Mycolicibacterium aurum: NCTC10437_00707
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Entry
NCTC10437_00707 CDS
T06794
Symbol
cysG_1
Name
(GenBank) uroporphyrinogen III synthase HEM4
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mauu
Mycolicibacterium aurum
Pathway
mauu00860
Porphyrin metabolism
mauu01100
Metabolic pathways
mauu01110
Biosynthesis of secondary metabolites
mauu01120
Microbial metabolism in diverse environments
mauu01240
Biosynthesis of cofactors
Module
mauu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mauu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mauu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
NCTC10437_00707 (cysG_1)
Enzymes [BR:
mauu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
NCTC10437_00707 (cysG_1)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
NCTC10437_00707 (cysG_1)
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
VEG51595
UniProt:
A0A448IGK1
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Position
1:725914..727611
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AA seq
565 aa
AA seq
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MSLRGRKNKPGHITFVGSGPGDPGLLTTRARSVLANAALVFTDPDVPEAILALVGCELPP
PSGPLPPVAAAVAPKPGADDAAAQPDADAGETSVDAVIPGGPDVRPALGDPAEVAKTLAN
EARTGVDVVRLVAGDPLSVDSVITEVNALARTQLNFEIVPGLPDTSAVPTYAGLPLGSAH
TVADVRGDVDWAALAAAPGPLILHATASHLPEAARTLIEYGLADSTPAVVTANGTTCQQR
SVETTLGGLLDKAVLDRPAGIDAAGPLTGTLVVTIGRTVANRAKLNWWESRALYGWTVLV
PRTKDQAGEMSDRLVGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNA
VRAVWEKFNEFGLDARAFSGVKIACVGQATAERVREFGINPELVPTGEQSSLGLLDEFPP
YDDIFDPVNRVLLPRADIATETLAEGLRELGWEIEDVTAYRTVRAAPPPAHTREMIKTGG
FDAVCFTSSSTVRNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPEVAAVGPLVE
ALAEHAARLRAEGALPPPRKKSRRR
NT seq
1698 nt
NT seq
+upstream
nt +downstream
nt
atgagcttgcgaggacgcaagaacaagcccggccacatcacgttcgtcggctcagggccc
ggggatccggggctgctgacaacgcgtgcccgcagcgtgttggccaacgccgccctggtc
ttcaccgaccccgacgtgccggaggcgatcctggccctggtgggctgcgagttgccgcct
ccctccggtccgttgccccctgtcgccgccgcggtggcccccaagcccggcgccgacgat
gccgcggcccagccggatgccgatgcgggcgagacgtcggtcgacgccgtcatccccggt
ggtccggacgtgcggcccgcgctgggtgatccggccgaggtcgccaagacactggcgaac
gaggctcgtaccggagtcgacgtggtgcgtctggtcgcgggcgacccgctgtcggtcgac
tcggtgatcaccgaggtcaacgcgctggcccgaacgcagctgaacttcgagatcgtcccc
ggcctgcccgacacctccgcggtgcccacctacgcgggattgccgctcgggtcggcgcac
accgtcgccgacgtgcgcggcgacgtcgactgggcggccctggcggctgcgccgggtccg
ctgatcctgcacgcgacggcgtcgcacctaccggaggcggcgcgcacgctgatcgagtac
ggcctcgccgacagcacgcctgccgtggtcaccgccaacgggaccacgtgccagcagcgc
tcggtggagaccaccctcggcggactgctcgacaaggcagtgctggaccggcctgccggc
atcgacgccgcaggcccgctgacggggacgctggtcgtcacgatcggccgtaccgtcgcc
aaccgcgccaagctgaactggtgggagagccgcgccctgtacgggtggaccgtgctggtg
ccgcgcaccaaggaccaggccggcgagatgagtgatcgcctggtcggacacggggccctg
cccatcgaggtgccgaccatcgcagtcgagccgccccgtagcccggcccaaatggaaagg
gccgtcaagggtttggtggacggcaggttccagtgggtggtgttcacctccaccaacgcc
gtgcgtgccgtatgggagaagttcaacgagttcgggctcgacgcccgcgcgttctccggc
gtcaagatcgcctgtgtcggtcaggccacggccgaacgcgtgcgcgaattcgggatcaat
ccggagctggtgcccacgggtgagcagagctcgctcggcctgctcgacgaattcccgccg
tatgacgacattttcgatccggtgaaccgggtgctgctgccgcgtgccgacatcgccacc
gagacactggccgaaggtctgcgcgaactcggttgggagatcgaggatgtcacggcctat
cgcacggttcgggccgctccgccgccggcgcacacccgcgagatgatcaagaccggcggg
ttcgacgccgtgtgcttcacgtccagctcgaccgtgcgcaacctcgtcggcatcgcgggt
aagccgcacgcccgcaccatcgttgcctgcatcgggcccaagacggcggagaccgcagcc
gagttcggtttgcgtgtcgacgtccagcccgaggtggccgcggtcggacctctggtcgag
gcgctggccgagcacgccgcccggttgcgggccgagggcgcgctgccgcccccgcggaag
aaaagccgccgccgctag
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