Mycolicibacterium aubagnense: MAUB_23940
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Entry
MAUB_23940 CDS
T07121
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
maub
Mycolicibacterium aubagnense
Pathway
maub00860
Porphyrin metabolism
maub01100
Metabolic pathways
maub01110
Biosynthesis of secondary metabolites
maub01120
Microbial metabolism in diverse environments
maub01240
Biosynthesis of cofactors
Module
maub_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
maub_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
maub00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MAUB_23940 (hemD)
Enzymes [BR:
maub01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MAUB_23940 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MAUB_23940 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BBX84521
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Position
complement(2404098..2405780)
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AA seq
560 aa
AA seq
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MTTRVRKHKPGRITFVGSGPGDPGLLTTRARNVLAHAALVFTDPDVPEAVLALIGTDLPP
TSGPHPADAEPAADAKTDDAAAPAAPAAPAMTFPHGVDVRPALGDPTEVAKLLIAEAKTG
VDVVRLVAGDPLSVDAVITEVNTLAKTAAHFEIVPGLPSSTAVPTYAGLPVGSAHTVADV
RGDVDWAALAAAPGPLILHATVSHLPDAARTLIEYGLTDSTPCVVTAHGTTCQQRSIETT
LAGLLDKAVLEKPVGPEPVGPLAGPLVVTIGKTVAHRAKLNWWESRALYGWTVLVPRTKD
QAGEMSDRLVGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVW
EKFNEFGLDARAFSGVKIACVGQATADKVRAFGINPELVPAGEQSSLGLLDEFPDYDEIF
DPVNRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAHTREMIKTGGFDAVC
FTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPETAAVGPLVEALAEH
AARLRAEGALPPPRKKSRRR
NT seq
1683 nt
NT seq
+upstream
nt +downstream
nt
atgacgacccgagtgcgtaagcacaagcccggccgcatcacctttgtcggttccggcccc
ggtgacccgggcctgttgacgacgcgtgcgcggaacgttttggcgcatgcggcattggtt
ttcaccgatcctgatgtgcccgaggcggtgctggcgctgatcggtaccgatctgccgccg
acctccgggccgcacccggccgacgccgagccggccgccgatgccaaaaccgacgacgct
gccgctccggccgcgccggcggccccggccatgacgttcccgcatggtgtcgacgtccgc
cccgccctgggtgacccgaccgaggtggccaagctgctcatcgccgaggccaagaccggc
gtcgacgtggtgcgtctggtggcgggcgacccgctgtcggtcgacgccgtcatcaccgag
gtgaacaccttggccaagaccgcggcgcacttcgagattgtgccgggcctgccgtcgtcg
acggcggtgcccacctacgcgggcctgcccgtcggctcggcgcacaccgtggccgacgtc
cgcggtgacgtggactgggccgcgctggccgccgctccggggccgctgatcctgcacgcg
acggtgtcgcacctgccggatgccgcgcgcaccctgatcgaatacggcctcaccgacagc
accccgtgcgtcgtgaccgcccacggcaccacgtgccagcagcggtccatcgagaccacg
ctggccgggctgctggacaaggccgtgctggagaagccggtcggccccgagcccgtcggc
ccgctggcgggtccgctggtcgtcaccatcggcaagacggtggcgcaccgggccaagctg
aactggtgggagagccgcgcgctgtacggctggaccgtgctggtgccgcgcaccaaggac
caggccggcgagatgagcgatcggctggtgggccacggcgccctgcccatcgaggtgccg
accatcgccgtcgagccgccgcgcagccccgcccagatggagcgtgcggtcaagggcctg
gtcgacggtcgtttccagtgggtcgtgttcacctccaccaacgccgtgcgcgcggtgtgg
gagaagttcaacgaattcggtctggatgcccgcgcgttctccggtgtgaagatcgcgtgc
gtcggtcaggccaccgccgacaaggtgcgtgcgttcggcatcaatcccgagctggtgccg
gccggtgagcagtcgtcgttgggcctgctcgacgaattcccggactacgacgaaattttc
gacccggtgaaccgggtgctgctgccgcgcgccgacatcgccaccgagacgctggccgag
ggcctgcgcgagcgtggctgggagatcgaggacgtcacggcctaccggaccgtccgtgcg
gcaccgccgccggcgcatacccgcgagatgatcaagaccggtggtttcgacgccgtctgc
ttcacctcgagctccacggtgcgcaacttggtcggcatcgccggcaagccgcacgcccgg
accatcgtcgcctgcatcggcccgaaaaccgctgaaaccgcagccgaattcggcctgcgt
gtggacgtgcagccggagaccgccgccgtgggtccgctggtcgaggcgctggccgagcac
gccgctcgcctgcgcgccgagggtgccctgccacccccgcgtaagaagagccggcgtcgc
tag
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