Mycobacterium avium subsp. paratuberculosis E93: RE97_20525
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Entry
RE97_20525 CDS
T03847
Name
(GenBank) uroporphyrin-III methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mavu
Mycobacterium avium subsp. paratuberculosis E93
Pathway
mavu00860
Porphyrin metabolism
mavu01100
Metabolic pathways
mavu01110
Biosynthesis of secondary metabolites
mavu01120
Microbial metabolism in diverse environments
mavu01240
Biosynthesis of cofactors
Module
mavu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:
mavu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
RE97_20525
Enzymes [BR:
mavu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
RE97_20525
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
RE97_20525
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AJK81331
UniProt:
A0A7L5MQ70
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Position
4422980..4424638
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AA seq
552 aa
AA seq
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MTTRGRKPTPGRITYVGSGPGDPGLLTARAATVLANAALVFTDPDVPEPVLALIGKDLPP
VSGPAPAEPASNGEGSGSEQGQAQPAVISGGPDIRPALGDPAEVAKTLTAEARTGVDVVR
LVAGDPLTVDAVITEVNAIARSHLHIEIVPGLAPTNAVPTYAGLPLGSSHTMADVRGDVD
WEALAAAPGPLILQATASHLADAARTLIEHELAENTPCVVTAHGTTCQQRSIETTLQGLT
DSAVLGGTDPAGPLTGPLVVTIGKTVSARTKLNWWESRALYGWTVLVPRTKDQAGEMSER
LTSYGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFGEFGL
DARAFSGVKIACVGESTADRVRAFGISPELVPAGEQSSLGLLDDFPPYDSVFDPVNRVLL
PRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAETREMIKTGGFDAVCFTSSSTVR
NLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAARLRAEG
ALPPPRKKSRRR
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
atgacgacgcgagggcgtaagccgacacccggccgcatcacgtacgtgggctccggcccg
ggtgacccgggactgttgacggcccgggccgcgacggtgctggcgaacgccgcgctggtg
ttcaccgaccccgacgtgcccgagccggtgctggcgctgatcggcaaggacctgccaccg
gtgtccggcccggcgccggccgagccggcgtccaacggcgagggctccggctccgagcag
gggcaggcgcagccggcggtgatctccggtggcccggacatccgcccggcgctgggtgat
cccgccgaggtggccaagacgctgaccgccgaggcgcgcaccggtgtcgacgtggtgcgg
ctggtggccggtgacccgctgaccgtcgacgccgtcatcaccgaggtcaacgccatcgcc
cgcagccacctgcacatcgagatcgtgcccgggctggcgcccaccaacgccgtcccgacc
tacgcgggcctgccgctgggctcctcgcacaccatggccgacgtgcgcggtgacgtggac
tgggaggcgctggccgccgcgcccggcccgctgatcctgcaggccaccgcgtcgcacctg
gccgacgcggcgcgcaccctgatcgaacacgaactggccgagaacaccccgtgcgtggtc
accgcgcacggcaccacctgccagcagcgctccatcgagaccacgctgcaggggctgacc
gactcggcggtgctgggcggcaccgaccccgccggcccgctgaccggtccgctggtggtg
accatcggcaagacggtgagcgcccggaccaagctgaactggtgggagagccgcgccctg
tacggctggaccgtgctggtgccccgcaccaaggaccaggccggcgagatgagcgagcgg
ctgacgtcgtacggcgcgctgccgatcgaggtgccgaccatcgccgtcgagccgccgcgc
agccccgcgcagatggagcgtgccgtcaagggattggtcgacggccgcttccagtgggtg
gtgttcacctccaccaacgcggtgcgcgcggtgtgggagaagttcggcgagttcggtctg
gacgcgcgcgcgttctccggggtgaagatcgcctgtgtgggcgagtcgacggccgaccgg
gtgcgggcgttcgggatcagccccgagctggtgccggccggcgagcagtcctcgctgggt
ctgctcgacgacttcccgccctacgacagcgttttcgacccggtgaaccgggtgctgttg
ccgcgggccgacatcgccaccgagacgctggccgaggggctgcgcgaacggggttgggag
atcgaggatgtcacggcctaccggacggtgcgggccgcgccgccgccggcggagacccgg
gagatgatcaagaccggcggcttcgacgcggtgtgcttcacgtccagctccacggtgcgc
aacctggtcggcatcgccggcaagccgcacgcccggacgatcatcgcctgcatcggtccc
aagaccgccgagaccgccgccgagttcggcctgcgggtggatgtccagcccgagaccgcg
gcggtgggcccgctggtcgacgctctggccgaacacgccgcgcggttgcgcgccgagggg
gcgctgccaccgccgcgcaagaagagccgcaggcgctag
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