KEGG   PATHWAY: mbo01053
Entry
mbo01053                    Pathway                                
Name
Biosynthesis of siderophore group nonribosomal peptides - Mycobacterium tuberculosis variant bovis AF2122/97
Class
Metabolism; Metabolism of terpenoids and polyketides
Pathway map
mbo01053  Biosynthesis of siderophore group nonribosomal peptides
mbo01053

Organism
Mycobacterium tuberculosis variant bovis AF2122/97 [GN:mbo]
Gene
BQ2027_MB3241  entC; PROBABLE ISOCHORISMATE SYNTHASE ENTC (ISOCHORISMATE HYDROXYMUTASE) (ENTEROCHELIN BIOSYNTHESIS) [KO:K02361] [EC:5.4.4.2]
BQ2027_MB2407C  mbtI; isochorismate synthase mbti [KO:K04781] [EC:5.4.4.2 4.2.99.21]
BQ2027_MB2405  mbtA; BIFUNCTIONAL ENZYME MBTA: SALICYL-AMP LIGASE (SAL-AMP LIGASE) + SALICYL-S-ArCP SYNTHETASE [KO:K04787] [EC:6.3.2.-]
BQ2027_MB2404C  mbtB; PHENYLOXAZOLINE SYNTHASE MBTB (PHENYLOXAZOLINE SYNTHETASE) [KO:K04788]
BQ2027_MB2401C  mbtE; PEPTIDE SYNTHETASE MBTE (PEPTIDE SYNTHASE) [KO:K04789]
BQ2027_MB2403C  mbtC; POLYKETIDE SYNTHETASE MBTC (POLYKETIDE SYNTHASE) [KO:K04790]
BQ2027_MB2402C  mbtD; POLYKETIDE SYNTHETASE MBTD (POLYKETIDE SYNTHASE) [KO:K04791]
BQ2027_MB2400C  mbtF; PEPTIDE SYNTHETASE MBTF (PEPTIDE SYNTHASE) [KO:K04792]
BQ2027_MB2399C  mbtG; LYSINE-N-OXYGENASE MBTG (L-LYSINE 6-MONOOXYGENASE) (LYSINE N6-HYDROXYLASE) [KO:K04793]
Compound
C00158  Citrate
C00196  2,3-Dihydroxybenzoate
C00230  3,4-Dihydroxybenzoate
C00251  Chorismate
C00315  Spermidine
C00805  Salicylate
C00885  Isochorismate
C02637  3-Dehydroshikimate
C04171  (2S,3S)-2,3-Dihydro-2,3-dihydroxybenzoate
C05821  Enterochelin
C06769  Vibriobactin
C12037  Pyochelin
C12038  Yersiniabactin
C12216  Mycobactin S
C12219  Corynebactin
C12220  Myxochelin A
C12221  Myxochelin B
C20883  3,4-Dihydroxybenzoyl-[aryl-carrier protein]
C20884  (3,4-Dihydroxybenzoyl)adenylate
C20885  N-Citryl-spermidine
C20952  N1-(3,4-Dihydroxybenzoyl)-N8-citryl spermidine
C22004  N8,N'8-Citryl-bis(spermidine)
C22069  N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine)
C22273  Petrobactin
Reference
PMID:12040125
  Authors
Crosa JH, Walsh CT.
  Title
Genetics and assembly line enzymology of siderophore biosynthesis in bacteria.
  Journal
Microbiol Mol Biol Rev 66:223-49 (2002)
DOI:10.1128/MMBR.66.2.223-249.2002
Reference
PMID:9818149
  Authors
Gehring AM, DeMoll E, Fetherston JD, Mori I, Mayhew GF, Blattner FR, Walsh CT, Perry RD.
  Title
Iron acquisition in plague: modular logic in enzymatic biogenesis of yersiniabactin by Yersinia pestis.
  Journal
Chem Biol 5:573-86 (1998)
DOI:10.1016/S1074-5521(98)90115-6
Reference
PMID:11029592
  Authors
Silakowski B, Kunze B, Nordsiek G, Blocker H, Hofle G, Muller R.
  Title
The myxochelin iron transport regulon of the myxobacterium Stigmatella aurantiaca Sg a15.
  Journal
Eur J Biochem 267:6476-85 (2000)
DOI:10.1046/j.1432-1327.2000.01740.x
Reference
PMID:11112537
  Authors
Keating TA, Marshall CG, Walsh CT.
  Title
Vibriobactin biosynthesis in Vibrio cholerae: VibH is an amide synthase homologous to nonribosomal peptide synthetase condensation domains.
  Journal
Biochemistry 39:15513-21 (2000)
DOI:10.1021/bi001651a
Reference
PMID:10692387
  Authors
Hantash FM, Earhart CF.
  Title
Membrane association of the Escherichia coli enterobactin synthase proteins EntB/G, EntE, and EntF.
  Journal
J Bacteriol 182:1768-73 (2000)
DOI:10.1128/JB.182.6.1768-1773.2000
Related
pathway
mbo00400  Phenylalanine, tyrosine and tryptophan biosynthesis
KO pathway
ko01053   
LinkDB

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