T06903
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
maic
Mycolicibacterium aichiense
Pathway
maic00860
Porphyrin metabolism
maic01100
Metabolic pathways
maic01110
Biosynthesis of secondary metabolites
maic01120
Microbial metabolism in diverse environments
maic01240
Biosynthesis of cofactors
Module
maic_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
maic_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
maic00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MAIC_48680 (hemD)
Enzymes [BR:
maic01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MAIC_48680 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MAIC_48680 (hemD)
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GFIT
Motif
Pfam:
HEM4
TP_methylase
LpxD
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BBX10065
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Position
complement(5008484..5010145)
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AA seq
553 aa
AA seq
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MTGHVSGRGRKAKPGHITFVGSGPGDPNLLTTRARTVLANAALVFTDPDVPPAVLSVVGT
DLPPASGPAPAPDGPPADGHDETAPPVVSVGPDVRPALGDPAEVAKTLVHEAKAGFDVVR
LVAGDPLSVDSVITEVNAVARAHAEFEIVPGLPATSAVPTYAGLPLGSAHTVADVRGEVD
WAALAAAPGPLILTASASHLPESARTLIEYGLAEATPCVVTSNGTTCGQRSVETTLHGLT
DRATLACNSDPAGPLTGTLVVTIGKTVAHRAKLNWWESRALYGWTVLVPRTKDQAGEMSD
RLVGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRYQWVVFTSTNAVRAVWEKFGEFG
LDARAFSGVKIACVGEATADRVRAFGVSPELVPAGEQSSLGLLDEFPEYDSIFDPVNRVL
LPRADIATETLAEGLRDRGWEIEDVTAYRTVRAAPPPAETREMIKTGGFDAVCFTSSSTV
RNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAARLRAE
GALPPPRKKSRRR
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atgactggtcatgtgagcggtcggggacgcaaggcgaagccgggacacatcacgttcgtc
ggctcgggtccgggcgaccccaacctgttgacgacgcgagcccgcaccgtgttggccaac
gccgcgctggtgttcaccgatcccgacgtgccgccggccgtcctgagcgtggtcggcacc
gacctgccgccggcgtcggggcccgcacccgcaccggacggcccccctgccgacggccat
gacgagaccgcgccgcctgtggtctccgtcggccccgacgtccggcccgcgctcggcgac
ccggccgaagtagccaagacgctggtccacgaggccaaggcaggcttcgacgtggtgcgc
ctggttgccggtgatccgctgtcggtggattcggtcatcaccgaggtcaacgccgtcgcc
cgcgcccacgccgagttcgagatcgttccgggcctgcccgccaccagcgcggtcccgacc
tacgcgggtctgccgctgggatcggcgcacaccgtcgccgacgtgcgcggcgaggtcgac
tgggcggccctggccgccgcacccggcccgctgatcctcaccgcgagcgcctcgcacctt
cccgagtccgcgcgcaccctgatcgagtacggcctggccgaggccacgccgtgcgtggtg
acctccaacggcaccacctgcggtcagcgttcggtcgagaccaccctgcacggcctgacc
gaccgcgccaccctggcctgcaacagcgatccggccggtccgctgaccggcacgctggtg
gtcaccatcggcaagacggtggcgcaccgcgcgaagctgaactggtgggagagccgggcg
ctgtacggctggaccgtcctggtgccgcgcaccaaggaccaggcaggcgagatgagcgac
cggctggtcggccacggcgcgctgcccatcgaagtgcccaccatcgccgtcgagccgccg
cgcagcccggcccaaatggaaagggccgtcaagggtttggtggacggccgctaccagtgg
gtggtgttcacctccaccaacgcggtgcgcgcggtgtgggagaagttcggcgagttcggc
ttggacgcgcgggctttctccggcgtcaagatcgcctgtgtcggcgaggcgaccgccgac
cgggtccgcgccttcggtgtcagccctgagctggtcccggccggtgagcagtcctcactc
ggtctgctcgacgaattcccggagtacgacagcattttcgatccggtgaaccgggtgctg
ctgccgcgtgccgacatcgccaccgaaaccctggccgaaggtctgcgcgaccgcggctgg
gagatcgaagacgtcaccgcctaccgcaccgtgcgtgcggcgccgccgccggccgagacc
cgcgagatgatcaagaccggcgggttcgacgcggtgtgcttcacctcgagctcgaccgtg
cgcaacctggtcggtatcgccggcaagccgcacgcccgcaccatcgtggcgtgcatcggg
ccgaagacggcggagacggctgcggaattcgggctgcgggtcgacgtgcagccggagacg
gctgcggttggtccgctggtcgatgcactggccgagcacgccgcccggctgcgtgccgag
ggcgcgttgccgccgccgcgcaagaagagccgacgccgctaa
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