Methanogenic archaeon ISO4-H5: AR505_0634
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Entry
AR505_0634 CDS
T04272
Name
(GenBank) 3-isopropylmalate dehydrogenase LeuB
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
marc
Methanogenic archaeon ISO4-H5
Pathway
marc00290
Valine, leucine and isoleucine biosynthesis
marc00660
C5-Branched dibasic acid metabolism
marc01100
Metabolic pathways
marc01110
Biosynthesis of secondary metabolites
marc01210
2-Oxocarboxylic acid metabolism
marc01230
Biosynthesis of amino acids
Module
marc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
marc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
AR505_0634
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AR505_0634
Enzymes [BR:
marc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
AR505_0634
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
DUF6875
Motif
Other DBs
NCBI-ProteinID:
AMH94355
UniProt:
A0A0X8V0J5
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All DBs
Position
642620..643765
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AA seq
381 aa
AA seq
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MKHFAIIPGDGIGKEVIAAGMDVLDAVSQISSFEYDGENFDIGSDRYLRTGELLTDQDVS
DLKKKDAIYFGAIGDPRVKPGILEGGILLKMRAVFDQYINLRPVTSWFPLVPLKREVNFD
IHFLRENTEDFYMGLGKRFGPSYSDKKNADGSYDVELGVKRESYNMDFKVNAHPTADDDY
SIEIGLVSRKGITRWADYAMKYALARGDDKVTLVDKANVITNNYGMQREIFQQKADEYGL
KLEFMFVDAMSMAMIVRPETFGTVAVPNLFGDILTDLGAQLQGGLGMGGSGNINPNGVSM
FEPIHGSAPDIAGQGKANPIAAVLAAQMLLENQGFPQEGKMLHDAVRYVLDHNQTTPDLG
GKLKTAEVGKAIADFILNQKK
NT seq
1146 nt
NT seq
+upstream
nt +downstream
nt
atgaagcatttcgcaattattcccggagacggaatcggaaaggaggtcatcgcggccggt
atggacgtactggacgcagtgtcccagatatcatctttcgaatacgacggagagaacttc
gacatcggttccgacaggtacctcaggaccggcgagctcctcaccgatcaggacgtctcc
gacctcaagaagaaggacgccatttacttcggagcaatcggtgacccccgtgtcaaaccc
ggaatcctcgagggaggaatcctcctcaagatgagggcggtcttcgaccagtacatcaac
ctgaggcctgtgacctcctggttccccctggtccctctgaagagggaggtgaacttcgac
atccacttcctcagggagaatactgaggatttctatatgggtctcggaaagaggttcgga
ccctcctactcagacaagaagaacgccgatggttcctacgacgtcgagctcggagtcaag
agggaatcctacaacatggatttcaaggtcaacgcacaccccaccgccgatgacgattac
tccattgaaatcggactcgtctccaggaagggcatcacccgctgggccgattatgccatg
aaatatgccctcgccaggggagacgacaaggtcactctggtagacaaggccaacgtcatc
accaacaactacggtatgcagagggagatcttccagcagaaggccgacgaatacggcctc
aaactggagttcatgttcgttgatgccatgtccatggccatgatcgtccgtcccgagacc
ttcggcactgttgcagtacctaacctcttcggagacatcctgaccgacctgggagcacag
ctccagggaggactcggcatgggcggcagcggtaacatcaaccccaacggggtcagcatg
ttcgagcccatccatggttctgcgccagatatcgcgggacaaggcaaggccaatcccatc
gcggctgttctcgcagcacagatgctgctggagaaccagggcttcccccaggagggaaag
atgctgcacgacgcagtcaggtacgtccttgaccacaaccagaccacgcccgacctgggc
ggaaagctgaagaccgcagaggtcggaaaggccatcgcggacttcatcctcaaccagaag
aagtga
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