Mesocricetus auratus (golden hamster): 121136483 Help Entry 121136483         CDS       T08306                                  Symbol Insr Name (RefSeq) insulin receptor   KO K04527   insulin receptor [EC:2.7.10.1] Organism maua  Mesocricetus auratus (golden hamster) Pathway maua04010   MAPK signaling pathway maua04014   Ras signaling pathway maua04015   Rap1 signaling pathway maua04022   cGMP-PKG signaling pathway maua04066   HIF-1 signaling pathway maua04068   FoxO signaling pathway maua04072   Phospholipase D signaling pathway maua04150   mTOR signaling pathway maua04151   PI3K-Akt signaling pathway maua04152   AMPK signaling pathway maua04211   Longevity regulating pathway maua04213   Longevity regulating pathway - multiple species maua04520   Adherens junction maua04910   Insulin signaling pathway maua04913   Ovarian steroidogenesis maua04923   Regulation of lipolysis in adipocytes maua04930   Type II diabetes mellitus maua04931   Insulin resistance maua04932   Non-alcoholic fatty liver disease maua04960   Aldosterone-regulated sodium reabsorption maua05010   Alzheimer disease maua05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:maua00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     121136483 (Insr)    04014 Ras signaling pathway     121136483 (Insr)    04015 Rap1 signaling pathway     121136483 (Insr)    04066 HIF-1 signaling pathway     121136483 (Insr)    04068 FoxO signaling pathway     121136483 (Insr)    04072 Phospholipase D signaling pathway     121136483 (Insr)    04022 cGMP-PKG signaling pathway     121136483 (Insr)    04151 PI3K-Akt signaling pathway     121136483 (Insr)    04152 AMPK signaling pathway     121136483 (Insr)    04150 mTOR signaling pathway     121136483 (Insr)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     121136483 (Insr)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     121136483 (Insr)    04923 Regulation of lipolysis in adipocytes     121136483 (Insr)    04913 Ovarian steroidogenesis     121136483 (Insr)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     121136483 (Insr)   09149 Aging    04211 Longevity regulating pathway     121136483 (Insr)    04213 Longevity regulating pathway - multiple species     121136483 (Insr)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     121136483 (Insr)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     121136483 (Insr)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     121136483 (Insr)    04932 Non-alcoholic fatty liver disease     121136483 (Insr)    04931 Insulin resistance     121136483 (Insr)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:maua01001]     121136483 (Insr)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:maua04090]     121136483 (Insr) Enzymes [BR:maua01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      121136483 (Insr) Protein kinases [BR:maua01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    121136483 (Insr) CD molecules [BR:maua04090]  Proteins   121136483 (Insr) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 Motif Other DBs NCBI-GeneID:  121136483 NCBI-ProteinID:  XP_040592898 EnsemblRapid:  ENSMAUG00000028542 LinkDB All DBs Position Unknown AA seq 1368 aa AA seqDB search LFSSPRLTYFAFVVCPLVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDL SFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYGLVIFEMVHLKELGLYNL MNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDVCPGTAKGKTNC PATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHKECLGNCSEPDDPTKCVACR NFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHYKCRNSRKPGCHQYVIHNNKCIPECP SGYTMNSSNLMCIPCLGPCPKVCQILDGEKTIDSVTSAQELRGCTVINGSLIINIRGGNN LAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETLEIGNYSFYALDNQNLR QLWDWNKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCE NELLKFSFIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSW TVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIY VQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWERQAEDSELFELDYC LKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASECCSCPKTDSQILKELEESSFRKTFED YLHNVVFVPRKPSSGNGAEDTRPSRKRRSLEEVGNVTATMPTLADFPNVSSTVVPTSQEE HRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPDERCSVAAYVSARTMPEAKADDIV GPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLR GLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGS IYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPREKITLLRELGQGSF GMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVS KGQPTLVVMELMAHGDLKSHLRSLRPDAENNPGRPPPTLQEMIQMTAEIADGMAYLNAKK FVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFT ASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDPPDNCPERLTDLMRMCWH FNPKMRPTFLEIVNLLKDDLHPSFPEVSFFYSEENKAPESEELEMEFEDMENVPLDGSSH CYREDAGGREGGSSLSIKRTYDEHIPYTHMNGGKKNGRVLTLPRSNPS NT seq 4107 nt NT seq  +upstreamnt  +downstreamnt ctgttctcgagtcccaggctcacctactttgcttttgttgtctgccctctagtgtgccct ggcatggacatccggaacaacctgaccaggctgcatgagctggagaactgctcggttatt gagggccacctgcagatcctcctgatgttcaaaaccaggcctgaagacttccgagacctc agtttccccaaactcatcatgatcacagactacttgcttcttttccgtgtctatggcctg gagagtctgaaagacctcttccccaaccttacagttatccgaggctcccgcctcttcttc aactatggcctggtcatctttgagatggtccacctgaaggagctggggctgtacaatctc atgaacatcacccggggctctgtccgcattgagaagaataatgagctctgctacctggcc accattgactggtcccggatcctggattctgtggaggacaactacattgtgctgaacaaa gatgacaatgaggaatgtggggatgtctgtccaggcaccgccaagggcaagactaattgc cctgccacagtcatcaatgggcagtttgtggaacgttgctggacacacagtcattgtcag aaagtttgccccaccatctgtaagtcacatggctgcacagctgaaggcctgtgctgccac aaggagtgcctaggcaactgttcggaacccgatgaccccaccaagtgtgtggcctgccgc aacttctacctggatggtcggtgtgtggagacctgcccacccccttactaccacttccag gactggcgctgtgtgaacttcagcttctgtcaagaccttcactacaaatgcaggaactct aggaagcctggctgccaccaatacgtcattcacaacaacaagtgcatccctgagtgtcct tctggctataccatgaattccagcaacttgatgtgcatcccatgtctgggaccctgtcct aaggtctgccagatcctggatggcgagaagaccattgactctgtgacatctgcccaggag ctccgaggctgcacagtgatcaatggcagcctcatcatcaacatccgagggggcaacaac ctggcagctgagctcgaggctaaccttggcctcattgaagaaatttcagggttcttaaag atccgacgttcctatgctctagtatctctttctttcttccggaagcttcatctgattcga ggagagaccttggaaatcgggaactactctttctatgccttggacaaccagaacctccga cagctctgggactggaacaaacacaaccttaccatcactcagggcaagctcttcttccac tacaaccccaagctctgcttgtcagaaattcacaagatggaagaagtttctggaactaag ggccgccaggagaggaatgacattgccctgaagaccaatggggaccaggcatcctgtgaa aatgagttacttaaattttccttcattcggacgtcttttgacaagatcttgctgaggtgg gagccctattggccccctgacttccgagacctcctgggattcatgctcttctataaagag gccccttatcagaatgtgacggagtttgatgggcaggatgcttgtggctccaacagctgg actgtggtagatattgacccaccccaaaggtccaacgaccccaagtctcagaccccaagc caccctgggtggctaatgcggggtctcaagccctggactcaatatgctatctttgtcaag accttggttaccttctctgatgaacgccggacctacggagccaaaagtgacatcatctat gtgcagacagatgccactaacccttctgtgcccctggaccccatatcagtttctaattcc tcatctcagattatcttaaagtggaagcccccctccgaccccaatggtaacatcacacac tacctggtctactgggagaggcaggcggaggacagcgagctgtttgagttggattattgt ctcaaagggctgaagctcccctcacggacctggtccccaccctttgaatcggatgattct cagaagcacaatcagagcgagtatgacgactcagccagtgaatgctgctcatgccccaag actgactctcagatcctcaaggagctggaggagtcctcattcaggaagaccttcgaggat taccttcataacgtggtgtttgtccccagaaaaccctcttcaggcaatggtgccgaggac actaggccatcccgaaaacgaagatcccttgaagaggtggggaatgtgacggccaccatg cccacacttgcagattttcccaacgtctcctccaccgttgttcccacgagtcaggaagag cacaggccatttgagaaagtggtgaacaaggagtcacttgtcatctctggcctgagacac ttcactggctaccgcattgagctgcaagcctgcaaccaagactcacccgatgagaggtgc agtgtggctgcctatgtcagtgcccgaaccatgcctgaagctaaggcagatgacatcgtt ggccctgtgacccatgaaatctttgagaacaatgttgtacacttaatgtggcaagagcca aaggagcccaatggtctgatcgtgctgtatgaagtgagctaccggcgctatggtgatgag gagctgcacctctgtgtctcccggaagcattttgccctggagcggggctgcaggcttcga gggctctccccaggaaactacagtgttcgagtccgggctacctccctggcaggcaatggc tcctggacagaacccacctatttttatgtgaccgattatttagatgtcccatcaaatatt gccaaaattatcatcgggccgctcatctttgtcttcctcttcagtgttgtgattggaagt atttatctcttcctgagaaagaggcagccagatggaccaatgggaccgttgtatgcatct tcaaaccctgagtacctcagtgccagtgatgtgtttccttcttctgtgtacgtgccggat gagtgggaggtgcctcgagagaagatcaccctcctacgagagctggggcagggatccttt ggtatggtgtatgagggcaatgccaaggatatcatcaagggcgaggcagagacccgagtt gcggtgaagactgtcaatgagtcagccagtctccgagaacggatcgagttcctcaacgag gcatcagtcatgaagggattcacctgccatcatgtggtccgcctccttggggtggtgtcc aagggccaaccaacactggtagtgatggaattgatggctcatggagacttgaagagtcac ctccgttctctgcgaccggatgctgagaataacccaggccgtcctccccctaccttgcaa gaaatgattcagatgacagcagaaattgctgatggcatggcatacttgaatgccaagaag tttgtgcatcgggacctggcagctcgaaactgcatggttgctcacgattttaccgtcaaa attggagactttggaatgacaagggatatctacgagacagattactatcggaaagggggc aagggcctgctgcccgtgcggtggatgtcacctgagtccctgaaggatggagtgtttacc gcttcttctgatatgtggtcctttggcgtggtcctttgggaaatcaccagcctggctgag caaccttaccaaggcctgtctaatgaacaggtgttgaaatttgtcatggatggaggctat ctggatccacctgataattgtcctgagagactcacggacctgatgcgcatgtgctggcac ttcaaccccaagatgaggccaaccttcctggaaattgtcaacttgctcaaggatgacctc cacccgagctttccagaagtttccttcttctacagcgaagagaacaaggctcctgagagc gaggagctagagatggagttcgaggacatggagaatgtccccttggatgggtcctctcac tgttacagggaagacgctgggggccgggaaggagggtcctctctgagcattaaacggacc tatgacgagcacatcccgtacacccacatgaatgggggcaagaagaatgggcgcgtcctc accttgcccaggtccaacccttcctaa

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