Mycolicibacterium brumae: L2Z93_003373
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Entry
L2Z93_003373 CDS
T08531
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mbrm
Mycolicibacterium brumae
Pathway
mbrm00860
Porphyrin metabolism
mbrm01100
Metabolic pathways
mbrm01110
Biosynthesis of secondary metabolites
mbrm01120
Microbial metabolism in diverse environments
mbrm01240
Biosynthesis of cofactors
Module
mbrm_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mbrm_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mbrm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
L2Z93_003373
Enzymes [BR:
mbrm01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
L2Z93_003373
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
L2Z93_003373
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
UWW10246
LinkDB
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Position
complement(3450133..3451767)
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AA seq
544 aa
AA seq
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MTTRGRKAKPGRITFVGSGPGDPGLLTTRAKSVLGAAALVFTDPDVPEAVLRLAGADLPP
TVGPDPVAAPAGEEAAAPIVSGGAEVRPALGDPAEVAKTMVAEARKGNDVVRLVFGDPLS
LDPVLAEVNAIARTQLVFDIVPGLPATTAVPTYGGLPLGSSHTIADVRGDVDWAALAAAP
GPLILQAGPEHLADAARTLIDYGLADNTPCVVTAQGTTCQQRSVETTLSGLTERAALGAA
DPAGPLTGPLVVTIGRTVANRAKLNWWESRALYGWTVLVPRTKDQAGEMSDKLVGHGALP
IEVPTIAVEPPRSPAQMERAVKGLVDGRYQWVVFTSTNAVRAVWEKFGEFGLDARAFSGV
KIACVGEATAERVRAFGISPELVPSGEQSSLGLLAEFPPYDEIFDPVNRVLLPRADIATE
TLAEGLRESGWEIEDVTAYRTVRAAPPPAQTREMIKTGGFDAVCFTSSSTVRNLVGIAGK
PHARTIVACIGPKTAETAAEFGLRVDVQPETAAIGPLVDALAEHAARLRAEGALPPPRKK
SRRR
NT seq
1635 nt
NT seq
+upstream
nt +downstream
nt
atgaccacgcgagggcgtaaggccaagccggggcgtatcacgtttgtgggctccggcccg
ggggaccccggtctgctgaccacgcgggccaagtcggtgctcggcgccgcggccctggtg
ttcaccgatcccgatgtccccgaggccgtgctgcggctggccggcgccgatctgccgccg
accgtcggacccgacccggtggccgccccggccggcgaagaggccgcggccccgatcgtc
agcggcggcgccgaggtgcgccccgcgctcggcgatcccgccgaggtcgccaagaccatg
gtcgccgaggcccgcaagggcaacgacgtggtgcgcctggtgttcggcgacccgctgtcg
ttggacccggtgctggccgaggtgaacgcgatcgcgcggacccagctggtcttcgacatc
gtgccgggcctgcccgccaccaccgcggtgcccacctacggcggcctgccgctgggctcc
tcgcacactatcgccgacgtccgcggcgacgtggactgggcggcgctggccgccgctccc
ggcccactgatcctgcaggccggccccgagcatctcgcggacgcggcccgcaccctgatc
gactacggcctggccgacaacaccccctgtgtggtcaccgcccagggcaccacctgccag
cagcgcagcgtggagacgacgctgagcggcctgaccgaacgcgccgcgctcggcgccgcc
gacccggccggtccgctgaccggtccgctggtggtcaccatcggccgcaccgtcgccaac
cgcgccaagctgaactggtgggagagccgcgccctgtacggctggaccgtgctggtgccg
cgcaccaaggaccaggccggtgagatgagcgacaagctcgtcggccacggcgcgctgccg
atcgaggtgcccaccatcgccgtcgagccgccgcgcagccccgcgcagatggaacgcgcc
gtcaagggtctggtcgacggccgctaccagtgggtggtgttcacctccaccaacgcggtg
cgcgcggtctgggagaagttcggcgagttcggcctggacgcccgcgcgttctccggggtc
aagatcgcctgcgtcggcgaggccaccgcggagcgggtgcgcgccttcggcatcagcccc
gagctggtgccctccggtgagcagtcctcgctgggcctgctggccgagttcccgccgtac
gacgagatcttcgacccggtcaaccgggtgctgctgccgcgtgccgacatcgccaccgag
accctggccgaaggcctgcgcgaatccggctgggagatcgaggacgtcaccgcctaccgc
accgtgcgcgccgccccgccgccggcgcagacccgcgagatgatcaagaccggcgggttc
gacgcggtctgcttcacctccagctccacggtccgcaacctggtcggcatcgccggcaag
ccgcacgcccggaccatcgtggcgtgcatcggccccaagaccgccgagacggccgccgag
ttcggcctgcgggtggacgtgcagccggagaccgccgcgatcggcccgctggtcgacgcg
cttgccgagcacgccgcccggctgcgcgccgagggcgcgctgcccccgccgcgcaagaag
agccgtcgccggtag
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