Methylococcus capsulatus: MCA2065
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Entry
MCA2065 CDS
T00205
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mca
Methylococcus capsulatus
Pathway
mca00290
Valine, leucine and isoleucine biosynthesis
mca00660
C5-Branched dibasic acid metabolism
mca01100
Metabolic pathways
mca01110
Biosynthesis of secondary metabolites
mca01210
2-Oxocarboxylic acid metabolism
mca01230
Biosynthesis of amino acids
Module
mca_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MCA2065 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MCA2065 (leuC)
Enzymes [BR:
mca01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MCA2065 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MCA2065 (leuC)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
AAU91966
UniProt:
Q606F2
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Position
complement(2221600..2223012)
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AA seq
470 aa
AA seq
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MSGKTLYDKLWDDHVVHVDADGSCLIYIDRHLIHEVTSPQAFEGLRMAGRVPWRVDANLA
VADHNVPTADRDRGIADPVSRLQVETLDKNCADFGITEFAMDDVRQGIVHVIGPEQGATL
PGMTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQCLVQRKAKNMLVRVQGKLAPGVT
AKDLVLAVIGRIGTAGGTGYTIEFAGEAIRGLSMEGRMTVCNMAIEAGARAGLVAVDEVT
LDYLEGRPFAPAGALWERAVEAWKDLHSDPDAVFDKVVEIDAASIKPQVTWGTSPEQVVP
VDAEVPDPATEADPVRRESMERALQYMDLLPGTPIGAIRVDRVFIGSCTNARIEDLRAAA
EVVRGHKRAASVKQALVVPGSGLVKRQAEQEGLDKVFLEAGFEWRDPGCSMCLAMNADRL
EPGERCASTSNRNFEGRQGYGGRTHLVSPAMAAAAAIHGHFVDITEGGRA
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
atgagcggaaaaaccctttacgacaagctgtgggacgaccacgtcgtgcatgtcgatgcg
gacggatcgtgcctgatctacatcgatcgtcatctaatccacgaggtgacctcgcctcag
gcattcgaagggctgcggatggcggggcgtgtaccctggcgggtggatgccaatcttgcg
gtggccgaccacaacgtccccaccgccgaccgcgacaggggtatcgccgatccggtgtcg
cgcctgcaggtggaaaccctggacaagaactgcgccgatttcggcatcaccgaattcgcg
atggacgacgtgcgccagggtatcgtgcatgtgatcgggcccgagcagggcgcgaccctg
ccgggcatgaccatcgtttgcggcgattcgcatacttcgactcacggtgctttcggggcg
ctcgccttcgggatcggcacttccgaggtcgagcacgtactggccacgcaatgcctggtg
cagcgcaaggcgaagaacatgctggtccgcgtccagggcaagctggcgccgggcgtgacg
gcgaaagatctggtactggcggtcatcggccgtatcggaaccgccggcggcaccggctac
accatcgaattcgctggcgaagccattcgcggcctgtcgatggaaggccggatgacggtc
tgcaacatggcgatcgaggcgggcgcacgtgccggcctggtggcggtggacgaagtcacg
ctcgactatctcgagggccgcccgttcgctccggcgggcgcgttgtgggagcgggcggtc
gaggcatggaaagacctgcacagcgatccggatgcggtattcgacaaggtcgtcgagatc
gatgccgccagcatcaagccgcaggtgacctggggaacttcgccggaacaggtcgtgccg
gtggatgccgaggtgcccgacccggccacggaagccgatcccgtgcggcgggaaagcatg
gagcgggcgctgcagtacatggatctcctgccgggcacgccaatcggcgcgatccgggtc
gatcgggtgttcatcggctcctgcaccaatgccaggatcgaggatctgcgcgccgcggcg
gaagtcgtccgggggcacaagcgcgctgccagcgtgaagcaggcactggtggtgcccggc
tcgggtttggtcaagcggcaggcggagcaggaggggctggacaaggtgttcctcgaggcc
ggtttcgaatggcgcgacccgggttgttccatgtgtctggcgatgaacgccgaccgcctg
gaacccggcgagcgttgcgcctcgacctccaaccggaattttgaggggcgccagggctat
ggcgggcgtacccatctggtgagtccggccatggcggctgcggcggccattcacgggcat
ttcgtcgacatcaccgaaggagggcgcgcatga
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