Mycobacterium avium subsp. paratuberculosis E1: RC58_20475
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Entry
RC58_20475 CDS
T03787
Name
(GenBank) uroporphyrin-III methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mavi
Mycobacterium avium subsp. paratuberculosis E1
Pathway
mavi00860
Porphyrin metabolism
mavi01100
Metabolic pathways
mavi01110
Biosynthesis of secondary metabolites
mavi01120
Microbial metabolism in diverse environments
mavi01240
Biosynthesis of cofactors
Module
mavi_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mavi_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mavi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
RC58_20475
Enzymes [BR:
mavi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
RC58_20475
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
RC58_20475
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Gene cluster
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AJK77107
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Position
4418201..4419859
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AA seq
552 aa
AA seq
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MTTRGRKPTPGRITYVGSGPGDPGLLTARAATVLANAALVFTDPDVPEPVLALIGKDLPP
VSGPAPAEPASNGEGSGSEQGQAQPAVISGGPDIRPALGDPAEVAKTLTAEARTGVDVVR
LVAGDPLTVDAVITEVNAIARSHLHIEIVPGLAPTNAVPTYAGLPLGSSHTMADVRGDVD
WEALAAAPGPLILQATASHLADAARTLIEHELAENTPCVVTAHGTTCQQRSIETTLQGLT
DSAVLGGTDPAGPLTGPLVVTIGKTVSARTKLNWWESRALYGWTVLVPRTKDQAGEMSER
LTSYGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFGEFGL
DARAFSGVKIACVGESTADRVRAFGISPELVPAGEQSSLGLLDDFPPYDSVFDPVNRVLL
PRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAETREMIKTGGFDAVCFTSSSTVR
NLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPETAAVGPLVDTLAEHAARLRAEG
ALPPPRKKSRRR
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
atgacgacgcgagggcgtaagccgacacccggccgcatcacgtacgtgggctccggcccg
ggtgacccgggactgttgacggcccgggccgcgacggtgctggcgaacgccgcgctggtg
ttcaccgaccccgacgtgcccgagccggtgctggcgctgatcggcaaggacctgccaccg
gtgtccggcccggcgccggccgagccggcgtccaacggcgagggctccggctccgagcag
gggcaggcgcagccggcggtgatctccggtggcccggacatccgcccggcgctgggtgat
cccgccgaggtggccaagacgctgaccgccgaggcgcgcaccggtgtcgacgtggtgcgg
ctggtggccggtgacccgctgaccgtcgacgccgtcatcaccgaggtcaacgccatcgcc
cgcagccacctgcacatcgagatcgtgcccgggctggcgcccaccaacgccgtcccgacc
tacgcgggcctgccgctgggctcctcgcacaccatggccgacgtgcgcggtgacgtggac
tgggaggcgctggccgccgcgcccggcccgctgatcctgcaggccaccgcgtcgcacctg
gccgacgcggcgcgcaccctgatcgaacacgaactggccgagaacaccccgtgcgtggtc
accgcgcacggcaccacctgccagcagcgctccatcgagaccacgctgcaggggctgacc
gactcggcggtgctgggcggcaccgaccccgccggcccgctgaccggtccgctggtggtg
accatcggcaagacggtgagcgcccggaccaagctgaactggtgggagagccgcgccctg
tacggctggaccgtgctggtgccccgcaccaaggaccaggccggcgagatgagcgagcgg
ctgacgtcgtacggcgcgctgccgatcgaggtgccgaccatcgccgtcgagccgccgcgc
agccccgcgcagatggagcgtgccgtcaagggattggtcgacggccgcttccagtgggtg
gtgttcacctccaccaacgcggtgcgcgcggtgtgggagaagttcggcgagttcggtctg
gacgcgcgcgcgttctccggggtgaagatcgcctgtgtgggcgagtcgacggccgaccgg
gtgcgggcgttcgggatcagccccgagctggtgccggccggcgagcagtcctcgctgggt
ctgctcgacgacttcccgccctacgacagcgttttcgacccggtgaaccgggtgctgttg
ccgcgggccgacatcgccaccgagacgctggccgaggggctgcgcgaacggggttgggag
atcgaggatgtcacggcctaccggacggtgcgggccgcgccgccgccggcggagacccgg
gagatgatcaagaccggcggcttcgacgcggtgtgcttcacgtccagctccacggtgcgc
aacctggtcggcatcgccggcaagccgcacgcccggacgatcatcgcctgcatcggtccc
aagaccgccgagaccgccgccgagttcggcctgcgggtggatgtccagcccgagaccgcg
gcggtgggcccgctggtcgacactctggccgaacacgccgcgcggttgcgcgccgagggg
gcgctgccaccgccgcgcaagaagagccgcaggcgctag
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